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pro vyhledávání: '"Dede Lori"'
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 753-762 (2015)
Myostatin is a TGFβ family ligand that reduces muscle mass. In cancer cells, TGFβ signalling is increased by the protein FHL1. Consequently, FHL1 may promote signalling by myostatin. We therefore tested the ability of FHL1 to regulate myostatin fun
Externí odkaz:
https://doaj.org/article/d37c35f8b7394d23b5a3600e802ebdb4
Publikováno v:
FEBS Open Bio
FEBS Open Bio, Vol 5, Iss 1, Pp 753-762 (2015)
FEBS Open Bio, Vol 5, Iss 1, Pp 753-762 (2015)
Highlights • Myostatin signals via SMADs to promote muscle wasting. • FHL1 normally promotes hypertrophy but can activate SMAD signalling. • FHL1 promoted myostatin signalling in vitro. • FHL1 promoted hypertrophy in the absence of myostatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639a14b9d754e22f0d232521045c0733