Zobrazeno 1 - 10
of 1 205
pro vyhledávání: '"Debu Tripathy"'
Autor:
Jangsoon Lee, Kumiko Kida, Jiwon Koh, Huey Liu, Ganiraju C. Manyam, Young Jin Gi, Dileep R. Rampa, Asha S. Multani, Jing Wang, Gitanjali Jayachandran, Dae-Won Lee, James M. Reuben, Aysegul Sahin, Lei Huo, Debu Tripathy, Seock-Ah Im, Naoto T. Ueno
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)
Abstract Background Anti-HER2 therapies, including the HER2 antibody–drug conjugates (ADCs) trastuzumab emtansine (T-DM1) and trastuzumab deruxtecan (T-DXd), have led to improved survival outcomes in patients with HER2-overexpressing (HER2+) metast
Externí odkaz:
https://doaj.org/article/96dec9fe852b4c2f9909c30d5560016b
Autor:
Jennifer H. Chen, Sridevi Addanki, Dhruvajyoti Roy, Roland Bassett, Ekaterina Kalashnikova, Erik Spickard, Henry M. Kuerer, Salyna Meas, Vanessa N. Sarli, Anil Korkut, Jason B. White, Gaiane M. Rauch, Debu Tripathy, Banu K. Arun, Carlos H. Barcenas, Clinton Yam, Himanshu Sethi, Angel A. Rodriguez, Minetta C. Liu, Stacy L. Moulder, Anthony Lucci
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Triple negative breast cancer (TNBC) is an aggressive subtype with poor prognosis. We aimed to determine whether circulating tumor DNA (ctDNA) and circulating tumor cell (CTC) could predict response and long-term outcomes to neoad
Externí odkaz:
https://doaj.org/article/f34717845d704cca8a1c2809ca2e3328
Autor:
Rania M. Mohamed, Bikash Panthi, Beatriz E. Adrada, Medine Boge, Rosalind P. Candelaria, Huiqin Chen, Mary S. Guirguis, Kelly K. Hunt, Lei Huo, Ken-Pin Hwang, Anil Korkut, Jennifer K. Litton, Tanya W. Moseley, Sanaz Pashapoor, Miral M. Patel, Brandy Reed, Marion E. Scoggins, Jong Bum Son, Alastair Thompson, Debu Tripathy, Vicente Valero, Peng Wei, Jason White, Gary J. Whitman, Zhan Xu, Wei Yang, Clinton Yam, Jingfei Ma, Gaiane M. Rauch
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Triple-negative breast cancer (TNBC) is often treated with neoadjuvant systemic therapy (NAST). We investigated if radiomic models based on multiparametric Magnetic Resonance Imaging (MRI) obtained early during NAST predict pathologic comple
Externí odkaz:
https://doaj.org/article/6a9d5085faa94e07a2d7d1b1c2688f40
Autor:
Ming Zhao, Timothy P. DiPeri, Maria Gabriela Raso, Xiaofeng Zheng, Yasmeen Qamar Rizvi, Kurt W. Evans, Fei Yang, Argun Akcakanat, Marco Roberto Estecio, Debu Tripathy, Ecaterina E. Dumbrava, Senthil Damodaran, Funda Meric-Bernstam
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-14 (2023)
Abstract TROP2 antibody drug conjugates (ADCs) are under active development. We seek to determine whether we can enhance activity of TROP2 ADCs by increasing TROP2 expression. In metaplastic breast cancers (MpBC), there is limited expression of TROP2
Externí odkaz:
https://doaj.org/article/153c2e942072429c8da59c33c6ea4273
Autor:
Bikash Panthi, Rania M. Mohamed, Beatriz E. Adrada, Medine Boge, Rosalind P. Candelaria, Huiqin Chen, Kelly K. Hunt, Lei Huo, Ken-Pin Hwang, Anil Korkut, Deanna L. Lane, Huong C. Le-Petross, Jessica W. T. Leung, Jennifer K. Litton, Sanaz Pashapoor, Frances Perez, Jong Bum Son, Jia Sun, Alastair Thompson, Debu Tripathy, Vicente Valero, Peng Wei, Jason White, Zhan Xu, Wei Yang, Zijian Zhou, Clinton Yam, Gaiane M. Rauch, Jingfei Ma
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Early prediction of neoadjuvant systemic therapy (NAST) response for triple-negative breast cancer (TNBC) patients could help oncologists select individualized treatment and avoid toxic effects associated with ineffective therapy in patients unlikely
Externí odkaz:
