Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Debra L. Hickman"'
Autor:
Patricia V. Turner, Debra L. Hickman, Judith van Luijk, Merel Ritskes-Hoitinga, Jan M. Sargeant, T. Miki Kurosawa, Takashi Agui, Vera Baumans, Woo Sung Choi, Yang-Kyu Choi, Paul A. Flecknell, Byeong H. Lee, Pedro J. Otaegui, Kathleen R. Pritchett-Corning, Keisuke Shimada
Publikováno v:
Frontiers in Veterinary Science, Vol 7 (2020)
Background: There has been increased concern about the suitability of CO2 as a method for euthanasia of laboratory mice and rats, including the potential discomfort, pain or distress that animals may experience prior to loss of consciousness; time to
Externí odkaz:
https://doaj.org/article/60a688d1cdda40cf869af78cd9ce6ed0
Autor:
Debra L. Hickman, Stephanie D. Fitz, Cristian S. Bernabe, Izabela F. Caliman, Melissa M. Haulcomb, Lauren M. Federici, Anantha Shekhar, Philip L. Johnson
Publikováno v:
Animals, Vol 6, Iss 8, p 45 (2016)
Current recommendations for the use of CO 2 as a euthanasia agent for rats require the use of gradual fill protocols (such as 10% to 30% volume displacement per minute) in order to render the animal insensible prior to exposure to levels of CO 2 that
Externí odkaz:
https://doaj.org/article/57c3932dca124d4b8418124769086fde
Autor:
Debra L Hickman
Publikováno v:
Journal of the American Association for Laboratory Animal Science. 62:274-278
Minimization of potential pain and distress of rodents undergoing euthanasia is a touchstone of veterinary clinical medicine. Evaluation of this issue in postweanling rodents has supported revisions to the AVMA (American Veterinary Medical Associatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd0211e0edce0b9d64f916b512979a59
https://doi.org/10.30802/aalas-jaalas-22-000103
https://doi.org/10.30802/aalas-jaalas-22-000103
Autor:
Debra L, Hickman
Publikováno v:
J Am Assoc Lab Anim Sci
When using an anesthetic overdose to euthanize laboratory rodents, a secondary method of euthanasia is recommended to ensure that the apparent death is irreversible. This secondary method usually is accomplished through the collection of tissues that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4afa56860b829668863924d462a33f
https://doi.org/10.30802/aalas-jaalas-21-000113
https://doi.org/10.30802/aalas-jaalas-21-000113
Publikováno v:
J Am Assoc Lab Anim Sci
Rotational outbred adult rats, phenotypically selected to prefer drinking alcohol ("P" rats) frequently present with selfinflicted wounds and ulcerative dermatitis, similar to that seen in C57BL/6 mice. Historically, veterinary interventions used to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb41a389e58dc9dfd3eff6e2c36e1d70
https://doi.org/10.30802/aalas-jaalas-20-000058
https://doi.org/10.30802/aalas-jaalas-20-000058
Publikováno v:
J Am Assoc Lab Anim Sci
Survival rodent surgery requires the use of sterile instruments for each animal, which can be challenging when performing multiple surgeries on batches of animals. Glass bead sterilizers (GBS) are widely considered to facilitate this practice by ster
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd024cdea87008f971bef09ee9ea6342
https://europepmc.org/articles/PMC9137293/
https://europepmc.org/articles/PMC9137293/
Autor:
Debra L Hickman
Publikováno v:
J Am Assoc Lab Anim Sci
Most studies evaluating methods of euthanasia to date have focused on the euthanasia of individual animals. However, larger chambers are commonly used to euthanize multiple cages of animals at once. This study evaluated the use of a commercially avai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ddcd21416590cd1aaeea994b7a68842
https://europepmc.org/articles/PMC8956221/
https://europepmc.org/articles/PMC8956221/
Publikováno v:
Journal of the American Association for Laboratory Animal Science. 58:119-125
Although social housing of mice generally is preferred, mice must be individually housed in some situations. In these cases, enhanced attention to environmental enrichment is encouraged, but few studies assess the wellbeing of mice provided various e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd6bb48d2f9a7de129a57b9052db7229
https://doi.org/10.30802/aalas-jaalas-17-000103
https://doi.org/10.30802/aalas-jaalas-17-000103
Autor:
Debra L. Hickman
Publikováno v:
Journal of the American Association for Laboratory Animal Science
The 2013 AVMA Guidelines on Euthanasia recommend the use of very-low or low flow rates of 100% carbon dioxide to euthanize small rodents. Although inhalation of high concentrations of carbon dioxide are generally recognized as painful in humans, whet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d60a1b75c5eafdd5d1f052caa5e3812
Publikováno v:
ILAR Journal. 60:252-269
The use of animal models remains critical in preclinical and translational research. The reliability of the animal models and aspects of their validity is likely key to effective translation of findings to medicine. However, despite considerable unif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5c92f492b2b31204544fe8256529f0
https://doi.org/10.1093/ilar/ilaa005
https://doi.org/10.1093/ilar/ilaa005