Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Debra Snow"'
Autor:
Marie Blais, Douglas Ferguson, Mark Pietras, Jim Fikes, Abhishek G. Sathe, Sally A. Price, Anshul Gupta, Melanie Galvin, Michael R. Hale, Robert L. Walsky, Yvonne P. Dragan, Frank McGrath, Crystal Brown, Paul J. Ciaccio, Gunther Kern, Matthew Wagoner, Letitia Cheatham, Nakpangi Johnson, Patricia Bentley, Natalie Keirstead, Debra Snow, Wenli Luo, Jennifer C. Sasaki
Publikováno v:
Toxicological Sciences. 137:278-291
Despite six decades of clinical experience with the polymyxin class of antibiotics, their dose-limiting nephrotoxicity remains difficult to predict due to a paucity of sensitive biomarkers. Here, we evaluate the performance of standard of care and ne
Autor:
Harriet, Kamendi, Herbert, Barthlow, David, Lengel, Marie-Eve, Beaudoin, Debra, Snow, Jerome T, Mettetal, Russell A, Bialecki
Publikováno v:
British journal of pharmacology. 173(19)
While the molecular pathways of baclofen toxicity are understood, the relationships between baclofen-mediated perturbation of individual target organs and systems involved in cardiovascular regulation are not clear. Our aim was to use an integrative
Autor:
Russell Bialecki, Wenli Luo, Yvonne P. Dragan, Harriet Kamendi, Herbert Barthlow, Nilaben Patel, Patricia Bentley, Natalie Keirstead, Debra Snow, Ying Zhou, Meredith Crosby
Publikováno v:
Toxicology and applied pharmacology. 289(3)
Doxorubicin (DOX) is a potent and effective broad-spectrum anthracycline antitumor agent, but its clinical usefulness is restricted by cardiotoxicity. This study compared pharmacokinetic, functional, structural and biochemical effects of single dose