Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Dede N Ekoue"'
Autor:
Dede N. Ekoue, Emmanuel Ansong, Lenny K. Hong, Larisa Nonn, Virgilia Macias, Ryan Deaton, Rawan Rupnow, Peter H. Gann, Andre Kajdacsy-Balla, Alan M. Diamond
Publikováno v:
Antioxidants, Vol 7, Iss 11, p 167 (2018)
Glutathione peroxidase 1 (GPX1) is an extensively studied selenium-dependent protein that reduces hydrogen and lipid peroxides to water. Because of its antioxidant function and its responsiveness to dietary intakes of selenium, an essential trace ele
Externí odkaz:
https://doaj.org/article/157f0adb54874bc1ac45702ed7923b4e
Autor:
Emmanuel Ansong, Qi Ying, Dede N Ekoue, Ryan Deaton, Andrew R Hall, Andre Kajdacsy-Balla, Wancai Yang, Peter H Gann, Alan M Diamond
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127295 (2015)
Selenium-Binding Protein 1 (SBP1, SELENBP1, hSP56) is a selenium-associated protein shown to be at lower levels in tumors, and its lower levels are frequently predictive of a poor clinical outcome. Distinguishing indolent from aggressive prostate can
Externí odkaz:
https://doaj.org/article/491d50acecea4c8b977a7c7e5b910602
Autor:
RK Vadlamudi, GR Sareddy, Ganesh V. Raj, Mei Kuen Li, Rajeshwar Rao Tekmal, S Ma, J-M Ahn, Mei Zhou, T-K Lee, EM Blatt, Xihui Liu, Suryavathi Viswanadhapalli, Dede N. Ekoue
Publikováno v:
Cancer Research. 79:P4-07
Background: Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer and represents a disproportional share of the breast cancer mortality, primarily due to a lack of targeted therapies. There is a major unmet need for rationall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::395a3d99a270187bbc362b69c972629e
https://doi.org/10.1158/1538-7445.sabcs18-p4-07-01
https://doi.org/10.1158/1538-7445.sabcs18-p4-07-01
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93472 (2014)
Glutathione peroxidase activity was previously determined to be elevated in lymphocytes obtained from patients treated with the Bcr-Abl kinase inhibitor imatinib mesylate. In order to expand upon this observation, the established chronic myelogenous
Externí odkaz:
https://doaj.org/article/9519fcc58f42467885e27e1ce7ec5b93
Autor:
Larisa Nonn, Lenny Hong, Virgilia Macias, Alan M Diamond, Dede N. Ekoue, Emmanuel Ansong, Andre Kajdacsy-Balla, Peter H. Gann, Ryan Deaton, Rawan Allozi Rupnow
Publikováno v:
Antioxidants, Vol 7, Iss 11, p 167 (2018)
Antioxidants
Volume 7
Issue 11
Antioxidants
Volume 7
Issue 11
Glutathione peroxidase 1 (GPX1) is an extensively studied selenium-dependent protein that reduces hydrogen and lipid peroxides to water. Because of its antioxidant function and its responsiveness to dietary intakes of selenium, an essential trace ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0617eb06dff4940963c8673a7a308a7
https://www.mdpi.com/2076-3921/7/11/167
https://www.mdpi.com/2076-3921/7/11/167
Autor:
Dede N. Ekoue, Alan M Diamond, Li Liu, Vincent L. Freeman, Giovanna Bermano, Janaina L. S. Donadio
Publikováno v:
The Prostate. 79(5)
Background: NKX3.1 is a tumor suppressor frequently lost in prostate cancer. Previous studies by others indicated that the risks associated with reduced NKX3.1 levels can be enhanced by anti-oxidant supplementation. Selenium is an essential component
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9892205c2dbe50853bdb4780cc8b81
https://pubmed.ncbi.nlm.nih.gov/30582190
https://pubmed.ncbi.nlm.nih.gov/30582190
Publikováno v:
Cancer letters. 438
The current therapeutic armamentarium for castration-resistant prostate cancer (CRPC) includes second-generation agents such as the Androgen Receptor (AR) inhibitor enzalutamide and the androgen synthesis inhibitor abiraterone acetate, immunotherapie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd8eaaaf77372284b1db1e5d04a3ce28
https://pubmed.ncbi.nlm.nih.gov/30217566
https://pubmed.ncbi.nlm.nih.gov/30217566
Publikováno v:
Expert review of clinical pharmacology. 11(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a73002510d03e285a3255cc52f84c621
https://pubmed.ncbi.nlm.nih.gov/29439601
https://pubmed.ncbi.nlm.nih.gov/29439601
Autor:
Alan M. Diamond, Virgilia Macias, Ryan Deaton, Li Liu, Larisa Nonn, Vincent L. Freeman, Matthew J. Picklo, Gail S. Prins, Craig Lacher, Andre Kajdacsy-Balla, Peter H. Gann, Emmanuel Ansong, Dede N. Ekoue
Publikováno v:
The Prostate
Background Selenium status is inversely associated with the incidence of prostate cancer. However, supplementation trials have not indicated a benefit of selenium supplementation in reducing cancer risk. Polymorphisms in the gene encoding selenoprote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79f1b9df255c729840450f86946291c1
https://pubmed.ncbi.nlm.nih.gov/29314169
https://pubmed.ncbi.nlm.nih.gov/29314169
Autor:
GR Sareddy, Yiliao Luo, Suryavathi Viswanadhapalli, SE Weintraub, J-M Ahn, S Ma, Carlos L. Arteaga, RK Vadlamudi, Xihui Liu, Prasanna G. Alluri, T-K Lee, Kara Kassees, Dede N. Ekoue, Ganesh V. Raj, A Alluri, Rajeshwar Rao Tekmal
Publikováno v:
Cancer Research. 79:P5-04
Background:We had previously reported a novel small molecule, ERX-11, that directly interacts with ER and blocks the interaction between a subset of coregulators with both native and mutant forms of ER. ERX-11 effectively blocks ER oncogenic signalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::028cb7308af60b34524e667177d1a9a4
https://doi.org/10.1158/1538-7445.sabcs18-p5-04-23
https://doi.org/10.1158/1538-7445.sabcs18-p5-04-23