Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Dedmer, Schaafsma"'
Autor:
Seyed Fazel Nabavi, Solomon Habtemariam, Ioana Berindan-Neagoe, Cosmin Andrei Cismaru, Dedmer Schaafsma, Saeid Ghavami, Maciej Banach, Safieh Aghaabdollahian, Seyed Mohammad Nabavi
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 2, Pp 431-433 (2021)
Externí odkaz:
https://doaj.org/article/38105cf2829f496fbcdcf4331547183a
Autor:
Abbas Afkhami, Shahla Shojaei, Mazaher Ahmadi, Marek Los, Parvaneh Mehrbod, Tayyebeh Madrakian, Hagar I. Labouta, Pooneh Mokarram, Dedmer Schaafsma, Nahid Rezvani Jalal, Michael Giersig, Saeid Ghavami
Publikováno v:
ACS Applied Nano Materials. 4:4307-4328
Magnetic nanomaterials (MNMs) have gained great interest from different fields of study ranging from wastewater treatment to (bio)sensor development, taking advantage of both nanoscale size (allowing high surface-to-volume ratios) and the opportunity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edd3fcd04edb3e045525453b93350bf8
https://doi.org/10.1021/acsanm.1c01077
https://doi.org/10.1021/acsanm.1c01077
Autor:
Kaveh Baghaei, Sogol Mazhari, Samaneh Tokhanbigli, Gilda Parsamanesh, Helia Alavifard, Dedmer Schaafsma, Saeid Ghavami
Publikováno v:
Drug discovery today. 27(4)
Hepatic fibrosis is a manifestation of different etiologies of liver disease with the involvement of multiple mediators in complex network interactions. Activated hepatic stellate cells (aHSCs) are the central driver of hepatic fibrosis, given their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd1cae63b113e456268b14bddeeb618
https://pubmed.ncbi.nlm.nih.gov/34952225
https://pubmed.ncbi.nlm.nih.gov/34952225
Autor:
Seyed Mohammad Nabavi, Dedmer Schaafsma, Seyed Fazel Nabavi, Solomon Habtemariam, Cosmin Andrei Cismaru, Saeid Ghavami, Maciej Banach, Ioana Berindan-Neagoe
Publikováno v:
Journal of Cellular and Molecular Medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a31a484da1f21bc556d1371426bf13a
https://doi.org/10.1111/jcmm.15652
https://doi.org/10.1111/jcmm.15652
Publikováno v:
Pharmacologytherapeutics. 228
Fibrosis is defined by excessive formation and accumulation of extracellular matrix proteins, produced by myofibroblasts, that supersedes normal wound healing responses to injury and results in progressive architectural remodelling. Fibrosis is often
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bae10fb46d6ff572f30c5edc42ca8d4
https://pubmed.ncbi.nlm.nih.gov/34171336
https://pubmed.ncbi.nlm.nih.gov/34171336
Autor:
Saeid Ghavami, Mark M Mutawe, Pawan Sharma, Behzad Yeganeh, Karol D McNeill, Thomas Klonisch, Helmut Unruh, Hessam H Kashani, Dedmer Schaafsma, Marek Los, Andrew J Halayko
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16523 (2011)
Statins inhibit the proximal steps of cholesterol biosynthesis, and are linked to health benefits in various conditions, including cancer and lung disease. We have previously investigated apoptotic pathways triggered by statins in airway mesenchymal
Externí odkaz:
https://doaj.org/article/355b8c38925742648fe47238996f5963
Autor:
Tayyebeh Madrakian, Shahla Shojaei, Dedmer Schaafsma, Javad Alizadeh, Reza Mahdian, Jakub Rosik, Simone C. da Silva Rosa, Shayan Amiri, Filip Machaj, Stevan Pecic, Saeid Ghavami, Marek J. Łos, Mazaher Ahmadi, Amir A. Zeki
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1866:165968
The statin drugs ('statins') potently inhibit hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase by competitively blocking the active site of the enzyme. Statins decrease de novo cholesterol biosynthesis and thereby reduce plasma cholesterol levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe35b1592343b9c2ceba505190f90991
https://doi.org/10.1016/j.bbadis.2020.165968
https://doi.org/10.1016/j.bbadis.2020.165968
Autor:
Dedmer Schaafsma, Klaudia Kaczmarek, Patricia Ramos-Ramírez, Yassine Amrani, Omar Tliba, Reynold A. Panettieri
Publikováno v:
Pharmacol Ther
Glucocorticoids (GCs) are the treatment of choice for chronic inflammatory diseases such as asthma. Despite proven effective anti-inflammatory and immunosuppressive effects, long-term and/or systemic use of GCs can potentially induce adverse effects.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f607733bdd74c307d57f61d2819bc5
https://doi.org/10.1016/j.pharmthera.2020.107589
https://doi.org/10.1016/j.pharmthera.2020.107589
Autor:
Sekaran Saravanan, Zahra Sepehri, Mehnosh Toback, Hassan Marzban, Joseph W. Gordon, Kimia Sheikholeslami, Adel Rezaei Moghadam, Mohammad Hashemi, Jeffrey T. Wigle, Pooneh Mokarram, Anahita Masoom, Mansour Poorebrahim, Davinder S. Jassal, Dedmer Schaafsma, Saeid Ghavami, Michael P. Czubryt, Ian M.C. Dixon, Mohsen Akbari, Matthew R. Zeglinski, Haleh Rokni, Nima Khadem Mohtaram, Sanjiv Dhingra, Niketa Sareen, Sudharsana R. Ande, Pawan K. Singal
Publikováno v:
Comprehensive Physiology
Cardiovascular disease leading to heart failure (HF) remains a leading cause of morbidity and mortality worldwide. Improved pharmacological and interventional coronary procedures have led to improved outcomes following acute myocardial infarction. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a81367b3dcf2661b84346332c2de98
https://pubmed.ncbi.nlm.nih.gov/30549015
https://pubmed.ncbi.nlm.nih.gov/30549015
Autor:
Rennolds S. Ostrom, Reynod A. Panettieri, Yassine Amrani, Cynthia J. Koziol-White, Dedmer Schaafsma, Omar Tliba
Publikováno v:
Trends in pharmacological sciences. 40(1)
Glucocorticoid (GC) anti-inflammatory effects generally require a prolonged onset of action and involve genomic processes. Because of the rapidity of some of the GC effects, however, the concept that non-genomic actions may contribute to GC mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e12097a669e54516c6431169ef9d6f45
https://pubmed.ncbi.nlm.nih.gov/30497693
https://pubmed.ncbi.nlm.nih.gov/30497693