Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Deelan Doolabh"'
Autor:
Sarah B Joseph, Melissa-Rose Abrahams, Matthew Moeser, Lynn Tyers, Nancie M Archin, Olivia D Council, Amy Sondgeroth, Ean Spielvogel, Ann Emery, Shuntai Zhou, Deelan Doolabh, Sherazaan D Ismail, Salim Abdool Karim, David M Margolis, Sergei Kosakovsky Pond, Nigel Garrett, Ronald Swanstrom, Carolyn Williamson
Publikováno v:
PLoS Pathogens, Vol 20, Iss 2, p e1011974 (2024)
People with HIV-1 (PWH) on antiretroviral therapy (ART) can maintain undetectable virus levels, but a small pool of infected cells persists. This pool is largely comprised of defective proviruses that may produce HIV-1 proteins but are incapable of m
Externí odkaz:
https://doaj.org/article/7fa9d4a490f64aa4ab74aa4822d66bd9
Autor:
Hannah Hussey, Mary-Ann Davies, Alexa Heekes, Carolyn Williamson, Ziyaad Valley-Omar, Diana Hardie, Stephen Korsman, Deelan Doolabh, Wolfgang Preiser, Tongai Maponga, Arash Iranzadeh, Sean Wasserman, Linda Boloko, Greg Symons, Peter Raubenheimer, Arifa Parker, Neshaad Schrueder, Wesley Solomon, Petro Rousseau, Nicole Wolter, Waasila Jassat, Cheryl Cohen, Richard Lessells, Robert J Wilkinson, Andrew Boulle, Nei-yuan Hsiao
Publikováno v:
International Journal of Infectious Diseases, Vol 118, Iss , Pp 150-154 (2022)
Background: At present, it is unclear whether the extent of reduced risk of severe disease seen with SARS-Cov-2 Omicron variant infection is caused by a decrease in variant virulence or by higher levels of population immunity. Methods: RdRp target de
Externí odkaz:
https://doaj.org/article/0ed48b6a10ed48b8b3ecf83752f493b6
Autor:
Hannah Hussey, Mary-Ann Davies, Carolyn Williamson, Alexa Heekes, Diana Hardie, Ziyaad Valley-Omar, Deelan Doolabh, Stephen Korsman, Tongai Maponga, Wofgang Preiser, Susan Engelbrecht, Arash Iranzadeh, Neshaad Schrueder, Sean Wasserman, Greg Symons, Linda Boloko, Abraham Viljoen, Peter Raubenheimer, Cheryl Cohen, Arifa Parker, Richard Lessells, Waasila Jasat, Andrew Boulle, Robert J Wilkinson, Marvin Hsiao
Publikováno v:
Gates Open Research, Vol 6 (2022)
Background: The SARS-CoV-2 Delta variant (B.1.617.2) has been associated with more severe disease, particularly when compared to the Alpha variant. Most of this data, however, is from high income countries and less is understood about the variant’s
Externí odkaz:
https://doaj.org/article/af14ea6f381d4ee787695e0087df0d09
Autor:
Hannah Hussey, Mary-Ann Davies, Alexa Heekes, Carolyn Williamson, Ziyaad Valley-Omar, Diana Hardie, Stephen Korsman, Deelan Doolabh, Wofgang Preiser, Tongai Maponga, Arash Iranzadeh, Susan Engelbrecht, Sean Wasserman, Neshaad Schrueder, Linda Boloko, Greg Symons, Peter Raubenheimer, Abraham Viljoen, Arifa Parker, Cheryl Cohen, Waasila Jasat, Richard Lessells, Robert J Wilkinson, Andrew Boulle, Marvin Hsiao
Background: The SARS-CoV-2 Delta variant (B.1.617.2) has been associated with more severe disease, particularly when compared to the Alpha variant. Most of this data, however, is from high income countries and less is understood about the variant’s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ac2bc16dd70443cd9bbd9b5731d1cc8
http://hdl.handle.net/10044/1/100646
http://hdl.handle.net/10044/1/100646
Autor:
Travis Sanders, David Gelagay, Deelan Doolabh, Lee French, Jennifer Pavlica, Julie Walker, Clara Ross, Kailee Reed, Thomas Harrison, Ross Wadsworth, Eric van der Walt, Brian Kudlow
Publikováno v:
Cancer Research. 83:242-242
mRNA sequencing via poly(A) selection is a widely used and highly useful tool for molecular profiling but has limitations in the oncology space. The template damage of RNA extracted from formalin-fixed, paraffin-embedded (FFPE) material results in 5
Autor:
