Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Deendyal Bhurta"'
Autor:
Kathleen Shah, Muralidhara Rao Maradana, M. Joaquina Delàs, Amina Metidji, Frederike Graelmann, Miriam Llorian, Probir Chakravarty, Ying Li, Mauro Tolaini, Michael Shapiro, Gavin Kelly, Chris Cheshire, Deendyal Bhurta, Sandip B. Bharate, Brigitta Stockinger
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Rapid intestinal regeneration after injury is critical to maintain barrier integrity and homeostasis, but must be tightly controlled to prevent tumorigenesis. Here they show that the aryl hydrocarbon receptor is required to terminate the regenerative
Externí odkaz:
https://doaj.org/article/d87470825f124e199a008a818ff3399e
Autor:
Deendyal Bhurta, Sandip B. Bharate
Publikováno v:
ACS Omega. 8:1291-1300
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77baf5396114ed31eca54072e45ec98c
https://doi.org/10.1021/acsomega.2c06733
https://doi.org/10.1021/acsomega.2c06733
Autor:
Sandip B. Bharate, Deendyal Bhurta
Publikováno v:
Medicinal Research Reviews. 42:654-709
Kinases have gained an important place in the list of vital therapeutic targets because of their overwhelming clinical success in the last two decades. Among various clinically validated kinases, the cyclin-dependent kinases (CDK) are one of the exte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e89f63c68f2e0d2450a9a26113be0241
https://doi.org/10.1002/med.21856
https://doi.org/10.1002/med.21856
Autor:
Abubakar Wani, Dilip M. Mondhe, Mubashir J. Mintoo, Sameer U. Khan, Sandip B. Bharate, Deendyal Bhurta, Fayaz Malik, Sumera Banu Malik
Publikováno v:
Molecular Carcinogenesis. 60:671-683
Rohitukine, a chromone alkaloid extracted from Dysoxylum binectariferum, has a propitious anticancer activity. Our previous study shows that a new Rohitukine derivative IIIM-290 restricts the growth of pancreatic cancer in vivo and in vitro. In the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31c5298d9e1096085e9a67b0151c0103
https://doi.org/10.1002/mc.23332
https://doi.org/10.1002/mc.23332
Publikováno v:
Archiv der PharmazieREFERENCES. 355(9)
2,4-Thiazolidinedione (2,4-TZD), commonly known as glitazone, is a ubiquitous heterocyclic pharmacophore possessing a plethora of pharmacological activities and offering a vast opportunity for structural modification. The diverse range of biological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7679baf2212c07988f2d82801aa1dd0c
https://pubmed.ncbi.nlm.nih.gov/35839460
https://pubmed.ncbi.nlm.nih.gov/35839460
Autor:
Deendyal Bhurta, Sandip B. Bharate
Publikováno v:
ChemMedChem. 17(7)
The styryl (Ph-CH=CH-R) group is widely represented in medicinally important compounds, including drugs, clinical candidates, and molecular probes as it positively impacts the lipophilicity, oral absorption, and biological activity. The analysis of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b63120792114c3b99a8518bd89c9689d
https://pubmed.ncbi.nlm.nih.gov/35166041
https://pubmed.ncbi.nlm.nih.gov/35166041
Publikováno v:
Archiv der Pharmazie. 355:2270016
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::461e48349f7a8ca2963b150267e38bff
https://doi.org/10.1002/ardp.202270016
https://doi.org/10.1002/ardp.202270016
Autor:
Sumit G. Gandhi, Mehak Gupta, Vikas Kumar, Sundeep Jaglan, Deepika Singh, Sonali S. Bharate, Ajay Kumar, Sandip B. Bharate, Ram A. Vishwakarma, Deendyal Bhurta
Publikováno v:
Journal of ethnopharmacology. 254
Ethnopharmacological relevance Rheumatoid arthritis is a chronic inflammatory disease of joints. Dysoxylum binectariferum Hook.f (Family: Meliaceae) is a Indian medicinal plant which is traditionally being used to heal inflammation of joints. Aim of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f650793bb826441d3c415b859f131867
https://pubmed.ncbi.nlm.nih.gov/32165175
https://pubmed.ncbi.nlm.nih.gov/32165175
Autor:
Vikas Kumar, Sonali S. Bharate, Puneet Kumar, Ankita Sharma, Sandip B. Bharate, Ram A. Vishwakarma, Deendyal Bhurta
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 166
IIIM-290, an orally bioavailable preclinical candidate is effective in human xenograft models of leukemia, colon and pancreatic cancer. The promising preclinical data of this lead candidate has shown its potential for clinical development. As a part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab29490d2ccbb6522b3a8abe03e1860
https://pubmed.ncbi.nlm.nih.gov/30590350
https://pubmed.ncbi.nlm.nih.gov/30590350
Autor:
Vikramdeep Monga, Sridhar S.N.C., Dharmvir Kantiwal, Ginson George, Atish T. Paul, Deendyal Bhurta
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(16)
A series of novel diaryl substituted pyrazolyl 2,4-thiazolidinediones were synthesized via reaction of appropriate pyrazolecarboxaldehydes with 2,4-thiazolidinedione (TZD) and nitrobenzyl substituted 2,4-thiazolidinedione. The resulting compounds wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df5d2fe49e87e1f2981f682a30fc99b3
https://pubmed.ncbi.nlm.nih.gov/28705641
https://pubmed.ncbi.nlm.nih.gov/28705641