https://doaj.org/article/ce05b7a736b747c6b99c4058b0f5d015
Autor:
Hui Chen, Qingqing Ding, Laila Khazai, Li Zhao, Senthil Damodaran, Jennifer K. Litton, Gaiane M. Rauch, Clinton Yam, Jeffrey T. Chang, Sahil Seth, Bora Lim, Alastair M. Thompson, Elizabeth A. Mittendorf, Beatriz Adrada, Kiran Virani, Jason B. White, Elizabeth Ravenberg, Xingzhi Song, Rosalind Candelaria, Banu Arun, Naoto T. Ueno, Lumarie Santiago, Sadia Saleem, Sausan Abouharb, Rashmi K. Murthy, Nuhad Ibrahim, Mark J. Routbort, Aysegul Sahin, Vicente Valero, William Fraser Symmans, Debu Tripathy, Wei-Lien Wang, Stacy Moulder, Lei Huo
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
Background: Recent advances have been made in targeting the phosphoinositide 3-kinase pathway in breast cancer. Phosphatase and tensin homolog (PTEN) is a key component of that pathway. Objective: To understand the changes in PTEN expression over the
Externí odkaz:
https://doaj.org/article/d6308ee798424003bf82ce6d0277871d
Autor:
Zijian Zhou, Beatriz E. Adrada, Rosalind P. Candelaria, Nabil A. Elshafeey, Medine Boge, Rania M. Mohamed, Sanaz Pashapoor, Jia Sun, Zhan Xu, Bikash Panthi, Jong Bum Son, Mary S. Guirguis, Miral M. Patel, Gary J. Whitman, Tanya W. Moseley, Marion E. Scoggins, Jason B. White, Jennifer K. Litton, Vicente Valero, Kelly K. Hunt, Debu Tripathy, Wei Yang, Peng Wei, Clinton Yam, Mark D. Pagel, Gaiane M. Rauch, Jingfei Ma
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer. Neoadjuvant systemic therapy (NAST) followed by surgery are currently standard of care for TNBC with 50-60% of patients achieving pathologic complete response (p
Externí odkaz:
https://doaj.org/article/9d1afc4d0a46451ea11ba6d0e3bea0a2
Autor:
Jason A. Mouabbi, Akshara Singareeka Raghavendra, Roland L. Bassett, Amy Hassan, Debu Tripathy, Rachel M. Layman
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-7 (2022)
Abstract The addition of targeted therapies (TT) to endocrine therapy (ET) has improved the outcomes of patients with HR-positive, HER2-negative metastatic breast cancer (mBC). However, it is unknown whether patients with invasive lobular carcinoma (
Externí odkaz:
https://doaj.org/article/982f3e9cb56b48ee9ecd4add8542b9a0
Autor:
Haven R. Garber, Akshara Singareeka Raghavendra, Michael Lehner, Wei Qiao, Angelica M. Gutierrez-Barrera, Debu Tripathy, Banu Arun, Nuhad K. Ibrahim
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-8 (2022)
Abstract Patients with hereditary mutations in BRCA1 or BRCA2 (gBRCA1/2) and breast cancer have distinct tumor biology, and encompass a predilection for brain metastasis (BM). We looked into baseline risk of BMs among gBRCA1/2 patients. Patients with
Externí odkaz:
https://doaj.org/article/f030913dffdd4ede9b5d864d22d62e01
Autor:
Zhan Xu, David E. Rauch, Rania M. Mohamed, Sanaz Pashapoor, Zijian Zhou, Bikash Panthi, Jong Bum Son, Ken-Pin Hwang, Benjamin C. Musall, Beatriz E. Adrada, Rosalind P. Candelaria, Jessica W. T. Leung, Huong T. C. Le-Petross, Deanna L. Lane, Frances Perez, Jason White, Alyson Clayborn, Brandy Reed, Huiqin Chen, Jia Sun, Peng Wei, Alastair Thompson, Anil Korkut, Lei Huo, Kelly K. Hunt, Jennifer K. Litton, Vicente Valero, Debu Tripathy, Wei Yang, Clinton Yam, Jingfei Ma
Publikováno v:
Cancers, Vol 15, Iss 19, p 4829 (2023)
Accurate tumor segmentation is required for quantitative image analyses, which are increasingly used for evaluation of tumors. We developed a fully automated and high-performance segmentation model of triple-negative breast cancer using a self-config
Externí odkaz:
https://doaj.org/article/13a3720095084e2faf7f2ac9d1c1eb92