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Autor:
Debra Steplock, F. T. Kear, Edward J. Weinman, Anna V.P. Santos, Jianfei Ma, A. A. Bernardo, R. Brooks Robey
Publikováno v:
Journal of Clinical Investigation. 104:195-201
In the renal proximal tubule, the activities of the basolateral Na+/HCO3– cotransporter (NBC) and the apical Na+/H+ exchanger (NHE3) uniformly vary in parallel, suggesting that they are coordinately regulated. PKA-mediated inhibition of NHE3 is med