Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Debra Weih"'
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42741 (2012)
BackgroundConstitutive activation of the alternative NF-κB pathway leads to marginal zone B cell expansion and disorganized spleen microarchitecture. Furthermore, uncontrolled alternative NF-κB signaling may result in the development and progressio
Externí odkaz:
https://doaj.org/article/d13c4b0f40de4791ba85cb451391c701
Autor:
Nuno R dos Santos, Maryvonne Williame, Stéphanie Gachet, Françoise Cormier, Anne Janin, Debra Weih, Falk Weih, Jacques Ghysdael
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2555 (2008)
BACKGROUND: The Rel/NF-kappaB transcription factors are often activated in solid or hematological malignancies. In most cases, NF-kappaB activation is found in malignant cells and results from activation of the canonical NF-kappaB pathway, leading to
Externí odkaz:
https://doaj.org/article/93370d6cf1e54611a04af7bff76c713b
Autor:
Marc Riemann, Elke Meier, Helga Freytag, Debra Weih, Falk Weih, Nico Andreas, Maria Fedoseeva, Ulf Klein, Ruth Schmidt-Ullrich, Zhao-Qi Wang
Publikováno v:
Journal of autoimmunity, 81:56-67
Medullary thymic epithelial cells (mTECs) contribute to self-tolerance by expressing and presenting peripheral tissue antigens for negative selection of autoreactive T cells and differentiation of natural regulatory T cells. The molecular control of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6cba8ce4e1f752a1f63569aaffaca33
http://edoc.mdc-berlin.de/16447/1/16447oa.pdf
http://edoc.mdc-berlin.de/16447/1/16447oa.pdf
Autor:
Martin Witzenrath, Branislav Krljanac, Desheng Hu, Debra Weih, Katrin Reppe, Ilse D. Jacobsen, Ievgen Koliesnik, Falk Weih
Publikováno v:
European Journal of Immunology. 44:662-672
Formation of the splenic marginal zone (MZ) depends on the alternative NF-κB signaling pathway. Recently, we reported that unrestricted activation of this pathway in NF-κB2/p100-deficient (p100(-/-) ) knock-in mice alters the phenotype of MZ stroma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41e9c9874bdaad2b2f8b967c3c529b13
https://doi.org/10.1002/eji.201343484
https://doi.org/10.1002/eji.201343484
Autor:
Marija Trajkovic-Arsic, Theo J. Visser, Claudia Groba, Julia Müller, Debra Weih, Veerle Darras, Sooyeon Lee, Heike Heuer, Karl Bauer
Publikováno v:
Endocrinology, 151(10), 5053-5062. Endocrine Society
In patients, inactivating mutations in the gene encoding the thyroid hormone-transporting monocarboxylate transporter 8 (Mct8) are associated with severe mental and neurological deficits and disturbed thyroid hormone levels. The latter phenotype char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8b181a37fa3659b2f681eefe2cafc3
https://pure.eur.nl/en/publications/6d761b48-5631-47c7-b37f-5911cbe0442b
https://pure.eur.nl/en/publications/6d761b48-5631-47c7-b37f-5911cbe0442b
Autor:
Yilang Tang, Sonja Reissig, Nadine Hövelmeyer, Debra Weih, Alexey Nikolaev, Falk Weih, Marc Riemann, Ari Waisman
Publikováno v:
Immunology and cell biology. 93(6)
The cross talk between thymocytes and the thymic epithelium is critical for T-cell development and the establishment of central tolerance. Medullary thymic epithelial cells (mTECs) are located in the thymic medulla and mediate the elimination of self
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d6ed9c8592ebf9c0e8dbb4589352cc3
https://pubmed.ncbi.nlm.nih.gov/25601276
https://pubmed.ncbi.nlm.nih.gov/25601276
Autor:
Branislav, Krljanac, Debra, Weih, Ilse D, Jacobsen, Desheng, Hu, Ievgen, Koliesnik, Katrin, Reppe, Martin, Witzenrath, Falk, Weih
Publikováno v:
European journal of immunology. 44(3)
Formation of the splenic marginal zone (MZ) depends on the alternative NF-κB signaling pathway. Recently, we reported that unrestricted activation of this pathway in NF-κB2/p100-deficient (p100(-/-) ) knock-in mice alters the phenotype of MZ stroma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::32528fbeed6607bd8e5671cb6cc1d148
https://pubmed.ncbi.nlm.nih.gov/24242887
https://pubmed.ncbi.nlm.nih.gov/24242887
Autor:
Vanessa Kuch, Diana Plaumann, Luca Quagliata, Jaya Krishnan, Melanie Rothley, Wilko Thiele, Jonathan P. Sleeman, Debra Weih, Herbert A. Weich
VEGFR-3 is a transmembrane receptor tyrosine kinase that is activated by its ligands VEGF-C and VEGF-D. Although VEGFR-3 has been linked primarily to the regulation of lymphangiogenesis, in the present study, we demonstrate a role for VEGFR-3 in mega
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c9685a0a7571ce85901d1121f3e891c
https://hdl.handle.net/10033/245952
https://hdl.handle.net/10033/245952
Autor:
Michael Kiehntopf, James C. Paton, Michael Bauer, Ulrich A. Maus, Nadine Ding, Martina Weber, Ralf A. Claus, David Enot, Abiodun D. Ogunniyi, Emeka I. Igwe, Debra Weih, Yoram Vodovotz, Hans P. Deigner, Sandro Lambeck, Lucien Frappart, David E. Briles, Matthias Kohl, Stefanie Henken, Thomas Kamradt
Community-acquired pneumonia presents a spectrum of clinical phenotypes, from lobar pneumonia to septic shock, while mechanisms underlying progression are incompletely understood. In a transcriptomic and metabolomic study across tissues, we examined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afeddcc0a0df3a92252f90e107437ef1
https://www.ncbi.nlm.nih.gov/pubmed/22415311
https://www.ncbi.nlm.nih.gov/pubmed/22415311
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 8, p e42741 (2012)
PLoS ONE, Vol 7, Iss 8, p e42741 (2012)
BackgroundConstitutive activation of the alternative NF-κB pathway leads to marginal zone B cell expansion and disorganized spleen microarchitecture. Furthermore, uncontrolled alternative NF-κB signaling may result in the development and progressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::461ab2feff283f6bf79fd307f28319cb
https://pubmed.ncbi.nlm.nih.gov/22880094
https://pubmed.ncbi.nlm.nih.gov/22880094