B.T. Sewell, Darren P. Martin, José Lourenço, Marta Giovanetti, Sureshnee Pillay, Luiz Carlos Junior Alcantara, Richard J Lessells, Shareef Abrahams, Tulio de Oliveira, Arash Iranzadeh, Sergei L Kosakovsky Pond, Emmanuel James San, Wolfgang Preiser, Arshad Ismail, Anne von Gottberg, Houriiyah Tegally, Vagner Fonseca, Diana Hardie, Mushal Allam, Stephen N.J. Korsman, Deelan Doolabh, Alex Sigal, Koleka Mlisana, Nokukhanya Msomi, Mary-Ann Davies, Eduan Wilkinson, Gert U. van Zyl, Dominique Goedhals, Arghavan Alisoltani-Dehkordi, Caroline Maslo, Francesco Petruccione, Gert Marais, Constantinos Kurt Wibmer, Sibongile Walaza, Oluwakemi Laguda-Akingba, Steven Weaver, Carolyn Williamson, Susan Engelbrecht, Denis York, Jinal N. Bhiman, Innocent Mudau, Thabo Mohale, Lynn Tyers, Jennifer Giandhari, Adam Godzik, Allison J. Glass, Nei yuan Hsiao
Publikováno v:
Nature
Continued uncontrolled transmission of SARS-CoV-2 in many parts of the world is creating conditions for substantial evolutionary changes to the virus1,2. Here we describe a newly arisen lineage of SARS-CoV-2 (designated 501Y.V2; also known as B.1.351
Autor:
Gert Marais, Nei-yuan Hsiao, Arash Iranzadeh, Deelan Doolabh, Rageema Joseph, Annabel Enoch, Chun-yat Chu, Carolyn Williamson, Adrian Brink, Diana Hardie
Publikováno v:
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology. 152
The Omicron variant of concern is characterised by more than 50 distinct mutations, most in the spike protein. The implications of these for disease transmission, tissue tropism and diagnostic testing needs study.We evaluated the performance of RT-PC
Autor:
Raquel Viana, Sikhulile Moyo, Daniel G. Amoako, Houriiyah Tegally, Cathrine Scheepers, Christian L. Althaus, Ugochukwu J. Anyaneji, Phillip A. Bester, Maciej F. Boni, Mohammed Chand, Wonderful T. Choga, Rachel Colquhoun, Michaela Davids, Koen Deforche, Deelan Doolabh, Louis du Plessis, Susan Engelbrecht, Josie Everatt, Jennifer Giandhari, Marta Giovanetti, Diana Hardie, Verity Hill, Nei-Yuan Hsiao, Arash Iranzadeh, Arshad Ismail, Charity Joseph, Rageema Joseph, Legodile Koopile, Sergei L. Kosakovsky Pond, Moritz U. G. Kraemer, Lesego Kuate-Lere, Oluwakemi Laguda-Akingba, Onalethatha Lesetedi-Mafoko, Richard J. Lessells, Shahin Lockman, Alexander G. Lucaci, Arisha Maharaj, Boitshoko Mahlangu, Tongai Maponga, Kamela Mahlakwane, Zinhle Makatini, Gert Marais, Dorcas Maruapula, Kereng Masupu, Mogomotsi Matshaba, Simnikiwe Mayaphi, Nokuzola Mbhele, Mpaphi B. Mbulawa, Adriano Mendes, Koleka Mlisana, Anele Mnguni, Thabo Mohale, Monika Moir, Kgomotso Moruisi, Mosepele Mosepele, Gerald Motsatsi, Modisa S. Motswaledi, Thongbotho Mphoyakgosi, Nokukhanya Msomi, Peter N. Mwangi, Yeshnee Naidoo, Noxolo Ntuli, Martin Nyaga, Lucier Olubayo, Sureshnee Pillay, Botshelo Radibe, Yajna Ramphal, Upasana Ramphal, James E. San, Lesley Scott, Roger Shapiro, Lavanya Singh, Pamela Smith-Lawrence, Wendy Stevens, Amy Strydom, Kathleen Subramoney, Naume Tebeila, Derek Tshiabuila, Joseph Tsui, Stephanie van Wyk, Steven Weaver, Constantinos K. Wibmer, Eduan Wilkinson, Nicole Wolter, Alexander E. Zarebski, Boitumelo Zuze, Dominique Goedhals, Wolfgang Preiser, Florette Treurnicht, Marietje Venter, Carolyn Williamson, Oliver G. Pybus, Jinal Bhiman, Allison Glass, Darren P. Martin, Andrew Rambaut, Simani Gaseitsiwe, Anne von Gottberg, Tulio de Oliveira
Publikováno v:
