Výsledky vyhledávání - "Debra Rzewnicki"

Kinetic modeling and mathematical analysis indicate that acute phase gene expression in Hep 3B cells is regulated by both transcriptional and posttranscriptional mechanisms

Autor: Shun-Lin Jiang, Irving Kushner, Debra Rzewnicki, J. Sipe, D. Samols, S. S. Macintyre, I. Greber

Publikováno v: Journal of Clinical Investigation. 95:1253-1261

To evaluate the possible role of posttranscriptional mechanisms in the acute phase response, we determined the kinetics of transcription (by nuclear run-on assay) and mRNA accumulation of five human acute phase genes in Hep 3B cells incubated with co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190f05031e6fbd85706086c2a2101029
https://doi.org/10.1172/jci117775

Zobrazit plný text záznamu

The acute phase response: General aspects

Autor: Debra Rzewnicki, Irving Kushner

Publikováno v: Baillière's Clinical Rheumatology. 8:513-530

The acute phase response in a given individual represents the integrated sum of multiple, separately regulated changes. Although many of these changes commonly occur together in affected individuals, clinical experience indicates that not all of them

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::689dd4676fdcc713d264e3dc26b98557
https://doi.org/10.1016/s0950-3579(05)80113-x

Zobrazit plný text záznamu

Quantitative and qualitative alterations of acute-phase proteins in healthy elderly persons

Autor: Debra Rzewnicki, Sally L. Hodder, Amasa B. Ford, Stanley P. Ballou, Lorraine C. Mion, Jean D. Sipe, Gerard Lozanski, Irving Kushner

Publikováno v: Age and ageing. 25(3)

To assess acute-phase proteins in relation to ageing, we measured serum concentrations of C-reactive protein of AGP in 131 healthy elderly individuals (aged >/= 65 years) living independently in the community, and 47 healthy younger individuals. Conc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d0d3dc9bd78576fbe5bb060e27f7a58
https://pubmed.ncbi.nlm.nih.gov/8670558

Zobrazit plný text záznamu

The effect of interleukin-1 on C-reactive protein expression in Hep3B cells is exerted at the transcriptional level

Autor: Dongxiao Zhang, David Samols, Debra Rzewnicki, Irving Kushner, Shun-Lin Jiang

Publikováno v: The Biochemical journal. 310

The combination of interleukin 6 (IL-6) and interleukin 1 (IL-1) synergistically induces the human acute-phase reactant, C-reactive protein (CRP) in Hep3B cells. While previous studies have indicated that IL-6 induces transcription of CRP, the mode o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be08ca49237be4e9d5689c4c2ca1c61
https://pubmed.ncbi.nlm.nih.gov/7646436

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání