Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Declan T, Chard"'
Autor:
Christopher E. McMurran, Trisha Mukherjee, J William L. Brown, Andrew W. Michell, Declan T. Chard, Robin J. M. Franklin, Alasdair J. Coles, Nick G. Cunniffe
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 7, Pp 1090-1094 (2022)
Abstract Remyelination efficiency declines with advancing age in animal models, but this has been harder to demonstrate in people with multiple sclerosis. We show that bexarotene, a putatively remyelinating retinoid‐X receptor agonist, shortened th
Externí odkaz:
https://doaj.org/article/6d0c103b90e94d1d9986fb871abf220e
Autor:
Carmen Tur, Francesco Grussu, Floriana De Angelis, Ferran Prados, Baris Kanber, Alberto Calvi, Arman Eshaghi, Thalis Charalambous, Rosa Cortese, Declan T. Chard, Jeremy Chataway, Alan J. Thompson, Olga Ciccarelli, Claudia A.M. Gandini Wheeler-Kingshott
Publikováno v:
NeuroImage: Clinical, Vol 33, Iss , Pp 102904- (2022)
Predicting disability in progressive multiple sclerosis (MS) is extremely challenging. Although there is some evidence that the spatial distribution of white matter (WM) lesions may play a role in disability accumulation, the lack of well-established
Externí odkaz:
https://doaj.org/article/5abc73116a16428c98d0aa21a04bb79e
Autor:
Viktor Wottschel, Declan T. Chard, Christian Enzinger, Massimo Filippi, Jette L. Frederiksen, Claudio Gasperini, Antonio Giorgio, Maria A. Rocca, Alex Rovira, Nicola De Stefano, Mar Tintoré, Daniel C. Alexander, Frederik Barkhof, Olga Ciccarelli
Publikováno v:
NeuroImage: Clinical, Vol 24, Iss , Pp - (2019)
Machine learning classification is an attractive approach to automatically differentiate patients from healthy subjects, and to predict future disease outcomes. A clinically isolated syndrome (CIS) is often the first presentation of multiple sclerosi
Externí odkaz:
https://doaj.org/article/05ece51b95f542a3a1b6aa71bbeee351
Autor:
Piet M. Bouman, Samantha Noteboom, Fernando A. Nobrega Santos, Erin S. Beck, Gregory Bliault, Marco Castellaro, Massimiliano Calabrese, Declan T. Chard, Paul Eichinger, Massimo Filippi, Matilde Inglese, Caterina Lapucci, Andrzej Marciniak, Bastiaan Moraal, Alfredo Morales Pinzon, Mark Mühlau, Paolo Preziosa, Daniel S. Reich, Maria A. Rocca, Menno M. Schoonheim, Jos W. R. Twisk, Benedict Wiestler, Laura E. Jonkman, Charles R. G. Guttmann, Jeroen J. G. Geurts, Martijn D. Steenwijk
Publikováno v:
Bouman, P M, Noteboom, S, Nobrega Santos, F A, Beck, E S, Bliault, G, Castellaro, M, Calabrese, M, Chard, D T, Eichinger, P, Filippi, M, Inglese, M, Lapucci, C, Marciniak, A, Moraal, B, Pinzon, A M, Mühlau, M, Preziosa, P, Reich, D S, Rocca, M A, Schoonheim, M M, Twisk, J W R, Wiestler, B, Jonkman, L E, Guttmann, C R G, Geurts, J J G & Steenwijk, M D 2023, ' Multicenter Evaluation of AI-generated DIR and PSIR for Cortical and Juxtacortical Multiple Sclerosis Lesion Detection ', Radiology, vol. 307, no. 2, e221425 . https://doi.org/10.1148/radiol.221425
Radiology, 307(2):e221425. Radiological Society of North America Inc.
Radiology, 307(2):e221425. Radiological Society of North America Inc.
Background: Cortical multiple sclerosis lesions are clinically relevant but inconspicuous at conventional clinical MRI. Double inversion recovery (DIR) and phase-sensitive inversion recovery (PSIR) are more sensitive but often unavailable. In the pas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5643a498d6779ddaf49e5d45e944d66
https://research.vumc.nl/en/publications/7a83468a-18ea-4243-857b-0c2b6f4e7e31
https://research.vumc.nl/en/publications/7a83468a-18ea-4243-857b-0c2b6f4e7e31
Autor:
Olga Ciccarelli, Giselle Birch, Declan T. Chard, Stephanie Mangesius, Ferran Prados, Carmen Tur, Frederik Barkhof, Lukas Haider, Arman Eshaghi, Karen Chung
Publikováno v:
Haider, L, Chung, K, Birch, G, Eshaghi, A, Mangesius, S, Prados, F, Tur, C, Ciccarelli, O, Barkhof, F & Chard, D 2021, ' Linear brain atrophy measures in multiple sclerosis and clinically isolated syndromes: A 30-year follow-up ', Journal of Neurology, Neurosurgery and Psychiatry, vol. 92, no. 8, pp. 839-846 . https://doi.org/10.1136/jnnp-2020-325421
Journal of Neurology, Neurosurgery and Psychiatry, 92(8), 839-846. BMJ Publishing Group
Journal of Neurology, Neurosurgery and Psychiatry, 92(8), 839-846. BMJ Publishing Group
ObjectiveTo determine 30-year brain atrophy rates following clinically isolated syndromes and the relationship of atrophy in the first 5 years and clinical outcomes 25 years later.MethodsA cohort of 132 people who presented with a clinically isolated
Autor:
