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pro vyhledávání: '"Debra Hidayetoglu"'
Autor:
Archana Chaudhry, Gary Bora, Robin Roof, Jiansu Zhang, Natasha M. Kablaoui, Maura E. Charlton, Bradley Snyder, Wendy M. Habeski, Cheryl Li, Snahel Patel, Hyunsuk Min, Brian M. Campbell, Douglas S. Johnson, Debra Hidayetoglu
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:5689-5693
The discovery of the CNS-penetrant and selective α 2C adrenergic receptor antagonist N -{2-[4-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1,4]diazepan-1-yl]-ethyl}-2-phenoxy-nicotinamide, 13 is described. Structure–activity studies demonstrate the