Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Debra U. Chung"'
Publikováno v:
Breast Cancer: Basic and Clinical Research, Vol 2011, Iss 5, Pp 175-199 (2011)
Externí odkaz:
https://doaj.org/article/1a283a2e1d2c47acbc6147b382cd481b
Autor:
William Y. Luo, Helena R. Chang, Hong Zhao, Sophia K. Apple, Jeongyoon Song, Minna Lee, Debra U. Chung, Richard J. Pietras, Xinyu Deng, Xiancheng Wu
Publikováno v:
Oncotarget
Oncotarget, vol 8, iss 24
Oncotarget, vol 8, iss 24
Breast cancer (BC) is a leading cause of cancer-related death in women. Adjuvant systemic chemotherapies are effective in reducing risks of recurrence and have contributed to reduced BC mortality. Although targeted adjuvant treatments determined by b
Autor:
John A. Glaspy, Helena R. Chang, Jeffrey Gornbein, Robert Elashoff, Debra U. Chung, Mary Ann Allison, Frederic C. Kass
Publikováno v:
Cancer. 116:4227-4237
BACKGROUND: In this study, the authors evaluated whether a pathologic complete response (pCR) or a clinical complete response (cCR) to neoadjuvant treatment in patients with locally advanced breast cancer differed among the 3 subtypes of breast cance
Autor:
Sophia K. Apple, Jeffrey Gornbein, Minh-an Cao, Minna K. Lee, Leo A. Varzi, Helena R. Chang, Debra U. Chung
Publikováno v:
BioMed Research International, Vol 2015 (2015)
BioMed Research International
BioMed Research International
Background. Studies have shown that young breast cancer patients have more advanced disease and worse survival compared to older patients. Our objective was to study disease characteristics and survival in the subset of young women with hormone recep
Proteomic-based biosignatures in breast cancer classification and prediction of therapeutic response
Autor:
Jianbo He, Debra U. Chung, Stephen A. Whelan, Helena R. Chang, Ming Lu, Dejun Shen, Kym F. Faull, Julian P. Whitelegge, Romaine E. Saxton
Publikováno v:
International Journal of Proteomics
Protein-based markers that classify tumor subtypes and predict therapeutic response would be clinically useful in guiding patient treatment. We investigated the LC-MS/MS-identified protein biosignatures in 39 baseline breast cancer specimens includin
Autor:
Jianbo He, Debra U. Chung, Romaine E. Saxton, Kym F. Faull, Helena R. Chang, Dejun Shen, Julian P. Whitelegge
Publikováno v:
International journal of oncology. 35(4)
Chemotherapy is often used for breast cancer treatment, but individual outcome varies widely. We hypothesized that tumor proteomic profiles obtained prior to chemotherapy may predict the individual tumor response to treatment. The goal of our study w
Publikováno v:
Breast Cancer : Basic and Clinical Research
Breast Cancer: Basic and Clinical Research, Vol 5 (2011)
Breast Cancer: Basic and Clinical Research, Vol 2011, Iss 5, Pp 175-199 (2011)
Breast Cancer: Basic and Clinical Research, Vol 5 (2011)
Breast Cancer: Basic and Clinical Research, Vol 2011, Iss 5, Pp 175-199 (2011)
Notorious for its poor prognosis and aggressive nature, triple-negative breast cancer (TNBC) is a heterogeneous disease entity. The nature of its biological specificity, which is similar to basal-like cancers, tumors arising in BRCA1 mutation carrier
Publikováno v:
Cancer Research. 69:1100-1100
Background: Neoadjuvant systemic treatment has become a standard choice for locally advanced breast cancer with many proposed benefits in achieving clear margins, preserving breasts, reducing relapse and improving survival. Recently, we completed a n
Publikováno v:
Journal of Clinical Oncology. 27:e11573-e11573
e11573 Background: Neoadjuvant chemotherapy (NAC) has been widely used in patients with LABC. Although survival rates after neoadjuvant and adjuvant therapy are similar, NAC was shown to increase lumpectomy surgery and allow in vivo evaluation of tre
Publikováno v:
Journal of Clinical Oncology. 26:604-604
604 Background: Breast cancer is heterogeneous with subtypes having distinct biologies and clinical outcomes. This study determined whether pCR of breast cancer to 4 cycles of neoadjuvant T/C is af...