Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Decui Shao"'
Autor:
Lisha Ma, Ruiqin Shen, Jie Jiao, Xiadong Lin, Bin Zhai, Aiping Xu, Hao Luo, Limin Lu, Decui Shao
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108463- (2023)
Summary: Renal tubular epithelial cells injury is one of the most important pathological features in hyperuricemic nephropathy (HN). However, the involvement of gasdermin D (GSDMD)-mediated pyroptosis in HN remains obscure. We found GSDMD was upregul
Externí odkaz:
https://doaj.org/article/1d94240acd384b7f801440e9d1053590
Publikováno v:
Renal Failure, Vol 44, Iss 1, Pp 1780-1790 (2022)
Purpose Glomerular mesangial cell (GMC) dysfunction plays a vital role in the pathogenesis of diabetic kidney disease (DKD). Transient receptor potential canonical 6 (TRPC6) has been demonstrated to be involved in the development of DKD. However, the
Externí odkaz:
https://doaj.org/article/5790725f73cd47ecb83637346b489078
Autor:
Decui Shao, Jia Liu, Jun Ni, Zhen Wang, Yang Shen, Li Zhou, Yu Huang, Jun Wang, Hong Xue, Wei Zhang, Limin Lu
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56124 (2013)
Recent evidences suggest that endoplasmic reticulum (ER) stress was involved in multi pathological conditions, including diabetic nephropathy (DN). X-box binding protein 1(XBP1), as a key mediator of ER stress, has been proved having the capability o
Externí odkaz:
https://doaj.org/article/892d85541cd8457e8b69aa846063b698
Autor:
Hong Xue, Ping Yuan, Jun Ni, Chen Li, Decui Shao, Jia Liu, Yang Shen, Zhen Wang, Li Zhou, Wei Zhang, Yu Huang, Chen Yu, Rui Wang, Limin Lu
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74366 (2013)
Decrease in endogenous hydrogen sulfide (H2S) was reported to participate in the pathogenesis of diabetic nephropathy (DN). This study is aimed at exploring the relationship between the abnormalities in H2S metabolism, hyperglycemia-induced oxidative
Externí odkaz:
https://doaj.org/article/6fe2d37d566c4eecbdc1307bdd192d1b
Autor:
Xinxin Gan, Li Zhou, Jin-lan Xu, Naijun Miao, Yang Shen, Jun Ni, Limin Lu, Dan Xu, Decui Shao, Wei Zhang
SND p102 was first described as a transcriptional co-activator, and subsequently determined to be a co-regulator of Pim-1, STAT6 and STAT5. We previously reported that SND p102 expression was increased in high glucose-treated mesangial cells (MCs) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbb7778e7dac7ac759ad752fee5e712e
https://europepmc.org/articles/PMC6289350/
https://europepmc.org/articles/PMC6289350/
Publikováno v:
Oncology reports. 40(1)
N-(4-hydroxyphenyl)retinamide (4-HPR or fenretinide), which is a synthetic analog of all‑trans retinoic acid (ATRA), effectively inhibits the growth of several types of tumor cells; however, its molecular mechanism remains unclear. We found that 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc77e5f2b84b6eb46ee10cf4e242ffd9
https://pubmed.ncbi.nlm.nih.gov/29767236
https://pubmed.ncbi.nlm.nih.gov/29767236
Autor:
Ya-li Kong, Decui Shao, Jun Ni, Limin Lu, Xiaoxia Wang, Wei Zhang, Li Zhou, Hong Xue, Naijun Miao, Yang Shen, Jin-lan Xu
Publikováno v:
Acta pharmacologica Sinica. 37(2)
Diabetic nephropathy is one of the major complications of diabetes and the major cause of end-stage renal disease. In this study we investigated the insulin deficiency (ID) induced changes in renal mesangial cells (MCs) and in the kidney of STZ-induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfef9b517da15643b64bdbf93c9f5982
https://pubmed.ncbi.nlm.nih.gov/26775660
https://pubmed.ncbi.nlm.nih.gov/26775660
Publikováno v:
European journal of pharmacology. 758
High glucose (HG)-induced apoptosis in mesangial cells (MCs) is a critical determinant during the pathogenesis of diabetic nephropathy. The signaling cascade inducing MCs apoptosis by HG involves overproduction of reactive oxygen species. Our previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e8973a8c87c4340ab87f31ceaa1cbc6
https://pubmed.ncbi.nlm.nih.gov/25857226
https://pubmed.ncbi.nlm.nih.gov/25857226
Autor:
Limin Lu, Chen Yu, Decui Shao, Wei Zhang, Lan-jun Fu, Hong Xue, Jun Ni, Ya-li Kong, Li Zhou, Zhen Wang, Yu Huang, Yang Shen, Jia Liu
To explore the relationship between the signal transducer and activator of transcription 3 (STAT3) signaling and renal fibrosis. Rat renal tubular epithelial NRK-52E cells were treated with angiotesin II (Ang II), nicotinamide (an inhibitor of NAD+-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b7915110013eb2bcc8b950860947a1
https://europepmc.org/articles/PMC4125712/
https://europepmc.org/articles/PMC4125712/