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Early Diagnosis of Renal Tubular Dysfunction in HIV-Infected Patients; a Case of Interleukin (IL)-18 and other Common Indicators of Renal Toxicity

Autor: Deebii N, EP Odum, Oko-jaja Ri, Tamuno I, Okerengwo Aa, Obunge Ok, CG Orluwene

Publikováno v: Immunotherapy: Open Access.

Background: At present renal dysfunction in clinical practice is measured using serum creatinine values to calculate eGFR (estimated glomerular filtration rate) but creatinine is a late marker of renal dysfunction and is only raised when up to 30-50%

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ed525243ab8c4714db4d5de038692c75
https://doi.org/10.4172/2471-9552.1000118

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Urinary Interleukin (Il)-18 as an Early Predictive Biomarker of Subclinical Proximal Tubular Dysfunction in HIV-Infected Patients Exposed to Tenofovir

Autor: Deebii N, CG Orluwene, EP Odum

Publikováno v: Journal of AIDS & Clinical Research.

Proximal tubular dysfunction (PTD) is a frequent complication of HIV-infected patients and lack of early biomarkers for PTD has impaired our ability to intervene in a timely manner. In this present study, we tested if interleukin- 18 (IL-18) is a pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1d659cabbd206ade4162b49caa250369
https://doi.org/10.4172/2155-6113.1000497

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