Lukas Haider, Marios C. Yiannakas, Claudia A. M. Wheeler-Kingshott, Frederik Barkhof, Carole H. Sudre, Declan T. Chard, Baris Kanber, Alan J. Thompson, Olga Ciccarelli, Karen Chung, Rebecca S. Samson, Stephanie Mangesius, Ferran Prados, Olivia Goodkin
Publikováno v:
Brain, 144(5), 1384-1395. Oxford University Press
Brain
Haider, L, Prados, F, Chung, K, Goodkin, O, Kanber, B, Sudre, C, Yiannakas, M, Samson, R S, Mangesius, S, Thompson, A J, Gandini Wheeler-Kingshott, C A M, Ciccarelli, O, Chard, D T & Barkhof, F 2021, ' Cortical involvement determines impairment 30 years after a clinically isolated syndrome ', Brain, vol. 144, no. 5, pp. 1384-1395 . https://doi.org/10.1093/brain/awab033, https://doi.org/10.1093/brain/awab033
Brain, Vol. 144, no. 5, p. 1384-1395 (2021)
Brain
Haider, L, Prados, F, Chung, K, Goodkin, O, Kanber, B, Sudre, C, Yiannakas, M, Samson, R S, Mangesius, S, Thompson, A J, Gandini Wheeler-Kingshott, C A M, Ciccarelli, O, Chard, D T & Barkhof, F 2021, ' Cortical involvement determines impairment 30 years after a clinically isolated syndrome ', Brain, vol. 144, no. 5, pp. 1384-1395 . https://doi.org/10.1093/brain/awab033, https://doi.org/10.1093/brain/awab033
Brain, Vol. 144, no. 5, p. 1384-1395 (2021)
Many studies report an overlap of MRI and clinical findings between patients with relapsing-remitting multiple sclerosis (RRMS) and secondary progressive multiple sclerosis (SPMS), which in part is reflective of inclusion of subjects with variable di
Autor:
Iris Dekker, K. A. Meijer, Scott C Kolbe, Myrte Strik, Menno M. Schoonheim, M Pardini, Anand J. C. Eijlers, Declan T. Chard, Jeroen J. G. Geurts, Bernard M. J. Uitdehaag
Publikováno v:
Multiple Sclerosis Journal, 27(9), 1364-1373. SAGE Publications Ltd
Strik, M, Chard, D T, Dekker, I, Meijer, K A, Eijlers, A J C, Pardini, M, Uitdehaag, B M J, Kolbe, S C, Geurts, J J G & Schoonheim, M M 2021, ' Increased functional sensorimotor network efficiency relates to disability in multiple sclerosis ', Multiple Sclerosis Journal, vol. 27, no. 9, pp. 1364-1373 . https://doi.org/10.1177/1352458520966292
Multiple Sclerosis (Houndmills, Basingstoke, England)
Strik, M, Chard, D T, Dekker, I, Meijer, K A, Eijlers, A J C, Pardini, M, Uitdehaag, B M J, Kolbe, S C, Geurts, J J G & Schoonheim, M M 2021, ' Increased functional sensorimotor network efficiency relates to disability in multiple sclerosis ', Multiple Sclerosis Journal, vol. 27, no. 9, pp. 1364-1373 . https://doi.org/10.1177/1352458520966292
Multiple Sclerosis (Houndmills, Basingstoke, England)
Background: Network abnormalities could help explain physical disability in multiple sclerosis (MS), which remains poorly understood. Objective: This study investigates functional network efficiency changes in the sensorimotor system. Methods: We inc
Publikováno v:
Calvi, A, Haider, L, Prados, F, Tur, C, Chard, D & Barkhof, F 2020, ' In vivo imaging of chronic active lesions in multiple sclerosis ', Multiple Sclerosis Journal . https://doi.org/10.1177/1352458520958589
New clinical activity in multiple sclerosis (MS) is often accompanied by acute inflammation which subsides. However, there is growing evidence that a substantial proportion of lesions remain active well beyond the acute phase. Chronic active lesions
Autor:
Declan T. Chard, Ferran Prados Carrasco, Arman Eshaghi, M Pardini, Azmain Chowdhury, James William L. Brown, Claudia Gandini Wheeler-Kingshott, Baris Kanber, Rebecca S. Samson, Steven H. P. van de Pavert, Carole H. Sudre
Publikováno v:
Brown, J W L, Chowdhury, A, Kanber, B, Prados Carrasco, F, Eshaghi, A, Sudre, C H, Pardini, M, Samson, R S, van de Pavert, S H, Wheeler-Kingshott, C G & Chard, D T 2019, ' Magnetisation transfer ratio abnormalities in primary and secondary progressive multiple sclerosis ', Multiple sclerosis (Houndmills, Basingstoke, England) . https://doi.org/10.1177/1352458519841810
O2, repositorio institucional de la UOC
Universitat Oberta de Catalunya (UOC)
O2, repositorio institucional de la UOC
Universitat Oberta de Catalunya (UOC)
Background: In relapse-onset multiple sclerosis (MS), tissue abnormality – as assessed with magnetisation transfer ratio (MTR) imaging – is greater in the outer cortical and inner periventricular layers. The cause of this remains unknown but meni
Autor:
Charles R.G. Guttmann, Douglas L. Arnold, Frederik Barkhof, Daniel C. Alexander, Alan J. Thompson, Sridar Narayanan, Alexandra L. Young, Ferran Prados, Arman Eshaghi, Declan T. Chard, Peter A. Wijeratne, Olga Ciccarelli
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-3 (2021)
The original version of this Article contained an error in Fig. 2, in which the plot shown in panel c was inadvertently duplicated in panel d. The correct version of Fig. 2 is: (Figure presented.) which replaces the previous incorrect version: (Figur