Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Debra M. Eckert"'
Autor:
Dayton J. Goodell, Frank G. Whitby, Jerry E. Mellem, Ning Lei, Penelope J. Brockie, Aleksander J. Maricq, Debra M. Eckert, Christopher P. Hill, David M. Madsen, Andres V. Maricq
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113694- (2024)
Summary: N-methyl-D-aspartate (NMDA)-type ionotropic glutamate receptors have essential roles in neurotransmission and synaptic plasticity. Previously, we identified an evolutionarily conserved protein, NRAP-1, that is required for NMDA receptor (NMD
Externí odkaz:
https://doaj.org/article/0e71df12b48a4b31bdc42865b9f71de6
Autor:
Sun Jin Kim, Zhong Yao, Morgan C. Marsh, Debra M. Eckert, Michael S. Kay, Anna Lyakisheva, Maria Pasic, Aiyush Bansal, Chaim Birnboim, Prabhat Jha, Yannick Galipeau, Marc-André Langlois, Julio C. Delgado, Marc G. Elgort, Robert A. Campbell, Elizabeth A. Middleton, Igor Stagljar, Shawn C. Owen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Neutralisation assays are key to understanding immune responses to SARS-CoV-2 infection or vaccination. Here, the authors report a surrogate virus neutralization assay called Neu-SATiN, which measures neutralization directly from sera, and allows eas
Externí odkaz:
https://doaj.org/article/cb13b4c7a86945c89b15956fb496cbcb
Autor:
Amanda R. Smith, Matthew T. Weinstock, Amanda E. Siglin, Frank G. Whitby, J. Nicholas Francis, Christopher P. Hill, Debra M. Eckert, Michael J. Root, Michael S. Kay
Publikováno v:
Retrovirology, Vol 16, Iss 1, Pp 1-12 (2019)
Abstract Background PIE12-trimer is a highly potent d-peptide HIV-1 entry inhibitor that broadly targets group M isolates. It specifically binds the three identical conserved hydrophobic pockets at the base of the gp41 N-trimer with sub-femtomolar af
Externí odkaz:
https://doaj.org/article/afdf95a93d6b45de92747e1a8e5821fd
Autor:
Alexander A. Charbonneau, Debra M. Eckert, Colin C. Gauvin, Nathanael G. Lintner, C. Martin Lawrence
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1852 (2021)
Csa3 family transcription factors are ancillary CRISPR-associated proteins composed of N-terminal CARF domains and C-terminal winged helix-turn-helix domains. The activity of Csa3 transcription factors is thought to be controlled by cyclic oligoadeny
Externí odkaz:
https://doaj.org/article/fd9b55b2fdba4f8682238fa3dcfe7df8
Autor:
Danish Khan, Dongju Lee, Gulcin Gulten, Anup Aggarwal, Joshua Wofford, Inna Krieger, Ashutosh Tripathi, John W Patrick, Debra M Eckert, Arthur Laganowsky, James Sacchettini, Paul Lindahl, Vytas A Bankaitis
Publikováno v:
eLife, Vol 9 (2020)
Yeast Sfh5 is an unusual member of the Sec14-like phosphatidylinositol transfer protein (PITP) family. Whereas PITPs are defined by their abilities to transfer phosphatidylinositol between membranes in vitro, and to stimulate phosphoinositide signali
Externí odkaz:
https://doaj.org/article/33c5c7c3d2734eef83d198b262875ae8
Autor:
Sun Jin, Kim, Zhong, Yao, Morgan C, Marsh, Debra M, Eckert, Michael S, Kay, Anna, Lyakisheva, Maria, Pasic, Aiyush, Bansal, Chaim, Birnboim, Prabhat, Jha, Yannick, Galipeau, Marc-André, Langlois, Julio C, Delgado, Marc G, Elgort, Robert A, Campbell, Elizabeth A, Middleton, Igor, Stagljar, Shawn C, Owen
Publikováno v:
Nature communications. 13(1)
The COVID-19 pandemic triggered the development of numerous diagnostic tools to monitor infection and to determine immune response. Although assays to measure binding antibodies against SARS-CoV-2 are widely available, more specific tests measuring n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba6278c61b8ecbfe021563def3f1cb91
https://pubmed.ncbi.nlm.nih.gov/35778399
https://pubmed.ncbi.nlm.nih.gov/35778399
PKR activation by noncanonical ligands: a 5′-triphosphate requirement versus antisense contamination
Publikováno v:
RNA
Protein kinase RNA-activated (PKR) is an interferon-inducible kinase that is potently activated by long double-stranded RNA (dsRNA). In a previous study, we found that snoRNAs exhibit increased association with PKR in response to metabolic stress. Wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e998613305d9193a59d20c9efb1126c5
https://doi.org/10.1261/rna.071910.119
https://doi.org/10.1261/rna.071910.119
Autor:
James M Fulcher, Mark E. Petersen, Zachary S Cruz, J. Nicholas Francis, Michael T Jacobsen, Riley J. Giesler, Debra M. Eckert, Eric M Kawamoto, Michael S. Kay
Publikováno v:
Organic & Biomolecular Chemistry. 17:10237-10244
The application of solid-phase peptide synthesis and native chemical ligation in chemical protein synthesis (CPS) has enabled access to synthetic proteins that cannot be produced recombinantly, such as site-specific post-translationally modified or m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7157fdadd30f4a6df6e5fc54777c94c0
https://doi.org/10.1039/c9ob02012h
https://doi.org/10.1039/c9ob02012h
Autor:
Debra M. Eckert, Danish Khan, Dongju Lee, Ashutosh Tripathi, Paul A. Lindahl, James C. Sacchettini, Vytas A. Bankaitis, Gulcin Gulten, Anup Aggarwal, John W. Patrick, Inna Krieger, Arthur Laganowsky, Joshua D. Wofford
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Yeast Sfh5 is an unusual member of the Sec14-like phosphatidylinositol transfer protein (PITP) family. Whereas PITPs are defined by their abilities to transfer phosphatidylinositol between membranes in vitro, and to stimulate phosphoinositide signali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be619dc9ba0a9d9eb90a5565b125f393
https://doi.org/10.7554/elife.57081
https://doi.org/10.7554/elife.57081
Autor:
Vytas A. Bankaitis, Inna Krieger, Ashutosh Tripathi, Paul A. Lindahl, Anup Aggarwal, Gulcin Gulten, Danish Khan, James C. Sacchettini, Dongju Lee, Joshua D. Wofford, John W. Patrick, Arthur Laganowsky, Debra M. Eckert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b68d2019a44d418ee46f205f914c1ab7
https://doi.org/10.7554/elife.57081.sa2
https://doi.org/10.7554/elife.57081.sa2
