Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Dede N Ekoue"'
Autor:
Emmanuel Ansong, Qi Ying, Dede N Ekoue, Ryan Deaton, Andrew R Hall, Andre Kajdacsy-Balla, Wancai Yang, Peter H Gann, Alan M Diamond
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127295 (2015)
Selenium-Binding Protein 1 (SBP1, SELENBP1, hSP56) is a selenium-associated protein shown to be at lower levels in tumors, and its lower levels are frequently predictive of a poor clinical outcome. Distinguishing indolent from aggressive prostate can
Externí odkaz:
https://doaj.org/article/491d50acecea4c8b977a7c7e5b910602
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93472 (2014)
Glutathione peroxidase activity was previously determined to be elevated in lymphocytes obtained from patients treated with the Bcr-Abl kinase inhibitor imatinib mesylate. In order to expand upon this observation, the established chronic myelogenous
Externí odkaz:
https://doaj.org/article/9519fcc58f42467885e27e1ce7ec5b93
Autor:
RK Vadlamudi, GR Sareddy, Ganesh V. Raj, Mei Kuen Li, Rajeshwar Rao Tekmal, S Ma, J-M Ahn, Mei Zhou, T-K Lee, EM Blatt, Xihui Liu, Suryavathi Viswanadhapalli, Dede N. Ekoue
Publikováno v:
Cancer Research. 79:P4-07
Background: Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer and represents a disproportional share of the breast cancer mortality, primarily due to a lack of targeted therapies. There is a major unmet need for rationall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::395a3d99a270187bbc362b69c972629e
https://doi.org/10.1158/1538-7445.sabcs18-p4-07-01
https://doi.org/10.1158/1538-7445.sabcs18-p4-07-01
Autor:
Larisa Nonn, Lenny Hong, Virgilia Macias, Alan M Diamond, Dede N. Ekoue, Emmanuel Ansong, Andre Kajdacsy-Balla, Peter H. Gann, Ryan Deaton, Rawan Allozi Rupnow
Publikováno v:
Antioxidants, Vol 7, Iss 11, p 167 (2018)
Antioxidants
Volume 7
Issue 11
Antioxidants
Volume 7
Issue 11
Glutathione peroxidase 1 (GPX1) is an extensively studied selenium-dependent protein that reduces hydrogen and lipid peroxides to water. Because of its antioxidant function and its responsiveness to dietary intakes of selenium, an essential trace ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0617eb06dff4940963c8673a7a308a7
https://www.mdpi.com/2076-3921/7/11/167
https://www.mdpi.com/2076-3921/7/11/167
Autor:
Dede N. Ekoue, Alan M Diamond, Li Liu, Vincent L. Freeman, Giovanna Bermano, Janaina L. S. Donadio
Publikováno v:
The Prostate. 79(5)
Background: NKX3.1 is a tumor suppressor frequently lost in prostate cancer. Previous studies by others indicated that the risks associated with reduced NKX3.1 levels can be enhanced by anti-oxidant supplementation. Selenium is an essential component
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9892205c2dbe50853bdb4780cc8b81
https://pubmed.ncbi.nlm.nih.gov/30582190
https://pubmed.ncbi.nlm.nih.gov/30582190
Publikováno v:
Cancer letters. 438
The current therapeutic armamentarium for castration-resistant prostate cancer (CRPC) includes second-generation agents such as the Androgen Receptor (AR) inhibitor enzalutamide and the androgen synthesis inhibitor abiraterone acetate, immunotherapie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd8eaaaf77372284b1db1e5d04a3ce28
https://pubmed.ncbi.nlm.nih.gov/30217566
https://pubmed.ncbi.nlm.nih.gov/30217566
Publikováno v:
Expert review of clinical pharmacology. 11(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a73002510d03e285a3255cc52f84c621
https://pubmed.ncbi.nlm.nih.gov/29439601
https://pubmed.ncbi.nlm.nih.gov/29439601
Autor:
Alan M. Diamond, Virgilia Macias, Ryan Deaton, Li Liu, Larisa Nonn, Vincent L. Freeman, Matthew J. Picklo, Gail S. Prins, Craig Lacher, Andre Kajdacsy-Balla, Peter H. Gann, Emmanuel Ansong, Dede N. Ekoue
Publikováno v:
The Prostate
Background Selenium status is inversely associated with the incidence of prostate cancer. However, supplementation trials have not indicated a benefit of selenium supplementation in reducing cancer risk. Polymorphisms in the gene encoding selenoprote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79f1b9df255c729840450f86946291c1
https://pubmed.ncbi.nlm.nih.gov/29314169
https://pubmed.ncbi.nlm.nih.gov/29314169
Autor:
GR Sareddy, Yiliao Luo, Suryavathi Viswanadhapalli, SE Weintraub, J-M Ahn, S Ma, Carlos L. Arteaga, RK Vadlamudi, Xihui Liu, Prasanna G. Alluri, T-K Lee, Kara Kassees, Dede N. Ekoue, Ganesh V. Raj, A Alluri, Rajeshwar Rao Tekmal
Publikováno v:
Cancer Research. 79:P5-04
Background:We had previously reported a novel small molecule, ERX-11, that directly interacts with ER and blocks the interaction between a subset of coregulators with both native and mutant forms of ER. ERX-11 effectively blocks ER oncogenic signalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::028cb7308af60b34524e667177d1a9a4
https://doi.org/10.1158/1538-7445.sabcs18-p5-04-23
https://doi.org/10.1158/1538-7445.sabcs18-p5-04-23
Reactive oxygen species (ROS) largely originating in the mitochondria play essential roles in the metabolic and (epi)genetic reprogramming of cancer cell evolution towards more aggressive phenotypes. Recent studies have indicated that the activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cede716a09ba5ee8bd2032882e36520
https://europepmc.org/articles/PMC5689482/
https://europepmc.org/articles/PMC5689482/
