Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Debra P. Merrill"'
Autor:
Massimo Galli, Ting-Chao Chou, Simona La Seta Catamancio, Martin S. Hirsch, Elisabetta Bulgheroni, Debra P. Merrill, Otto O. Yang, Francesco Croce, Stefano Rusconi, Steven H. Herrmann, Paola Citterio
Publikováno v:
Antiviral Therapy. 5:199-204
Compounds that can block the CXCR4 chemokine receptor are a promising new class of antiretroviral agents. In these experiments we studied the effect of a modified form of the native stromal cell-derived factor-1 (SDF-1), Met-SDF-1β. The in vitro sus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1920a271fe06e4a8a7cd3020bc2da6b
https://doi.org/10.1177/135965350000500304
https://doi.org/10.1177/135965350000500304
Autor:
Bruce D. Walker, Debra P. Merrill, Martin S. Hirsch, Richard T. D'Aquila, Cécile Tremblay, Paul E. Sax, Stephen L. Boswell, Javier Martinez-Picado, Johnson T. Wong
Publikováno v:
The Journal of Infectious Diseases. 179:345-351
CD4 lymphocyte regenerative capacity was evaluated by use of an ex vivo outgrowth assay in human immunodeficiency virus (HIV)-1-infected subjects enrolled in a clinical trial (Merck 039). CD4 lymphocytes were selectively expanded in vitro by T cell r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c14219785a04e7fa93403719da70eaa
https://doi.org/10.1086/314591
https://doi.org/10.1086/314591
Publikováno v:
Antiviral Therapy. 4:29-34
Can aggressive anti-human immunodeficiency virus (HIV) induction regimens be simplified after sufficient virus suppression is achieved? In vitro studies were conducted to evaluate the hypothesis that aggressive induction regimens could be followed by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5de39a978262ab6bbafbf2660fe45bbc
https://doi.org/10.1177/135965359900400104
https://doi.org/10.1177/135965359900400104
Publikováno v:
Journal of Infectious Diseases. 173:355-364
Two- and three-drug combinations of lamivudine or stavudine with other antiretroviral drugs were evaluated for activity against human immunodeficiency virus type 1 (HIV-1) activity in peripheral blood mononuclear cells. Other agents included zidovudi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::791b5fadf2bf793fb0667ec573cbd385
https://doi.org/10.1093/infdis/173.2.355
https://doi.org/10.1093/infdis/173.2.355
Publikováno v:
Journal of Infectious Diseases. 170:1361-1366
Combination regimens against human immunodeficiency virus type 1 (HIV-1) were studied in granulocyte-macrophage colony-stimulating factor (GM-CSF)-stimulated monocyte/macrophage cultures. Regimens included those that inhibited the same target (revers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9bee0d3e7459c47e6abed7f6e63c816
https://doi.org/10.1093/infdis/170.6.1361
https://doi.org/10.1093/infdis/170.6.1361
Autor:
Richard T. D'Aquila, Debra P. Merrill, M. S. Hirsch, T. Mazzulli, Stefano Rusconi, Majaz Moonis, Ting-Chao Chou
Publikováno v:
Antimicrobial Agents and Chemotherapy. 38:656-661
We compared the in vitro efficacies of two-, three-, and four-drug combinations given continuously or in alternating regimens against a clinical isolate of human immunodeficiency virus type 1. In H9 cells and peripheral blood mononuclear cells, at th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3428c00e6ee70267a88fa5284e67ee4
https://doi.org/10.1128/aac.38.4.656
https://doi.org/10.1128/aac.38.4.656
Autor:
Richard T. D'Aquila, Yung Kang Chow, Joseph J. Eron, Joan C. Kaplan, L. J. Bechtel, Debra P. Merrill, Martin S. Hirsch
Publikováno v:
Nature. 361:650-654
Wild-type reverse transcriptase has evolved for the survival of human immunodeficiency virus type 1 (HIV-1) by natural selection. In contrast, therapy relying on inhibitors of reverse transcriptase by nucleosides like zidovudine (AZT) or dideoxyinosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08720bb296a0ade9619c6725a7ab09d3
https://doi.org/10.1038/361650a0
https://doi.org/10.1038/361650a0
Publikováno v:
Antimicrobial Agents and Chemotherapy. 36:1559-1562
The combination of zidovudine (AZT) and 2',3'-dideoxycytidine synergistically inhibits human immunodeficiency virus type 1 (HIV-1) replication in vitro with AZT-sensitive and AZT-resistant clinical isolates and HIV-1IIIB. Synergy was determined by th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6882de27ec11a2dd5e950d3ad4741c6a
https://doi.org/10.1128/aac.36.7.1559
https://doi.org/10.1128/aac.36.7.1559
Publikováno v:
Journal of Infectious Diseases. 161:1059-1067
Optimal management of human immunodeficiency virus type 1 (HIV-1) infections may require combinations of agents that attack different targets in the viral replicative cycle. Zidovudine (AZT), recombinant soluble CD4 (rsCD4), and recombinant interfero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ca45b71e3384bd25c7009c1d6982345
https://doi.org/10.1093/infdis/161.6.1059
https://doi.org/10.1093/infdis/161.6.1059
Autor:
M S Osburne, P V Pallai, Majaz Moonis, S K Singh, K J Willis, Edith A. Neidhardt, J C Jenson, A T Profy, M. S. Hirsch, Stefano Rusconi, Debra P. Merrill
Publikováno v:
Scopus-Elsevier
PIC 024-4 and PRO 2000 are naphthalene sulfonate polymers that bind to CD4 with nanomolar affinity and block binding of gp120. Both have activity against human immunodeficiency virus type 1 in H9 cells, peripheral blood mononuclear cells, and primary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64e759cf218b4c1d5936550974d2e1e
https://doi.org/10.1128/aac.40.1.234
https://doi.org/10.1128/aac.40.1.234