Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Debra L. Rigor"'
Publikováno v:
Vascular Pharmacology. 51:337-343
Combretastatin A-4 phosphate (CA4P) is a novel and promising anti-neoplastic agent. However, it is associated with transient hypertension in both animal and human models. In this study, we examined the potential cardiac toxicity and hypertensive effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b7e3572e5844d3f3e07fd4323cd682c
https://doi.org/10.1016/j.vph.2009.08.004
https://doi.org/10.1016/j.vph.2009.08.004
Autor:
Venkatesha Shivalingappa, Peter M. Kang, S. Ananth Karumanchi, Steven G. Achinger, Debra L. Rigor, Juan Carlos Ayus, Ravi Thadhani, Natalya Bodyak, Paul E. Kroeger, Qingen Ke, Yee-Shiuan Chen, Ruth R. Wu-Wong, Hector Tamez, Isaac E. Stillman
Publikováno v:
Proceedings of the National Academy of Sciences. 104:16810-16815
Observations in hemodialysis patients suggest a survival advantage associated with activated vitamin D therapy. Left ventricular (LV) structural and functional abnormalities are strongly linked with hemodialysis mortality. Here, we investigated wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d669acea2b02d9333a41f2eb02ec47f
https://doi.org/10.1073/pnas.0611202104
https://doi.org/10.1073/pnas.0611202104
Autor:
Yuchi Han, Natalya Bodyak, Debra L. Rigor, Peter M. Kang, Egbert Bisping, Yee-Shiuan Chen, William T. Pu
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 293:H829-H835
Uncoupling protein 2 (UCP2) is an inner mitochondrial membrane proton carrier that uncouples ATP synthesis. The aim of this study was to determine whether UCP2 plays a role in survival of adult rat cardiac myocytes. We first studied the effects of UC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2c35fe8eb552579440365cc3031fed
https://doi.org/10.1152/ajpheart.01409.2006
https://doi.org/10.1152/ajpheart.01409.2006
Autor:
Zhilin Liu, Peter M. Kang, Egbert Bisping, Yuchi Han, Debra L. Rigor, William T. Pu, Natalya Bodyak, Yee-Shiuan Chen
Publikováno v:
Circulation Research. 99:415-423
Caspase-9 is a critical regulator of mitochondria-mediated apoptosis. We found that adult cardiac myocytes, but not nonmyocytes, have high caspase-9 expression, and exhibit relative resistance to caspase-9–induced cell death. Thus, we hypothesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ed7298ab8967dccf110c653e4df03b
https://doi.org/10.1161/01.res.0000237387.05259.a5
https://doi.org/10.1161/01.res.0000237387.05259.a5
Autor:
Tetsuo Shioi, Julie R. McMullen, Debra L. Rigor, Peter M. Kang, Dmitry Ter-Ovanesyan, Jun H. Choi, Li Zhang, Zhiheng He, Seigo Izumo, George L. King, Soochan Bae, Natalya Bodyak
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 296(3)
The phosphoinositide 3-kinase (PI3-kinase)-protein kinase B (Akt) signaling pathway is essential in the induction of physiological cardiac hypertrophy. In contrast, protein kinase C beta2 (PKCbeta2) is implicated in the development of pathological ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e007b6fd3653622a9d7744ae03e5bc1
https://pubmed.ncbi.nlm.nih.gov/19122165
https://pubmed.ncbi.nlm.nih.gov/19122165
The role of caspase-independent apoptotic events in heart failure is largely unknown. The present study examined the response of apoptotic factors, which can function independently of caspase machinery including AIF, EndoG, and HtrA2/Omi to high salt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88d3846df8def38c326289378e856877
https://europepmc.org/articles/PMC1855196/
https://europepmc.org/articles/PMC1855196/
