Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Debra L. Banville"'
Publikováno v:
Protein Expression and Purification. 11:86-94
Structural studies on soluble proteins using nuclear magnetic resonance (NMR) spectroscopy and other structural methods in general require large quantities of isotopically enriched proteins. Human interleukin-5 is a disulfide-linked homodimeric cytok
Autor:
Debra L, Banville
Publikováno v:
Current opinion in drug discoverydevelopment. 12(3)
The mining of information from the drug literature covers a broad set of disciplines that include chemistry, biology and medicine. It is not possible for any one scientist to keep up to date on the wide breadth of published pharmaceutical information
Publikováno v:
Journal of Molecular Biology. 219:585-590
The binding of spermine to the d(m 5 CGm 5 CGm 5 CG) duplex has been studied by proton and phosphorus nuclear magnetic resonance techniques in order to investigate the mobility and nature of spermine bound to the resulting Z -DNA complex. A character
Publikováno v:
Biochemistry. 29:9294-9304
The binding of mithramycin A to the d(A1T2G3C4A5T6) duplex was investigated by 1H NMR and found to be similar to that of its analogue chromomycin A3. In the presence of Mg2+, mithramycin binds strongly to d(ATGCAT)2. On the basis of the two-dimension
Autor:
Debra L. Banville
Publikováno v:
Pharmaceutical Data Mining: Approaches and Applications for Drug Discovery
It is easier to find too many documents on a life science topic than to find the right information inside these documents. With the application of text data mining to biological documents, it is no surprise that researchers are starting to look at ap
Autor:
Debra L. Banville
The First Book to Describe the Technical and Practical Elements of Chemical Text MiningExplores the development of chemical structure extraction capabilities and how to incorporate these technologies in daily research workFor scientific researchers,
Autor:
Gary Steelman, Cathy Dantzman, Robert Toms Jacobs, David Aharony, Willam E Palmer, Russell C. Mauger, Philip D. Edwards, Vernon Alford, Frederick J Brown, Megan Murphy, Jean M. Surian, Laura E Garcia-Davenport, Debra L. Banville, Russell Bialecki, Chris Allan Veale, James R. Damewood, Andrew Shaw, Kara K. Pine, Edward P. Vacek, William L. Rumsey
Publikováno v:
Bioorganicmedicinal chemistry letters. 10(17)
The cyclic peptide ANP 4-23 and the linear peptide analogue AP-811 have been shown to be selective ANP-CR antagonists. Via alanine scanning and truncation studies we sought to determine which residues in these molecules were important in their bindin