Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Debra J. Warejcka"'
Publikováno v:
Molecular Vision
Purpose Previous research in our laboratory indicated that prothrombin and other coagulation enzymes required to activate prothrombin to thrombin are synthesized by the cornea and that apoptotic human corneal stromal cells can provide a surface for p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ce5c4e01634e914eed3a598aec8ffb81
https://pubmed.ncbi.nlm.nih.gov/32818017
https://pubmed.ncbi.nlm.nih.gov/32818017
Autor:
Stephanie Gillespie, Lingyan Wang, Audrey M. Bernstein, Sally S. Twining, Richard N. Bohnsack, Debra J. Warejcka, Nancy M. Dahms
Publikováno v:
Investigative Ophthalmology & Visual Science. 55:7697-7708
Insulin-like growth factor 2 receptor (IGF2R) associates with ligands that influence wound healing outcomes. However, the expression pattern of IGF2R and its role in the cornea is unknown.Human keratocytes were isolated from donor corneas. Fibroblast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8efc0f229a94c0012d3170a484044b5c
https://doi.org/10.1167/iovs.14-15179
https://doi.org/10.1167/iovs.14-15179
Autor:
Sally S. Twining, Debra J. Warejcka, Michael P. Endsley, Steven L. Gonias, Yong Deng, Yanqiu Hu, Xiaolin He, Ming Zhang
Publikováno v:
Journal of Biological Chemistry. 286:24599-24607
Maspin is a non-inhibitory serine protease inhibitor (serpin) that influences many cellular functions including adhesion, migration, and invasion. The underlying molecular mechanisms that facilitate these actions are still being elucidated. In this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd576700e1da1da48f8cec1e28711154
https://doi.org/10.1074/jbc.m111.235788
https://doi.org/10.1074/jbc.m111.235788
Autor:
Janice M. Burke, Debra J. Warejcka, Sally S. Twining, William J. O'Brien, Chatri Ngamkitidechakul
Publikováno v:
Journal of Biological Chemistry. 278:31796-31806
Maspin, an ov-serpin, inhibits tumor invasion and induces cell adhesion to extracellular matrix molecules. Here, we use maspin/ovalbumin chimeric proteins and the maspin reactive site loop (RSL) peptide to characterize the role of the RSL in maspin-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::953dc51990c611aaf35ff51ecd186c21
https://doi.org/10.1074/jbc.m302408200
https://doi.org/10.1074/jbc.m302408200
Autor:
Zhongbiao Wang, Walter H. Newman, Sandra K. Leeper-Woodford, Debra J. Warejcka, Kristina Detmer
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 281:H661-H668
Because inflammatory processes may promote the development of atherosclerosis, we examined the activation of cytokine genes in rat vascular smooth muscle cells in vitro after treatment with bacterial lipopolysaccharide (LPS). Interleukin-1 (IL-1), IL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d19ef5fd287f68cba214b7ee9e2813
https://doi.org/10.1152/ajpheart.2001.281.2.h661
https://doi.org/10.1152/ajpheart.2001.281.2.h661
Publikováno v:
Critical Care Medicine. 28:3593-3598
OBJECTIVES: Beta-adrenergic receptor agonists such as isoproterenol inhibit production of tumor necrosis factor (TNF)-alpha in a number of cell types. Because the heart is a source of TNF-alpha, we hypothesized that isoproterenol would inhibit cardia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ce1d0188783f23435ce23ae1ca0f47
https://doi.org/10.1097/00003246-200011000-00004
https://doi.org/10.1097/00003246-200011000-00004
Autor:
Kenneth R. Smart, Debra J. Warejcka, Manuel R. Castresana, Martin L. Dalton, Jerry G. Webb, Walter H. Newman
Publikováno v:
The American Surgeon. 66:947-951
Recent evidence suggests that inflammatory cytokines, particularly tumor necrosis factor a (TNF-α), may play a role in heart disease. Elevated plasma levels of the cytokine have been reported in congestive heart failure and severe angina and after m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50d8ebd5186af95701b60823b3f1c390
https://doi.org/10.1177/000313480006601008
https://doi.org/10.1177/000313480006601008
Publikováno v:
Journal of Surgical Research. 65:135-138
Transforming growth factor-beta (TGF-beta) is an important factor in regulating the inflammatory response and the production of extracellular matrix by fibroblasts. These two processes are linked in the formation of fibrous adhesions after abdominal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b906bb63574882e5437cfd71e8f988
https://doi.org/10.1006/jsre.1996.0355
https://doi.org/10.1006/jsre.1996.0355
Autor:
Sally S. Twining, Debra J. Warejcka, Jarrod W. Barnes, Jennifer M. Simpliciano, Richard Steet
Publikováno v:
The Journal of biological chemistry. 287(10)
Latent TGF-β1 was one of the first non-lysosomal glycoproteins reported to bear mannose 6-phosphate (Man-6-P) residues on its N-glycans. Prior studies have suggested that this sugar modification regulates the activation of latent TGF-β1 by allowing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cd3dbe2fcc3b0c8c16010de1061b9de
https://pubmed.ncbi.nlm.nih.gov/22262853
https://pubmed.ncbi.nlm.nih.gov/22262853
Publikováno v:
Experimental eye research. 93(5)
Maspin, an inhibitor of cell migration and a stimulator of adhesion of cells to the ECM, is synthesized and released by corneal keratocytes into the extracellular matrix. When the cornea is wounded, the quiescent stromal keratocytes underlying the wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ffd2e23142a2404db3b6dd07c84250
https://pubmed.ncbi.nlm.nih.gov/21810423
https://pubmed.ncbi.nlm.nih.gov/21810423