Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Debra M. Krupke"'
Autor:
Dale A. Begley, Debra M. Krupke, John P. Sundberg, Emily L. Jocoy, Joel E. Richardson, Steven B. Neuhauser, Carol J. Bult
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 4 (2023)
Externí odkaz:
https://doaj.org/article/b28c3576686e494f9189eab951250d02
Autor:
Zdenka Dudová, Nathalie Conte, Jeremy Mason, Dalibor Stuchlík, Radim Peša, Csaba Halmagyi, Zinaida Perova, Abayomi Mosaku, Ross Thorne, Alex Follette, Ľuboslav Pivarč, Radim Šašinka, Muhammad Usman, Steven Neuhauser, Dale A. Begley, Debra M. Krupke, Massimiliano Frassà, Alessandro Fiori, Riccardo Corsi, Luca Vezzadini, Claudio Isella, Andrea Bertotti, Carol Bult, Helen Parkinson, Enzo Medico, Terrence Meehan, Aleš Křenek
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Background Patient-derived xenografts (PDX) mice models play an important role in preclinical trials and personalized medicine. Sharing data on the models is highly valuable for numerous reasons – ethical, economical, research cross valida
Externí odkaz:
https://doaj.org/article/f99e9bc8c35f4c12ae94bc2bd9b450b1
Autor:
Zinaida Perova, Mauricio Martinez, Tushar Mandloi, Federico Lopez Gomez, Csaba Halmagyi, Alex Follette, Jeremy Mason, Steven Newhauser, Dale A Begley, Debra M Krupke, Carol Bult, Helen Parkinson, Tudor Groza
Publikováno v:
Nucleic Acids Research. 51:D1360-D1366
PDCM Finder (www.cancermodels.org) is a cancer research platform that aggregates clinical, genomic and functional data from patient-derived xenografts, organoids and cell lines. It was launched in April 2022 as a successor of the PDX Finder portal, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1439d5865963196b440a5e407f900f8c
https://doi.org/10.1093/nar/gkac1021
https://doi.org/10.1093/nar/gkac1021
Autor:
Carol J. Bult, Atul J. Butte, Helen Parkinson, Marcel Kool, Stefan M. Pfister, Frédéric Amant, S. John Weroha, Alana Welm, David M. Weinstock, Robert J. Wechsler-Reya, Emilie Vinolo, Livio Trusolino, Je Kyung Seong, Oscar M. Rueda, Daniel S. Peeper, James M. Olson, Steven B. Neuhauser, Enzo Medico, Jeremy Mason, K.C. Kent Lloyd, Michael T. Lewis, Tin O. Khor, Kristel Kemper, Jos Jonkers, Peter J. Houghton, Els Hermans, Melissa A. Haendel, Danielle Greenawalt, Neal C. Goodwin, Kristopher K. Frese, Stephane Ferretti, Yvonne A. Evrard, Olivier Duchamp, James H. Doroshow, Jonathan R. Dry, Heidi Dowst, Dominic A. Clark, Amanda L. Christie, Carlos Caldas, Annette T. Byrne, Matthew H. Brush, Alejandra Bruna, Andrea Bertotti, Debra M. Krupke, Dale A. Begley, Patrick Dunn, Jeffrey A. Wiser, Zhiping Gu, Sebastian Brabetz, Mark A. Murakami, Giorgio Inghirami, Theodore Goldstein, Nathalie Conte, Terrence F. Meehan
Patient-derived tumor xenograft (PDX) mouse models have emerged as an important oncology research platform to study tumor evolution, mechanisms of drug response and resistance, and tailoring chemotherapeutic approaches for individual patients. The la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0373627dabe0ae72d83c81ddf8478d17
https://doi.org/10.1158/0008-5472.c.6510291.v1
https://doi.org/10.1158/0008-5472.c.6510291.v1
Autor:
Carol J. Bult, Atul J. Butte, Helen Parkinson, Marcel Kool, Stefan M. Pfister, Frédéric Amant, S. John Weroha, Alana Welm, David M. Weinstock, Robert J. Wechsler-Reya, Emilie Vinolo, Livio Trusolino, Je Kyung Seong, Oscar M. Rueda, Daniel S. Peeper, James M. Olson, Steven B. Neuhauser, Enzo Medico, Jeremy Mason, K.C. Kent Lloyd, Michael T. Lewis, Tin O. Khor, Kristel Kemper, Jos Jonkers, Peter J. Houghton, Els Hermans, Melissa A. Haendel, Danielle Greenawalt, Neal C. Goodwin, Kristopher K. Frese, Stephane Ferretti, Yvonne A. Evrard, Olivier Duchamp, James H. Doroshow, Jonathan R. Dry, Heidi Dowst, Dominic A. Clark, Amanda L. Christie, Carlos Caldas, Annette T. Byrne, Matthew H. Brush, Alejandra Bruna, Andrea Bertotti, Debra M. Krupke, Dale A. Begley, Patrick Dunn, Jeffrey A. Wiser, Zhiping Gu, Sebastian Brabetz, Mark A. Murakami, Giorgio Inghirami, Theodore Goldstein, Nathalie Conte, Terrence F. Meehan
