The Intestinal Efflux Transporter Inhibition Activity of Xanthones from Mangosteen Pericarp: An In Silico, In Vitro and Ex Vivo Approach

Autor: Panudda Dechwongya, Songpol Limpisood, Nawong Boonnak, Supachoke Mangmool, Mariko Takeda-Morishita, Thitianan Kulsirirat, Pattarawit Rukthong, Korbtham Sathirakul

Publikováno v: Molecules, Vol 25, Iss 24, p 5877 (2020)

The capacity of α-mangostin (α-MG) and β-mangostin (β-MG) from mangosteen pericarp on P-glycoprotein (Pgp) in silico, in vitro, and ex vivo was investigated in this study. Screening with the ADMET Predictor™ program predicted the two compounds

Externí odkaz: https://doaj.org/article/d8345b29b4834820ac89dde5712bf10a

The Potential of Non-Ionic Surfactant Against P-Glycoprotein Efflux Transporters for Drug Development System

Autor: Kulsirirat T, Rukthong P, Dechwongya P, Sathirakul K

Publikováno v: Journal of Bioequivalence & Bioavailability.

Polysorbates (Tweens) are widely used in pharmaceutical formulations as excipients, such as stabilizer or solubilizer, for poorly soluble drugs. The efflux transporters ABCB1 (P-glycoprotein, P-gp) play an essential role in limiting the oral bioavail

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::74cd270c2afe85ffad3e524fc393b9a3
https://doi.org/10.4172/jbb.1000357

The Potential of Non-Ionic Surfactant Against P-Glycoprotein Efflux Transporters for Drug Development System.

Autor: Kulsirirat, T., Rukthong, P., Dechwongya, P., Sathirakul, K.

Publikováno v: Resource: Engineering & Technology for a Sustainable World; Jan/Feb2018, Vol. 25 Issue 1, p528-529, 2p

Evaluation of the Intestinal Permeability of Rosmarinic Acid from Thunbergia laurifolia Leaf Water Extract in a Caco-2 Cell Model.

Autor: Woottisin, Nanthakarn¹ (AUTHOR) nanthakarn729@gmail.com, Sukprasert, Sophida² (AUTHOR) sophida@tu.ac.th, Kulsirirat, Thitianan³ (AUTHOR) lordrx16@gmail.com, Tharavanij, Thipaporn^4,5 (AUTHOR) thipaporn_t@yahoo.com, Sathirakul, Korbtham³ (AUTHOR) sophida@tu.ac.th

Publikováno v: Molecules. Jun2022, Vol. 27 Issue 12, p3884-N.PAG. 16p.

Antiangiogenic potential of phytochemicals from Clerodendrum inerme (L.) Gaertn investigated through in silico and quantum computational methods.

Autor: Yasmeen N; Amity Institute of Biotechnology, Amity University Rajasthan, Jaipur, Rajasthan, India., Chaudhary AA; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia., Khan S; Department of Biochemistry, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia., Ayyar PV; School of Life Science, Punyashlok Ahilyadevi Holkar Solapur University, Solapur, Maharashtra, India., Lakhawat SS; Amity Institute of Biotechnology, Amity University Rajasthan, Jaipur, Rajasthan, India., Sharma PK; Amity Institute of Biotechnology, Amity University Rajasthan, Jaipur, Rajasthan, India., Kumar V; Amity Institute of Pharmacy, Amity University Rajasthan, Jaipur, Rajasthan, India. vkumar3@jpr.amity.edu.

Publikováno v: Molecular diversity [Mol Divers] 2024 Apr 28. Date of Electronic Publication: 2024 Apr 28.