Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Debra K. Duso"'
Autor:
Rajeshwer S. Sankhala, Kerri G. Lal, Jaime L. Jensen, Vincent Dussupt, Letzibeth Mendez-Rivera, Hongjun Bai, Lindsay Wieczorek, Sandra V. Mayer, Michelle Zemil, Danielle A. Wagner, Samantha M. Townsley, Agnes Hajduczki, William C. Chang, Wei-Hung Chen, Gina C. Donofrio, Ningbo Jian, Hannah A. D. King, Cynthia G. Lorang, Elizabeth J. Martinez, Phyllis A. Rees, Caroline E. Peterson, Fabian Schmidt, Tricia J. Hart, Debra K. Duso, Lawrence W. Kummer, Sean P. Casey, Jazmean K. Williams, Shruthi Kannan, Bonnie M. Slike, Lauren Smith, Isabella Swafford, Paul V. Thomas, Ursula Tran, Jeffrey R. Currier, Diane L. Bolton, Edgar Davidson, Benjamin J. Doranz, Theodora Hatziioannou, Paul D. Bieniasz, Dominic Paquin-Proulx, William W. Reiley, Morgane Rolland, Nancy J. Sullivan, Sandhya Vasan, Natalie D. Collins, Kayvon Modjarrad, Gregory D. Gromowski, Victoria R. Polonis, Nelson L. Michael, Shelly J. Krebs, M. Gordon Joyce
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The repeat emergence of SARS-CoV-2 variants of concern (VoC) with decreased susceptibility to vaccine-elicited antibodies highlights the need to develop next-generation vaccine candidates that confer broad protection. Here we describe the an
Externí odkaz:
https://doaj.org/article/61dc74f1c5d84f64ac1178c032cab9f4
Autor:
Sapna Patel, Yasser Faraj, Debra K. Duso, William W. Reiley, Erik A. Karlsson, Stacey Schultz-Cherry, Michael Vajdy
Publikováno v:
Nutrients, Vol 9, Iss 5, p 516 (2017)
Non-replicating vaccines, such as those based on recombinant proteins, require adjuvants and delivery systems, which have thus far depended on mimicking pathogen danger signals and strong pro-inflammatory responses. In search of a safer and more effi
Externí odkaz:
https://doaj.org/article/26120ccab2d044ada7287a70f7606d3c
Autor:
Matthew A. Cole, Sebastian Molnar, Michelle Zemil, Tricia J. Lang, Jiae Kim, Misook Choe, Joshua M. Carmen, Clayton Smith, Elizabeth J. Martinez, Morgane Rolland, Patrick M. McTamney, Debra K. Duso, Wei-Hung Chen, Zuzana Villar, William W. Reiley, Therese Oertel, Nelson L. Michael, Rajeshwer S. Sankhala, Gary R. Matyas, Neelakshi Gohain, Christopher P. Karch, Connor Whalen, Mark T. Esser, Val Nd, Shelly J. Krebs, Elaine B. Morrison, Htet Khanh, Victoria R. Polonis, Alexander R. A. Anderson, Michael Gordon Joyce, Saravanan Rajan, Caroline E. Peterson, Dussupt, Ursula Tran, Weimin Wu, James Brett Case, Aslaa Ahmed, Chandrika B. Kannadka, Shikha Shrivastava, Ousman Jobe, Akshaya Ganesh, Shania E. Muncil, Michael S. Diamond, Lindsay Wieczorek, Agnes Hajduczki, Caitlin Kuklis, Letzibeth Mendez-Rivera, Yifan Li, Kayvon Modjarrad, Paul V. Thomas, William C. Chang, Gregory D. Gromowski, Larry W. Kummer, Sandrine Soman, Rita E. Chen, Mangala Rao, Zoltan Beck, Lorean Rosado, David McCurdy, Currier
Publikováno v:
Cell Reports
bioRxiv
article-version (status) pre
article-version (number) 1
bioRxiv
article-version (status) pre
article-version (number) 1
The need for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) next-generation vaccines has been highlighted by the rise of variants of concern (VoCs) and the long-term threat of emerging coronaviruses. Here, we design and characterize fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc82f4148d7044467785a1335ca4d7c9
https://pubmed.ncbi.nlm.nih.gov/34919799
https://pubmed.ncbi.nlm.nih.gov/34919799
Plague is a rapidly lethal human disease caused by the bacterium Yersinia pestis. This study demonstrated that the Y. pestis plasminogen activator Pla, a protease that promotes fibrin degradation, thwarts T cell-mediated defense against fully virulen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f8d627459508794ccf5a7e520f9b09
