Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Dee N. Dao"'
Autor:
Dhinakaran Sambandan, Dee N. Dao, Brian C. Weinrick, Catherine Vilchèze, Sudagar S. Gurcha, Anil Ojha, Laurent Kremer, Gurdyal S. Besra, Graham F. Hatfull, William R. Jacobs
Publikováno v:
mBio, Vol 4, Iss 3 (2013)
ABSTRACT The chronic nature of tuberculosis (TB), its requirement of long duration of treatment, its ability to evade immune intervention, and its propensity to relapse after drug treatment is discontinued are reminiscent of other chronic, biofilm-as
Externí odkaz:
https://doaj.org/article/0e4ca69911e645169334c63c251a3526
Publikováno v:
Virulence Mechanisms of Bacterial Pathogens. :31-50
This chapter explores the genetic toolbox available for the study of Mycobacterium tuberculosis physiology, the immunology relating to M. tuberculosis infection, and relevant animal models to probe the corresponding disease course. The development of
Autor:
Sudagar S. Gurcha, Anil K. Ojha, Dee N. Dao, Laurent Kremer, Dhinakaran Sambandan, Catherine Vilchèze, Gurdyal S. Besra, Brian Weinrick, Graham F. Hatfull, William R. Jacobs
Publikováno v:
mBio, Vol 4, Iss 3 (2013)
mBio
mBio
The chronic nature of tuberculosis (TB), its requirement of long duration of treatment, its ability to evade immune intervention, and its propensity to relapse after drug treatment is discontinued are reminiscent of other chronic, biofilm-associated
Autor:
Manjunatha M. Venkataswamy, Tsungda Hsu, Diane J. Ordway, Marcela Henao-Tamayo, William R. Jacobs, Paras Jain, Rani S. Sellers, Michael F. Goldberg, Dee N. Dao, John Chan, Kari Sweeney, Bing Chen, John Kim, Regy Lukose, Mei Chen, Steven A. Porcelli, Ian M. Orme
Publikováno v:
Nature medicine. 17(10)
We report the involvement of an evolutionarily conserved set of mycobacterial genes, the esx-3 region, in evasion of bacterial killing by innate immunity. Whereas high-dose intravenous infections of mice with the rapidly growing mycobacterial species
Autor:
Dee N Dao, Kari Sweeney, Tsungda Hsu, Sudagar S Gurcha, Ivan P Nascimento, Dan Roshevsky, Gurdyal S Besra, John Chan, Steven A Porcelli, William R Jacobs
Publikováno v:
PLoS Pathogens, Vol 4, Iss 6, p e1000081 (2008)
PLoS Pathogens
PLoS Pathogens
Mycobacterium tuberculosis has evolved many strategies to evade elimination by the host immune system, including the selective repression of macrophage IL-12p40 production. To identify the M. tuberculosis genes responsible for this aspect of immune e
Publikováno v:
Microbiology (Reading, England). 146
Using a selection for Dictyostelium mutants that preferentially form spores, we have recovered a mutant called CheaterA. In chimeras with isogenic wild-type cells, the CheaterA mutant preferentially forms viable spores rather than inviable stalk cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633d8a1efb8ca382b6724e493bb5088e
https://europepmc.org/articles/PMC16232/
https://europepmc.org/articles/PMC16232/
Publikováno v:
Stroke. 22(10)
Glutamate has been implicated in the pathophysiology of acute hypoxic-ischemic encephalopathy. Glutamine synthetase is an enzyme found in astrocytes that converts glutamate to its nontoxic analogue, glutamine. The present study tests the hypothesis t
Publikováno v:
Protist; Oct2003, Vol. 154 Issue 3/4, p419, 11p