Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Deena Jalal"'
Autor:
Fatma S. Mohamed, Deena Jalal, Youssef M. Fadel, Samir F. El-Mashtoly, Wael Z. Khaled, Ahmed A. Sayed, Mohamed A. Ghazy
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Wilms tumor (WT) is a pediatric kidney cancer associated with poor outcomes in patients with unfavorable histological features such as anaplasia. Small non-coding RNAs, such as miRNAs, are known to be involved in WT pathogenesis. However, research on
Externí odkaz:
https://doaj.org/article/ea2b2010c30f461f99fc5f9eab99fe1d
Genomic characterization of SARS-CoV-2 in Egypt: insights into spike protein thermodynamic stability
Autor:
Deena Jalal, Omar Samir, Mariam G. Elzayat, Hend E. El-Shqanqery, Aya A. Diab, Lamiaa ElKaialy, Aya M. Mohammed, Donia Hamdy, Islam K. Matar, Khaled Amer, Mostafa Elnakib, Wael Hassan, Tarek Mansour, Sonia Soliman, Reem Hassan, Ghada M. Al-Toukhy, Mahmoud Hammad, Ibrahim Abdo, Ahmed A. Sayed
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
The overall pattern of the SARS-CoV-2 pandemic so far has been a series of waves; surges in new cases followed by declines. The appearance of novel mutations and variants underlie the rises in infections, making surveillance of SARS-CoV-2 mutations a
Externí odkaz:
https://doaj.org/article/5f072f9dc35e45f8b47040851b0f5757
Autor:
Deena Jalal, Mariam G. Elzayat, Hend E. El-Shqanqery, Aya A. Diab, Abdelrahman Yahia, Omar Samir, Usama Bakry, Khaled Amer, Mostafa ElNaqeeb, Wael Hassan, Hala S. Talat, Hala M. Farawela, Mona S. Hamdy, May S. Soliman, Maha H. El Sissy, Moushira H. Ezzelarab, Sara M. El khateeb, Lamyaa H. Soliman, Sara E. Haddad, Ashraf Hatem, Mohamed S. Ismail, Maha Hossam, Tarek Mansour, Lobna Shalaby, Sonia Soliman, Reem Hassan, Mahmoud Hammad, Ibrahim Abdo, Sameh Magdeldin, Alaa ElHaddad, Sherif Abouelnaga, Ahmed A. Sayed
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract A serious global public health emergency emerged late November 2019 in Wuhan City, China, by a new highly pathogenic virus, SARS-CoV-2. The virus evolution spread has been tracked by three developing databases: GISAID, Nextstrain and PANGO t
Externí odkaz:
https://doaj.org/article/e8f154c00e2c476f924a0692b018394e
Autor:
Deena Jalal, Mariam G. Elzayat, Aya A. Diab, Hend E. El-Shqanqery, Omar Samir, Usama Bakry, Reem Hassan, Mervat Elanany, Lobna Shalaby, Ahmed A. Sayed
Publikováno v:
mSphere, Vol 6, Iss 6 (2021)
ABSTRACT Infection by multidrug-resistant (MDR) Acinetobacter baumannii is one of the major causes of hospital-acquired infections worldwide. The ability of A. baumannii to survive in adverse conditions as well as its extensive antimicrobial resistan
Externí odkaz:
https://doaj.org/article/be195fbd07fc4faa9cd0bf817577bf71
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
The endogenous yeast 2-μm plasmid while innocuous to the host, needs to be properly regulated to avoid a toxic increase in copy number. The plasmid copy number control system is under the control of the plasmid encoded recombinase, Flp1. In case of
Externí odkaz:
https://doaj.org/article/331edc3d867d436fa529f5bc8a027423
Autor:
Lobna Shalaby, Usama Bakry, Deena Jalal, Ahmed A. Sayed, Aya A. Diab, Omar Samir, Hend E El-Shqanqery, Mervat Elanany, Mariam G Elzayat, Reem Mostafa Hassan
Publikováno v:
mSphere
mSphere, Vol 6, Iss 6 (2021)
mSphere, Vol 6, Iss 6 (2021)
Infection by multidrug-resistant (MDR) Acinetobacter baumannii is one of the major causes of hospital-acquired infections worldwide. The ability of A. baumannii to survive in adverse conditions as well as its extensive antimicrobial resistance make i
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences
The endogenous yeast 2-μm plasmid while innocuous to the host, needs to be properly regulated to avoid a toxic increase in copy number. The plasmid copy number control system is under the control of the plasmid encoded recombinase, Flp1. In case of
Publikováno v:
DNA repair. 97
DNA double-strand breaks (DSBs) constitute one of the most cytotoxic forms of DNA damage and pose a significant threat to cell viability, survival, and homeostasis. DSBs have the potential to promote aneuploidy, cell death and potentially deleterious
Publikováno v:
DNA Repair. 51:2-13
Malfunction of enzymes that detoxify reactive oxygen species leads to oxidative attack on biomolecules including DNA and consequently activates various DNA repair pathways. The nature of DNA damage and the cell cycle stage at which DNA damage occurs
Publikováno v:
Nucleic Acids Research
The genome of the cell is often exposed to DNA damaging agents and therefore requires an intricate well-regulated DNA damage response (DDR) to overcome its deleterious effects. The DDR needs proper regulation for its timely activation, repression, as