https://europepmc.org/articles/PMC6479024/
https://europepmc.org/articles/PMC6479024/
Autor:
Yasser Faraj, Debra K. Duso, Michael Vajdy, Stacey Schultz-Cherry, William W. Reiley, Erik A. Karlsson, Sapna Patel
Publikováno v:
Nutrients
Nutrients; Volume 9; Issue 5; Pages: 516
Nutrients, Vol 9, Iss 5, p 516 (2017)
Nutrients; Volume 9; Issue 5; Pages: 516
Nutrients, Vol 9, Iss 5, p 516 (2017)
Non-replicating vaccines, such as those based on recombinant proteins, require adjuvants and delivery systems, which have thus far depended on mimicking pathogen danger signals and strong pro-inflammatory responses. In search of a safer and more effi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be150528800406eb2845c460290ab329
http://europepmc.org/articles/PMC5452246
http://europepmc.org/articles/PMC5452246
Autor:
David Gailani, Isis Mullarky-Kanevsky, Jr Shiuan Lin, Lawrence W. Kummer, Nigel Mackman, James Hill, Michelle A. Parent, Andras Gruber, Debra K. Duso, Frank M. Szaba, Michael Tighe, Deyan Luo, Stephen T. Smiley
Publikováno v:
The Journal of Immunology. 190:4149-4161
The Gram-negative bacterium Yersinia pestis causes plague, a rapidly progressing and often fatal disease. The formation of fibrin at sites of Y. pestis infection supports innate host defense against plague, perhaps by providing a nondiffusible spatia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ae17fba2dfac35cdccedf57984b3d9c
https://doi.org/10.4049/jimmunol.1203253
https://doi.org/10.4049/jimmunol.1203253
Publikováno v:
The Journal of Immunology. 185:4535-4544
With age, peripheral naive CD4 T cells become both longer lived and functionally impaired and they express reduced levels of Bim, a proapoptotic Bcl family member. In this study, we show that reduced Bim expression by naive CD4 T cells intrinsically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b322a38a94b671752cae7e82522790eb
https://doi.org/10.4049/jimmunol.1001668
https://doi.org/10.4049/jimmunol.1001668
Autor:
Amanda L. Buck, Susan L. Swain, Laura Haynes, Lawrence L. Johnson, Gail E. Huston, Hirotake Tsukamoto, Karen Clise-Dwyer, Debra K. Duso
Publikováno v:
Proceedings of the National Academy of Sciences. 106:18333-18338
With age, T-cell generation from the thymus is much reduced, yet a substantial naïve T-cell pool is maintained even in aged animals, suggesting that naïve T cells either persist longer or turn over faster to maintain T-cell homeostasis. We found th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::337dcedb024d61c4dc169a3ae7f6ad82
https://doi.org/10.1073/pnas.0910139106
https://doi.org/10.1073/pnas.0910139106
Autor:
Deborah M. Brown, Javed N. Agrewala, Susan L. Swain, Gail E. Huston, Nancy M. Lepak, Debra K. Duso
Publikováno v:
Journal of Biological Chemistry. 282:6106-6115
Recent studies suggest that effector T cells generated by immune responses migrate to multiple non-lymphoid sites, even those without apparent expression of antigen or inflammation. To investigate the ability of distinct CD4(+) T lymphocyte subsets t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc71429e9f755d585699b9bd482e065d
https://doi.org/10.1074/jbc.m608266200
https://doi.org/10.1074/jbc.m608266200
Publikováno v:
Nature Immunology. 2:705-710
Whether memory T lymphocytes are derived directly from effector T cells or via a separately controlled pathway has long been debated. Here we present evidence that, after adoptive transfer, a large fraction of in vitro--derived effector CD4(+) T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e09e0c98fadbd59715d0404e75d3d8b
https://doi.org/10.1038/90643
https://doi.org/10.1038/90643