Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Debra L Robson"'
Autor:
Alexandra M Stoianov, Debra L Robson, Alexandra M Hetherington, Cynthia G Sawyez, Nica M Borradaile
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131269 (2015)
Elongation factor 1A-1 (eEF1A-1) has non-canonical functions in regulation of the actin cytoskeleton and apoptosis. It was previously identified through a promoter-trap screen as a mediator of fatty acid-induced cell death (lipotoxicity), and was fou
Externí odkaz:
https://doaj.org/article/bcb5f74d543d4e1db84f95f56925ccc0
Autor:
Nica M. Borradaile, Cynthia G. Sawyez, Alexandra M. Hetherington, Emma Zilberman, Debra L. Robson, Alexandra M. Stoianov
Publikováno v:
Cellular Physiology and Biochemistry, Vol 39, Iss 4, Pp 1648-1662 (2016)
Background/Aims: Nonalcoholic fatty liver disease (NAFLD) progression to fibrosis, cirrhosis and hepatocellular carcinoma, alters the cellular composition of this organ. During late-stage NAFLD, fibrotic and possibly cancerous cells can proliferate a
Autor:
Pak Chan, Debra L. Robson, Dominic K. T. Pang, Jelena Toma, Jennifer M. Hughes-Large, Nica M. Borradaile
Publikováno v:
Atherosclerosis. 237:696-704
Objective : Niacin (nicotinic acid) as a monotherapy can reduce vascular disease risk, but its mechanism of action remains controversial, and may not be dependent on systemic lipid modifying effects. Niacin has recently been shown to improve endothel
Autor:
Zengxuan Nong, Nica M. Borradaile, Cynthia G. Sawyez, Jelena Toma, Brian G. Sutherland, Dominic K. T. Pang, Debra L. Robson, J. Geoffrey Pickering
Publikováno v:
Pharmacology Research & Perspectives
Niacin can reduce vascular disease risk in individuals with metabolic syndrome, but in light of recent large randomized controlled trials outcomes, its biological actions and clinical utility remain controversial. Niacin can improve endothelial funct
Autor:
Debra L. Robson, Nica M. Borradaile, Alexandra M. Stoianov, Cynthia G. Sawyez, Alexandra M. Hetherington
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 6, p e0131269 (2015)
PLoS ONE, Vol 10, Iss 6, p e0131269 (2015)
Elongation factor 1A-1 (eEF1A-1) has non-canonical functions in regulation of the actin cytoskeleton and apoptosis. It was previously identified through a promoter-trap screen as a mediator of fatty acid-induced cell death (lipotoxicity), and was fou
Publikováno v:
Blood. 114:3042-3042
Abstract 3042 Poster Board II-1018 Clinical application of regenerative cell-based therapies for the treatment of ischemic vascular disease has proven challenging to implement due the involvement of multiple human cell types that co-ordinate angiogen
Publikováno v:
Blood. 114:2426-2426
Abstract 2426 Poster Board II-403 In the context of regenerative therapies for diabetes, the contributions of transplanted stem cells are not limited to the direct replacement of damaged beta cells. We previously established that transplanted murine
Autor:
Sarah A. Hohm, Marian J. Neelamkavil, Benjamin J. Capoccia, Debra L. Robson, Daniel C. Link, David A. Hess, Jan A. Nolta, Krysta Levac
Publikováno v:
Blood. 110:3716-3716
In the context of regenerative therapies, the contributions of transplanted stem cells are not limited to the direct replacement of damaged cells. Easily procured, post-natal bone marrow (BM) contains several colony-forming cell (CFC) lineages that p
Autor:
Alexandra M. Hetherington, Cynthia G. Sawyez, Emma Zilberman, Alexandra M. Stoianov, Debra L. Robson, Nica M. Borradaile
Publikováno v:
Cellular Physiology and Biochemistry, Vol 39, Iss 4, Pp 1648-1662 (2016)
Background/Aims: Nonalcoholic fatty liver disease (NAFLD) progression to fibrosis, cirrhosis and hepatocellular carcinoma, alters the cellular composition of this organ. During late-stage NAFLD, fibrotic and possibly cancerous cells can proliferate a
Externí odkaz:
https://doaj.org/article/b1356ecf499f4b52921152aac4bb28de