Výsledky vyhledávání - "Debra Hidayetoglu"

Identification and SAR around N-{2-[4-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1,4]diazepan-1-yl]-ethyl}-2-phenoxy-nicotinamide, a selective α2C adrenergic receptor antagonist

Autor: Archana Chaudhry, Gary Bora, Robin Roof, Jiansu Zhang, Natasha M. Kablaoui, Maura E. Charlton, Bradley Snyder, Wendy M. Habeski, Cheryl Li, Snahel Patel, Hyunsuk Min, Brian M. Campbell, Douglas S. Johnson, Debra Hidayetoglu

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 18:5689-5693

The discovery of the CNS-penetrant and selective α 2C adrenergic receptor antagonist N -{2-[4-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1,4]diazepan-1-yl]-ethyl}-2-phenoxy-nicotinamide, 13 is described. Structure–activity studies demonstrate the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ae90347ee6fdc4b6bf4aff67fb2c11
https://doi.org/10.1016/j.bmcl.2008.08.055

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Akademický článek

Evaluating the relationship between clinical and demographic characteristics of insulin-using people with diabetes and their health outcomes: a cluster analysis application.

Autor: Eby, Elizabeth L.¹ (AUTHOR) ebye@lilly.com, Edwards, Alison² (AUTHOR), Meadows, Eric¹ (AUTHOR), Lipkovich, Ilya¹ (AUTHOR), Benneyworth, Brian D.¹ (AUTHOR), Snow, Kenneth² (AUTHOR)

Publikováno v: BMC Health Services Research. 7/8/2021, Vol. 21 Issue 1, p1-15. 15p. 3 Diagrams, 5 Charts, 3 Graphs.

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A phase 1b study of crenigacestat (LY3039478) in combination with gemcitabine and cisplatin or gemcitabine and carboplatin in patients with advanced or metastatic solid tumors.

Autor: Massard, C., Cassier, P. A., Azaro, A., Anderson, B., Yuen, E., Yu, D., Oakley III, G., Benhadji, K. A., Pant, S., Oakley, G 3rd

Publikováno v: Cancer Chemotherapy & Pharmacology; Oct2022, Vol. 90 Issue 4, p335-344, 10p

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Akademický článek

Ultra rapid lispro (URLi) shows accelerated pharmacokinetics and greater reduction in postprandial glucose versus Humalog® in patients with type 1 diabetes mellitus in a randomized, double‐blind meal test early‐phase study.

Autor: Kazda, Christof, Leohr, Jennifer, Liu, Rong, Reddy, Shobha, Dellva, Mary Anne, Loh, Mei Teng, Hardy, Thomas, Plum‐Mörschel, Leona

Publikováno v: Diabetes, Obesity & Metabolism; Feb2022, Vol. 24 Issue 2, p196-203, 8p

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Akademický článek

Ultra rapid lispro (URLi) shows faster pharmacokinetics and reduces postprandial glucose excursions versus Humalog® in patients with type 2 diabetes mellitus in a randomized, controlled crossover meal test early‐phase study.

Autor: Leohr, Jennifer, Kazda, Christof, Liu, Rong, Reddy, Shobha, Dellva, Mary Anne, Matzopoulos, Mark, Loh, Mei Teng, Hardy, Thomas, Klein, Oliver, Kapitza, Christoph

Publikováno v: Diabetes, Obesity & Metabolism; Feb2022, Vol. 24 Issue 2, p187-195, 9p

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Akademický článek

A phase 1b study of the Notch inhibitor crenigacestat (LY3039478) in combination with other anticancer target agents (taladegib, LY3023414, or abemaciclib) in patients with advanced or metastatic solid tumors.

Autor: Azaro, Analia, Massard, Christophe, Tap, William D., Cassier, Philippe A., Merchan, Jaime, Italiano, Antoine, Anderson, Bailey, Yuen, Eunice, Yu, Danni, Oakley III, Gerard, Benhadji, Karim A., Pant, Shubham

Publikováno v: Investigational New Drugs; Aug2021, Vol. 39 Issue 4, p1089-1098, 10p

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A Randomized, Two-Way Crossover Study to Evaluate the Pharmacokinetics of Caffeine Delivered Using Caffeinated Chewing Gum Versus a Marketed Caffeinated Beverage in Healthy Adult Volunteers.

Autor: Sadek, Paul, Xiao Pan, Shepherd, Phil, Malandain, Elise, Carney, John, Coleman, Hugh

Publikováno v: Journal of Caffeine Research; Dec2017, Vol. 7 Issue 4, p125-132, 8p

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