Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Declan G, Gilheany"'
Autor:
Declan G. Gilheany, Saranna E Kavanagh
Publikováno v:
Organic Letters. 22:8198-8203
A series of N-substituted cyclohexyldiaminophenolic ligands for the asymmetric Grignard synthesis of tertiary alcohols is reported. The 2,5-dimethylpyrrole-decorated ligand led to improved enantioselectivities and broadened the scope of the methodolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af168c0e7e4c9c59f726027796656e1
https://doi.org/10.1021/acs.orglett.0c02629
https://doi.org/10.1021/acs.orglett.0c02629
Autor:
Claudio Monasterolo, Ryan O'Gara, Saranna E. Kavanagh, Sadbh E. Byrne, Bartosz Bieszczad, Orla Murray, Michael Wiesinger, Rebecca A. Lynch, Kirill Nikitin, Declan G. Gilheany
Publikováno v:
Chemical science. 13(21)
A new class of biaryl chiral ligands derived from 1,2-diaminocyclohexane (1,2-DACH) has been designed to enable the asymmetric addition of aliphatic and, for the first time, aromatic Grignard reagents to ketones for the preparation of highly enantioe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17d56c1f3fbe2cf6b2b9df72fe514084
https://pubmed.ncbi.nlm.nih.gov/35733895
https://pubmed.ncbi.nlm.nih.gov/35733895
Publikováno v:
ARKIVOC, Vol 2005, Iss 1, Pp 30-38 (2004)
Externí odkaz:
https://doaj.org/article/973584b2264d4427b4f38850c6bc0cab
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 194:339-342
We propose a new, potentially widely-applicable, Umpolung approach for the synthesis of quaternary phosphonium salts R3PR1 X (X = Cl, Br) from phosphine oxides R3PO. The new organic group R1 is int...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a31036217f32f936ee7c3c304756975d
https://doi.org/10.1080/10426507.2018.1541242
https://doi.org/10.1080/10426507.2018.1541242
Publikováno v:
Chemical Science. 10:6531-6538
Phenones with elongated chains are shown to be excellent substrates for ligand-promoted asymmetric Grignard synthesis of tertiary alcohols. In turn this enables the simple, short and highly enantioselective (up to 96% ee) preparation of chiral 2,2-di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55fa4676fad4d89526c1f3c3aa489996
https://doi.org/10.1039/c9sc00978g
https://doi.org/10.1039/c9sc00978g
Publikováno v:
Organic letters. 23(4)
Despite common perception, the use of strong bases in Wittig chemistry is utterly unnecessary: we report a series of novel ion-pair phosphonium carboxylate reagents which are essentially "storable ylides". These reagents are straightforwardly prepare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::617305284c8416e8665b99694f6a5462
https://pubmed.ncbi.nlm.nih.gov/33529039
https://pubmed.ncbi.nlm.nih.gov/33529039
Publikováno v:
Inorganics, Vol 4, Iss 4, p 36 (2016)
The potential energy surface for internal rotation about the phosphorus–phosphorus bond was calculated at the PCMDCM/B3LYP/6-311++G(d,p) computational level for a set of eight symmetrical, unsymmetrical and P-stereogenic diphosphines; H4P2, Me4P2,
Externí odkaz:
https://doaj.org/article/e0aab63fe3bd456eabb83a76a018da7e
Publikováno v:
European Journal of Organic Chemistry. 2018:5260-5267
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d89167aca7fc3cde85a5bb810afac02c
https://doi.org/10.1002/ejoc.201800938
https://doi.org/10.1002/ejoc.201800938
Autor:
Kirill Nikitin, Declan G. Gilheany, Elizabeth V. Jennings, Sulaiman Al Sulaimi, Yannick Ortin
Publikováno v:
Angewandte Chemie International Edition. 57:1480-1484
The complex fluxional interconversions between, otherwise very similar, phosphonium bromides and chlorides R3PX+X- (R = Alk, Ar, X = Cl or Br) was studied by NMR techniques. Their energy barriers are typically ca. 11 kcal/mol but rise rapidly as bulk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35600d12033645f9db5e1cb60678e90d
https://doi.org/10.1002/anie.201708649
https://doi.org/10.1002/anie.201708649
Publikováno v:
Chemistry - A European Journal. 23:4794-4802
P-Alkoxyphosphonium (AP) chlorides were generated by reacting P-chlorophosphonium chlorides with alcohols. Their well-known spontaneous Arbuzov-type collapse leading to phosphine oxides was studied and its rate found to be dependent on a number of fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::435226ef4ed77849f3d9e5a5a382d1a4
https://doi.org/10.1002/chem.201604898
https://doi.org/10.1002/chem.201604898