Viana, R, Moyo, S, Amoako, D G, Tegally, H, Scheepers, C, Althaus, C L, Anyaneji, U J, Bester, P A, Boni, M F, Chand, M, Choga, W T, Colquhoun, R, Davids, M, Deforche, K, Doolabh, D, du Plessis, L, Engelbrecht, S, Everatt, J, Giandhari, J, Giovanetti, M, Hardie, D, Hill, V, Hsiao, N Y, Iranzadeh, A, Ismail, A, Joseph, C, Joseph, R, Koopile, L, Kosakovsky Pond, S L, Kraemer, M U G, Kuate-Lere, L, Laguda-Akingba, O, Lesetedi-Mafoko, O, Lessells, R J, Lockman, S, Lucaci, A G, Maharaj, A, Mahlangu, B, Maponga, T, Mahlakwane, K, Makatini, Z, Marais, G, Maruapula, D, Masupu, K, Matshaba, M, Mayaphi, S, Mbhele, N, Mbulawa, M B, Mendes, A, Mlisana, K, Mnguni, A, Mohale, T, Moir, M, Moruisi, K, Mosepele, M, Motsatsi, G, Motswaledi, M S, Mphoyakgosi, T, Msomi, N, Mwangi, P N, Naidoo, Y, Ntuli, N, Nyaga, M, Olubayo, L, Pillay, S, Radibe, B, Ramphal, Y, Ramphal, U, San, J E, Scott, L, Shapiro, R, Singh, L, Smith-Lawrence, P, Stevens, W, Strydom, A, Subramoney, K, Tebeila, N, Tshiabuila, D, Tsui, J, van Wyk, S, Weaver, S, Wibmer, C K, Wilkinson, E, Wolter, N, Zarebski, A E, Zuze, B, Goedhals, D, Preiser, W, Treurnicht, F, Venter, M, Williamson, C, Pybus, O G, Bhiman, J, Glass, A, Martin, D P, Rambaut, A, Gaseitsiwe, S, von Gottberg, A & de Oliveira, T 2022, ' Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa ', Nature, vol. 603, pp. 679-686 . https://doi.org/10.1038/s41586-022-04411-y
Viana, Raquel; Moyo, Sikhulile; Amoako, Daniel G; Tegally, Houriiyah; Scheepers, Cathrine; Althaus, Christian L.; Anyaneji, Ugochukwu J; Bester, Phillip A; Boni, Maciej F; Chand, Mohammed; Choga, Wonderful T; Colquhoun, Rachel; Davids, Michaela; Deforche, Koen; Doolabh, Deelan; du Plessis, Louis; Engelbrecht, Susan; Everatt, Josie; Giandhari, Jennifer; Giovanetti, Marta; ... (2022). Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa. Nature, 603(7902), pp. 679-686. Macmillan Journals Ltd. 10.1038/s41586-022-04411-y
Viana, Raquel; Moyo, Sikhulile; Amoako, Daniel G; Tegally, Houriiyah; Scheepers, Cathrine; Althaus, Christian L.; Anyaneji, Ugochukwu J; Bester, Phillip A; Boni, Maciej F; Chand, Mohammed; Choga, Wonderful T; Colquhoun, Rachel; Davids, Michaela; Deforche, Koen; Doolabh, Deelan; du Plessis, Louis; Engelbrecht, Susan; Everatt, Josie; Giandhari, Jennifer; Giovanetti, Marta; ... (2022). Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa. Nature, 603(7902), pp. 679-686. Macmillan Journals Ltd. 10.1038/s41586-022-04411-y
The SARS-CoV-2 epidemic in southern Africa has been characterized by three distinct waves. The first was associated with a mix of SARS-CoV-2 lineages, while the second and third waves were driven by the Beta (B.1.351) and Delta (B.1.617.2) variants,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c6c563423c1f4fc3d81e94434f6612c
https://www.pure.ed.ac.uk/ws/files/257854234/s41586_022_04411_y.pdf
https://www.pure.ed.ac.uk/ws/files/257854234/s41586_022_04411_y.pdf
Autor:
Gert Marais, Nei-yuan Hsiao, Arash Iranzadeh, Deelan Doolabh, Annabel Enoch, Chun-yat Chu, Carolyn Williamson, Adrian Brink, Diana Hardie
The Omicron variant is characterised by more than 50 distinct mutations, the majority of which are located in the spike protein. The implications of these mutations for disease transmission, tissue tropism and diagnostic testing are still to be deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7e111f2f981d47a8eb5852861c2f4b8
https://doi.org/10.1101/2021.12.22.21268246
https://doi.org/10.1101/2021.12.22.21268246
Autor:
Catherine, Riou, Roanne, Keeton, Thandeka, Moyo-Gwete, Tandile, Hermanus, Prudence, Kgagudi, Richard, Baguma, Ziyaad, Valley-Omar, Mikhail, Smith, Houriiyah, Tegally, Deelan, Doolabh, Arash, Iranzadeh, Lynn, Tyers, Hygon, Mutavhatsindi, Marius B, Tincho, Ntombi, Benede, Gert, Marais, Lionel R, Chinhoyi, Mathilda, Mennen, Sango, Skelem, Elsa, du Bruyn, Cari, Stek, Tulio, de Oliveira, Carolyn, Williamson, Penny L, Moore, Robert J, Wilkinson, Ntobeko A B, Ntusi, Wendy A, Burgers
Publikováno v:
Science translational medicine. 14(631)
SARS-CoV-2 variants that escape neutralization and potentially affect vaccine efficacy have emerged. T cell responses play a role in protection from reinfection and severe disease, but the potential for spike mutations to affect T cell immunity is in