Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Debra S. Yee"'
Autor:
Pablo Canales-Herrerias, Yolanda Garcia-Carmona, Joan Shang, Hadar Meringer, Debra S. Yee, Lin Radigan, Sofija Buta, Gustavo Martinez-Delgado, Michael Tankelevich, Drew Helmus, Marla Dubinsky, Annelie Everts-van der Mind, Thierry Dervieux, Dusan Bogunovic, Jean-Frederic Colombel, Jason M. Brenchley, Jeremiah Faith, Charlotte Cunningham-Rundles, Andrea Cerutti, Saurabh Mehandru
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 12 (2023)
Externí odkaz:
https://doaj.org/article/6c4e096e26384d1ab3d1fba19786baa0
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Many proteins involved in the pathogenic mechanisms of amyotrophic lateral sclerosis (ALS) are remarkably similar to proteins that form prions in the yeast Saccharomyces cerevisiae. These ALS-associated proteins are not orthologs of yeast prion prote
Externí odkaz:
https://doaj.org/article/9ead2a83834a4f04b9816147087561ca
Autor:
Izzy Owen, Frank Shewmaker, Isabelle Hannula, Hala Wyne, Debra S. Yee, Kevin Gery, Meenakshi Sundrum, Shannon N Rhoads
Publikováno v:
Molecular Biology of the Cell
Fused in Sarcoma (FUS) is a ubiquitously expressed protein that can phase-separate from nucleoplasm and cytoplasm into distinct liquid-droplet structures. It is predominantly nuclear and most of its functions are related to RNA and DNA metabolism. Ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c76cd4238ee777ba718bd6856260c5
https://doi.org/10.1091/mbc.e20-05-0290
https://doi.org/10.1091/mbc.e20-05-0290
Autor:
Victoria Johnson, Izzy Owen, Theodora Myrto Perdikari, Hala Wyne, Nicolas L. Fawzi, Robert L. Kortum, Frank Shewmaker, Debra S. Yee, Jeremy T. Smyth
Publikováno v:
J Cell Sci
Myxoid liposarcoma is caused by a chromosomal translocation resulting in a fusion protein comprised of the N terminus of FUS (fused in sarcoma) and the full-length transcription factor CHOP (CCAAT/enhancer-binding protein homologous protein, also kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c5ce27469da3c0f6da929b4fe25f62
https://doi.org/10.1242/jcs.258578
https://doi.org/10.1242/jcs.258578
Autor:
Nicolas L. Fawzi, Izzy Owen, Debra S. Yee, Victoria Johnson, Robert L. Kortum, Theodora Myrto Perdikari, Jeremy T. Smyth, Frank Shewmaker, Hala Wyne
Myxoid liposarcoma is caused by a chromosomal translocation resulting in a fusion protein comprised of the N-terminus of FUS (fused in sarcoma) and the full-length transcription factor CHOP (CCAAT/Enhancer Binding Protein Homologous Protein). FUS fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dff635314012b29f763fdabff828c50
https://doi.org/10.1101/2021.02.24.432743
https://doi.org/10.1101/2021.02.24.432743
Autor:
Robert N. O'Meally, Cameron G. Newcombe, Debra S. Yee, Robert N. Cole, Zachary T. Monahan, Frank Shewmaker, Andrew Y. Leung, Shannon N Rhoads
Publikováno v:
Molecular Biology of the Cell
FUS (fused in sarcoma) is an abundant, predominantly nuclear protein involved in RNA processing. Under various conditions, FUS functionally associates with RNA and other macromolecules to form distinct, reversible phase-separated liquid structures. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d744e7f3271a6d1976ea18670ecae7
http://europepmc.org/articles/PMC6085830
http://europepmc.org/articles/PMC6085830
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 19, Iss 3, p 886 (2018)
International Journal of Molecular Sciences, Vol 19, Iss 3, p 886 (2018)
Subcellular mislocalization and aggregation of the human FUS protein occurs in neurons of patients with subtypes of amyotrophic lateral sclerosis and frontotemporal dementia. FUS is one of several RNA-binding proteins that can functionally self-assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::796d9d00eefd3b23c57371acf3bdd403
http://europepmc.org/articles/PMC5877747
http://europepmc.org/articles/PMC5877747