Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Debra J. Knisley"'
Biological structures and phenomena often operate at multiple scales, and investigating important biological problems effectively often involves understanding these different scales and how they interact. However, the biological data often look very
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edb56666828b9a0a8d79669b21b8452b
https://doi.org/10.1016/b978-0-12-814066-6.00001-5
https://doi.org/10.1016/b978-0-12-814066-6.00001-5
Autor:
Samuel Kakraba, Debra J. Knisley
Publikováno v:
JOURNAL OF ADVANCES IN BIOTECHNOLOGY. 6:780-786
Cystic fibrosis is one of the most prevalent inherited diseases. This disease is caused by a mutation in a membrane protein, the cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is known to function as a chloride channel that regulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cf45a403fc74531398de16f9db98fbb
https://doi.org/10.24297/jbt.v6i1.4013
https://doi.org/10.24297/jbt.v6i1.4013
Publikováno v:
Computational Biology Journal. 2013:1-9
Cystic fibrosis is one of the most common inherited diseases and is caused by a mutation in a membrane protein, the cystic fibrosis transmembrane conductance regulator (CFTR). This protein serves as a chloride channel and regulates the viscosity of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::627576b8716a805ce9a121451408d20a
https://doi.org/10.1155/2013/938169
https://doi.org/10.1155/2013/938169
Publikováno v:
Advances in Bioinformatics, Vol 2011 (2011)
Advances in Bioinformatics
Advances in Bioinformatics
Machine learning was applied to a challenging and biologically significant protein classification problem: the prediction of avonoid UGT acceptor regioselectivity from primary sequence. Novel indices characterizing graphical models of residues were p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78f7f05e042783906b449090a2698a90
https://doi.org/10.1155/2011/506583
https://doi.org/10.1155/2011/506583
Publikováno v:
CBE Life Sciences Education
We describe how a team approach that we developed as a mentoring strategy can be used to recruit, advance, and guide students to be more interested in the interdisciplinary field of mathematical biology, and lead to success in undergraduate research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37914a7ec294b2d88673d3e5edc966de
http://europepmc.org/articles/PMC3164564
http://europepmc.org/articles/PMC3164564
Autor:
Jeff Knisley, Debra J. Knisley
Publikováno v:
BMC Proceedings
Background: We represent the protein structure of scTIM with a graph-theoretic model. We construct a hierarchical graph with three layers - a top level, a midlevel and a bottom level. The top level graph is a representation of the protein in which it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2374056bd050b0431918cda6ee4610f2
https://doi.org/10.1186/1753-6561-8-s2-s7
https://doi.org/10.1186/1753-6561-8-s2-s7
Publikováno v:
ISRN Bioinformatics
The prediction of secondary RNA folds from primary sequences continues to be an important area of research given the significance of RNA molecules in biological processes such as gene regulation. To facilitate this effort, graph models of secondary s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276bd684cdc9daac2630f2bca058ce4a
Autor:
Debra J. Knisley
Publikováno v:
Journal of Graph Theory. 18:59-71
A graph G of order n satisfies the neighborhood condition NCk > s if any collection of k independent vertices is collectively adjacent to more than s vertices. Given a family H of graphs, the decomposition class β(H) is the family of graphs B with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38c3af92914a15edddb28d8d87a48c05
https://doi.org/10.1002/jgt.3190180107
https://doi.org/10.1002/jgt.3190180107
Publikováno v:
BMC Bioinformatics, Vol 11, Iss Suppl 6, p S21 (2010)
BMC Bioinformatics
BMC Bioinformatics
Background Determining the secondary structure of RNA from the primary structure is a challenging computational problem. A number of algorithms have been developed to predict the secondary structure from the primary structure. It is agreed that there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf13c706183ec840ce79861aa4a54079
https://doi.org/10.1186/1471-2105-11-s6-s21
https://doi.org/10.1186/1471-2105-11-s6-s21
Publikováno v:
BMC Bioinformatics, Vol 7, Iss 1, p 108 (2006)
BMC Bioinformatics
BMC Bioinformatics
Background It has become increasingly apparent that a comprehensive database of RNA motifs is essential in order to achieve new goals in genomic and proteomic research. Secondary RNA structures have frequently been represented by various modeling met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16761c0d09211234c4165649bfe60e5
http://www.biomedcentral.com/1471-2105/7/108
http://www.biomedcentral.com/1471-2105/7/108