A figure showing the process of generating and using PDX models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e07c88d40f7248397f4cc8053bf7da
https://doi.org/10.1158/0008-5472.22419099
https://doi.org/10.1158/0008-5472.22419099
Autor:
Zinaida Perova, Mauricio Martinez, Tushar Mandloi, Federico Lopez Gomez, Csaba Halmagyi, Alex Follette, Jeremy Mason, Steven Neuhauser, Dale A. Begley, Debra M. Krupke, Carol Bult, Helen Parkinson, Tudor Groza, Marcelo P. Rios Almanza
Publikováno v:
Cancer Research. 83:4682-4682
PDCM Finder (www.cancermodels.org) is a cancer research platform that aggregates clinical, genomic and functional data from patient-derived xenografts, organoids and cell lines. Currently, the portal has over 6300 models across 13 cancer types, inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4848fe5c02e76243c24d5fcd7213dec5
https://doi.org/10.1158/1538-7445.am2023-4682
https://doi.org/10.1158/1538-7445.am2023-4682
Autor:
Dale A. Begley, Debra M. Krupke, Steven B. Neuhauser, Emily L. Jocoy, John P. Sundberg, Carol J. Bult
Publikováno v:
Cancer Research. 83:14-14
The laboratory mouse is the premier animal model system for in vivo studies of the genetic and genomic basis of cancer in humans. Although thousands of mouse models have been generated, finding relevant data and knowledge about these models is compli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61e3ae6bd6f42bd9bb632c216cca3142
https://doi.org/10.1158/1538-7445.am2023-14
https://doi.org/10.1158/1538-7445.am2023-14
Autor:
Zdenka Dudová, Nathalie Conte, Jeremy Mason, Dalibor Stuchlík, Radim Peša, Csaba Halmagyi, Zinaida Perova, Abayomi Mosaku, Ross Thorne, Alex Follette, Ľuboslav Pivarč, Radim Šašinka, Muhammad Usman, Steven Neuhauser, Dale A. Begley, Debra M. Krupke, Massimiliano Frassà, Alessandro Fiori, Riccardo Corsi, Luca Vezzadini, Claudio Isella, Andrea Bertotti, Carol Bult, Helen Parkinson, Enzo Medico, Terrence Meehan, Aleš Křenek
Publikováno v:
BMC genomics. 23(1)
Background Patient-derived xenografts (PDX) mice models play an important role in preclinical trials and personalized medicine. Sharing data on the models is highly valuable for numerous reasons – ethical, economical, research cross validation etc.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab3ffeb6819c1465c00a42016767344
https://pubmed.ncbi.nlm.nih.gov/35193494
https://pubmed.ncbi.nlm.nih.gov/35193494
Autor:
Jeremy Mason, Csaba Halmagyi, Aikaterini Chatzipli, Nathalie Conte, Steven B. Neuhauser, Helen Parkinson, Debra M. Krupke, Terrence F. Meehan, Galabina Yordanova, Carol J. Bult, Dale A. Begley, Abayomi Mosaku
Publikováno v:
Nucleic Acids Research
Patient-derived tumor xenograft (PDX) mouse models are a versatile oncology research platform for studying tumor biology and for testing chemotherapeutic approaches tailored to genomic characteristics of individual patients’ tumors. PDX models are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21150f1c0eb63f6b5b31dd780441e5a2
https://doi.org/10.1093/nar/gky984
https://doi.org/10.1093/nar/gky984
Autor:
Dale A. Begley, Mauricio Martinez, Nathalie Conte, Alex W. Follette, Steven B. Neuhauser, Helen Parkinson, Debra M. Krupke, Zinaida Perova, Ross Thorne, Csaba Halmagyi, Abayomi Mosaku, Carol J. Bult, Terrence F. Meehan, Jeremy Mason
Publikováno v:
Cancer Research. 81:LB017-LB017
Patient-derived tumor xenograft (PDX) models are a critical oncology platform for cancer research, drug development and personalized medicine. Because of the heterogeneous nature of PDXs repositories, finding models of interest is a challenge. The Ja
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0bc9a6a7277795ec1c4b24dd04fcbf3
https://doi.org/10.1158/1538-7445.am2021-lb017
https://doi.org/10.1158/1538-7445.am2021-lb017