Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Deena V. Soni"'
Autor:
Karlene A. Cimprich, Steven C. Miller, Jayne Hesley, Renee D. Paulsen, Deena V. Soni, Muh-Ching Yee, David E. Solow-Cordero, Tobias Meyer, Roy Wollman, Angela T. Hahn, Anna Guan, Evan F. Cromwell
Publikováno v:
Molecular Cell. 35(2):228-239
Signaling pathways that respond to DNA damage are essential for the maintenance of genome stability and are linked to many diseases, including cancer. Here, a genome-wide siRNA screen was employed to identify additional genes involved in genome stabi
Publikováno v:
Cell Cycle. 7:1285-1300
Cyclin B1 should have some rate limiting function for cell cycle progression. To test this, we measured the effect of siRNA-mediated depletion of cyclin B1 on mitotic entry and timing. We depleted cyclin B1 in HeLa and hTert-RPE1 cells to levels equi
Autor:
Tammy Stefan, Keith Shults, Deena V. Soni, James W. Jacobberger, R. Michael Sramkoski, Phyllis S. Frisa
Publikováno v:
Cytometry Part A. :5-15
Many epitopes are phosphorylated during mitosis. These epitopes are useful biomarkers for mitotic cells. The most commonly used are MPM-2 and serine 10 of histone H3. Here we investigated the use of an antibody generated against a phospho peptide mat
Autor:
Deena V. Soni, James W. Jacobberger
Publikováno v:
Cell Cycle. 3:347-355
Current models suggest that cyclin B1/cdk1 regulates the G2 to M transition and that its activity is maximal during the period from prophase to metaphase in mammalian cells. Although data are lacking, the idea that cyclin B1/cdk1 regulates the transi
Autor:
Deena V, Soni, James W, Jacobberger
Publikováno v:
Cell cycle (Georgetown, Tex.). 3(3)
Current models suggest that cyclin B1/cdk1 regulates the G2 to M transition and that its activity is maximal during the period from prophase to metaphase in mammalian cells. Although data are lacking, the idea that cyclin B1/cdk1 regulates the transi
Autor:
Muh-Ching Yee, Ryan D. Bomgarden, Karlene A. Cimprich, James M. Ford, Patrick J. Lupardus, Deena V. Soni
Publikováno v:
The EMBO Journal. 25:5036-5036
An essential component of the ATR (ataxia telangiectasia-mutated and Rad3-related)-activating structure is single-stranded DNA. It has been suggested that nucleotide excision repair (NER) can lead to activation of ATR by generating such a signal, and