Zobrazeno 1 - 10
of 483
pro vyhledávání: '"Deena, S."'
Autor:
Hesham, Heba M., Dokla, Eman M.E., Elrazaz, Eman Z., Lasheen, Deena S., Abou El Ella, Dalal A.
Publikováno v:
In European Journal of Medicinal Chemistry 5 November 2024 277
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-18 (2024)
Abstract Several novel approaches to target Bcl-2 proteins and apoptotic pathways have been identified in recent years for the treatment of different types of cancer including colorectal cancer. However, no effective treatments were yet developed for
Externí odkaz:
https://doaj.org/article/388da09d7a354eea83defb98401e2f6e
Autor:
Moftah, Hadeer K., Mousa, Mai H.A., Elrazaz, Eman Z., Kamel, Ahmed S., Lasheen, Deena S., Georgey, Hanan H.
Publikováno v:
In Bioorganic Chemistry February 2024 143
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Apoptosis plays a crucial role in cancer pathogenesis and drug resistance. BCL-2 family of enzymes is considered as one of the key enzymes which is involved in apoptosis. When there is disruption in the balance between anti-apoptotic and pro
Externí odkaz:
https://doaj.org/article/7799bdd8830344998faf81ccd4ff8a1c
Autor:
Deena, S., Vedanayaki, S., Sathish, T., Dao, My Uyen, Rajasimman, M., Saravanan, R., Prakash, P.
Publikováno v:
In Environmental Research 1 January 2023 216 Part 4
Autor:
Abeer H. A. Abdelhafiz, Rabah A. T. Serya, Deena S. Lasheen, Nessa Wang, Mansour Sobeh, Michael Wink, Khaled A. M. Abouzid
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2710-2724 (2022)
Multidrug resistance (MDR) is a leading cause for treatment failure in cancer patients. One of the reasons of MDR is drug efflux by ATP-binding cassette (ABC) transporters in eukaryotic cells especially ABCB1 (P-glycoprotein). In this study, certain
Externí odkaz:
https://doaj.org/article/57eeea20c5b242c7b876f7be7406cf6f
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 315-332 (2022)
Cancer is one of the most aggressive diseases characterised by abnormal growth and uncontrolled cell division. PI3K is a lipid kinase involved in cancer progression which makes it fruitful target for cancer control. 28 new morpholine based thieno[2,3
Externí odkaz:
https://doaj.org/article/9a8d84d5b8a74cfb849e85697867fe18
Akademický článek
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Akademický článek
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Autor:
Eldeeb, Assem H., Abo-Ashour, Mahmoud F., Angeli, Andrea, Bonardi, Alessandro, Lasheen, Deena S., Elrazaz, Eman Z., Nocentini, Alessio, Gratteri, Paola, Abdel-Aziz, Hatem A., Supuran, Claudiu T.
Publikováno v:
In European Journal of Medicinal Chemistry 5 October 2021 221