Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Deepa Bedi"'
Publikováno v:
Current Oncology, Vol 31, Iss 3, Pp 1195-1206 (2024)
Precision cancer medicine primarily aims to identify individual patient genomic variations and exploit vulnerabilities in cancer cells to select suitable patients for specific drugs. These genomic features are commonly determined by gene sequencing p
Externí odkaz:
https://doaj.org/article/39507bde73bc4590a3f9b8ff8b61649a
Autor:
Anusha Angajala, Hughley Raymond, Aliyu Muhammad, Md Shakir Uddin Ahmed, Saadia Haleema, Monira Haque, Honghe Wang, Moray Campbell, Rachel Martini, Balasubramanian Karanam, Andrea G. Kahn, Deepa Bedi, Melissa Davis, Ming Tan, Windy Dean-Colomb, Clayton Yates
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract We previously found that QNBC tumors are more frequent in African Americans compared to TNBC tumors. To characterize this subtype further, we sought to determine the miRNA–mRNA profile in QNBC patients based on race. Both miRNA and mRNA ex
Externí odkaz:
https://doaj.org/article/772acc33da934a7eadb043767e7ca6e8
Autor:
Jonathan Marable, Damien Ruiz, Anil K. Jaiswal, Ritankar Bhattacharya, Robert Pantazes, Payal Agarwal, Amol S. Suryawanshi, Deepa Bedi, Amarjit Mishra, Bruce F. Smith, Maninder Sandey
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Cancer is the leading cause of death in the geriatric dog population. Currently, the use of immune checkpoint inhibitors (ICIs) such as anti-CTLA4 antibodies has markedly improved the prognosis of several cancers in their advanced stages. Ho
Externí odkaz:
https://doaj.org/article/a1254a4909ce448fbb10ccd72cd4ca3b
Autor:
Damien Ruiz, Chloe Haynes, Jonathan Marable, Chetan Pundkar, Rebecca L. Nance, Deepa Bedi, Payal Agarwal, Amol S. Suryawanshi, Amarjit Mishra, Bruce F. Smith, Maninder Sandey
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105158- (2022)
Summary: Recent breakthroughs in cancer immunotherapy have provided unprecedented clinical benefits to human cancer patients. Cancer is also one of the most common causes of death in pet dogs. Thus, canine-specific immune therapies targeting similar
Externí odkaz:
https://doaj.org/article/9054f4d3c2764d04bfb6e231f7445b53
Autor:
Md Shakir Uddin Ahmed, Brittany D. Lord, Benjamin Adu Addai, Sandeep K. Singhal, Kevin Gardner, Ahmad Bin Salam, Anghesom Ghebremedhin, Jason White, Iqbal Mahmud, Rachel Martini, Deepa Bedi, Huixian Lin, Jacqueline D. Jones, Balasubramanyanam Karanam, Windy Dean-Colomb, William Grizzle, Honghe Wang, Melissa Davis, Clayton C. Yates
Publikováno v:
Cancers, Vol 15, Iss 8, p 2282 (2023)
African American (AA) women with breast cancer are more likely to have higher inflammation and a stronger overall immune response, which correlate with poorer outcomes. In this report, we applied the nanostring immune panel to identify differences in
Externí odkaz:
https://doaj.org/article/6d7337b62a744d0597bd95df7d61d53d
Publikováno v:
Cancers, Vol 14, Iss 22, p 5599 (2022)
Among the different components of the breast cancer microenvironment are adipocytes, which are mainly composed of differentiated adipocytes and adipose progenitors. The role of obesity in tumor progression has become a key topic in clinical studies,
Externí odkaz:
https://doaj.org/article/e07c839d311949319b7a101956aa2e44
Autor:
Madison D. Hogans, Will P. Kretzschmar, Theresa A. Higgins, Atonu Chakrabortty, Rebecca L. Nance, Bruce F. Smith, Deepa Bedi, Maninder Sandey, Payal Agarwal
Publikováno v:
Advances in Virology, Vol 2022 (2022)
Canine adenovirus type 2 (CAV2) is a nonhuman adenovirus with a known ability to infect human and canine cells. The cell surface receptors involved in CAV2 transduction are still unknown. Identification of these would provide valuable information to
Externí odkaz:
https://doaj.org/article/19ee01877e3b4f32830789c324628e66
Autor:
Anusha Angajala, Essynce Mothershed, Melissa B. Davis, Shweta Tripathi, Qinghua He, Deepa Bedi, Windy Dean-Colomb, Clayton Yates
Publikováno v:
Translational Oncology, Vol 12, Iss 3, Pp 493-501 (2019)
PURPOSE: Despite the availability of current standards of care treatments for triple negative breast cancer (TNBC), many patients still die from this disease. Quadruple negative tumors, which are TNBC tumors that lack androgen receptor (AR), represen
Externí odkaz:
https://doaj.org/article/91e3dfc1e2764525b0405d1a184aa5fc
Autor:
Kelvin M. Jones, Balasubramanyam Karanam, Jacqueline Jones-Triche, Maninder Sandey, Henry J. Henderson, Rajeev S. Samant, Samuel Temesgen, Clayton Yates, Deepa Bedi
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Epithelial to mesenchymal transition (EMT) is believed to be crucial for primary tumors to escape their original residence and invade and metastasize. To properly define EMT, there is a need for ligands that can identify this phenomenon in tumor tiss
Externí odkaz:
https://doaj.org/article/def002a3fad54bdbb4569b2fc2213ded
Autor:
Henry J Henderson, Balasubramanyam Karanam, Rajeev Samant, Komal Vig, Shree R Singh, Clayton Yates, Deepa Bedi
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189662 (2017)
The molecular mechanisms involved in breast cancer progression and metastasis still remain unclear to date. It is a heterogeneous disease featuring several different phenotypes with consistently different biological characteristics. Neuroligins are n
Externí odkaz:
https://doaj.org/article/8700c840e9eb45a0bf5a4dfc041fde30