Zobrazeno 1 - 10
of 1 284
pro vyhledávání: '"Decarboxylase inhibitor"'
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Background Inhibitors of ornithine decarboxylase (ODC) are effective at preventing colorectal cancer (CRC). However, their high toxicity limits their clinical application. This study was aimed to explore the potential of microRNAs (miRNAs) a
Externí odkaz:
https://doaj.org/article/5c8b265355894efcaa3789fd9d0296d0
Publikováno v:
Cancer Medicine, Vol 10, Iss 18, Pp 6442-6455 (2021)
Abstract Rhabdomyosarcoma exhibits tumor‐specific energy metabolic changes that include the Warburg effect. Since targeting cancer metabolism is a promising therapeutic approach, we examined the antitumor effects of suppressing lipid metabolism in
Externí odkaz:
https://doaj.org/article/8b8f8098664e4aeaa0b7aa4f2c72213c
Autor:
Mohamed A. Morsy, Snehal S. Patel, Anita Bakrania, Mahmoud Kandeel, Anroop B. Nair, Jigar N. Shah, Sabah H. Akrawi, Mahmoud El-Daly
Publikováno v:
Life, Vol 12, Iss 6, p 820 (2022)
Allergic rhinitis (AR) affects 20–50% of the global population. Available treatments are limited by their adverse effects. We investigated the anti-allergic effects of catechin alone and combined with cetirizine against ovalbumin-induced AR. Rats w
Externí odkaz:
https://doaj.org/article/ba79880f7d2141e8bb4b81eb67d7d2f4
Autor:
Ilona Csoti, Natalia Koleva-Alazeh
Publikováno v:
Clinical Parkinsonism & Related Disorders, Vol 4, Iss , Pp 100087- (2021)
Background: Although diarrhea has been reported as a side effect of L-3,4- dihydroxyphenylalanine (L-DOPA)/benserazide, it is largely unknown and unrecognized, presumably because it is very rare. There is almost no literature on benserazide-induced d
Externí odkaz:
https://doaj.org/article/02694935fbcc4dce8476371be0ce4b37
Autor:
Contin, Manuela, Lopane, Giovanna, Belotti, Laura M B, Galletti, Margherita, Cortelli, Pietro, Calandra-Buonaura, Giovanna
Publikováno v:
Journal of Parkinson's Disease. 12:2519-2530
Background: Different studies, mostly with limited cohorts, have suggested the effects of patients’ characteristics on levodopa (LD) pharmacokinetics. Objective: We primarily aimed at investigating in a large population the relationship between pat
Publikováno v:
Therapeutics and Clinical Risk Management, Vol Volume 14, Pp 709-719 (2018)
Zhan-Miao Yi,1–3 Ting-Ting Qiu,1,4 Yuan Zhang,5 Na Liu,6 Suo-Di Zhai1,3 1Department of Pharmacy, Peking University Third Hospital, 2Department of Pharmacy Administration and Clinical Pharmacy, Peking University School of Pharmaceutical Science, 3In
Externí odkaz:
https://doaj.org/article/2d3b69e18fd14e968c211717a2a7b186
Autor:
S. M. Omarova, N. V. Fedorova
Publikováno v:
Klinicist, Vol 11, Iss 1, Pp 81-85 (2017)
The objective is to describe a clinical case of dopamine dysregulation syndrome (DDS) with compulsive intake of large doses of levodopa in a patient with Parkinson’s disease (PD).Materials and methods. Male patient R., born in 1956, has had PD sinc
Externí odkaz:
https://doaj.org/article/edf54a1436c9493988445f2a6a253090
Autor:
Matthew Martin, Katrin Beyer, Juan Luis Pérez-Navero, Eduardo López-Laso, Matias Mora, L. González Gutierrez-Solana, J. Martínez-Ruiz, J. Hernandez-Vara, M. Llorente, Á. García Cazorla, Juan-Luis Ramos, Rafael Artuch, María José de la Torre-Aguilar, J. Serrano Cárdenas, Pablo Mir, Beatriz Quintáns, M.J. Sobrido Gómez, A. Adarmes, J.J. Ochoa Sepúlveda, M.D. Teva, C. Castaño-de la Mota, J.C. Gómez-Esteban, Joaquín A. Fernández-Ramos, E. Moreno-Medinilla
Publikováno v:
Parkinsonism & Related Disorders. 94:67-78
Introduction In 2009, we described a possible founder effect of autosomal dominant Segawa disease in Cordoba (Spain) due to mutation c.265C>T (p. Q89*) in the GCH1 gene. We present a retrospective multicentre study aimed at improving our knowledge of
Publikováno v:
Analytical and Bioanalytical Chemistry. 414:1713-1722
In this paper is reported the selective detection and quantification of levodopa in co-presence of carbidopa. The method took advantage of the spontaneous oxidation and color development of levodopa at basic pH here driven by alkaline earth cations a
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