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pro vyhledávání: '"Debra Cheng"'
Autor:
Hyewon Phee, Byron B Au-Yeung, Olga Pryshchep, Kyle Leonard O'Hagan, Stephanie Grace Fairbairn, Maria Radu, Rachelle Kosoff, Marianne Mollenauer, Debra Cheng, Jonathan Chernoff, Arthur Weiss
Publikováno v:
eLife, Vol 3 (2014)
The molecular mechanisms that govern thymocyte development and maturation are incompletely understood. The P21-activated kinase 2 (Pak2) is an effector for the Rho family GTPases Rac and Cdc42 that regulate actin cytoskeletal remodeling, but its role
Externí odkaz:
https://doaj.org/article/0f47d51dd4a94e00b110b8cfba0b5ab7
Publikováno v:
The Journal of Immunology. 186:64.15-64.15
The tyrosine kinase ZAP-70 is critical for the activation of signal pathways downstream of the TCR. We previously generated a transgenic mouse expressing a ZAP-70 mutant (ZAP-70AS) that is selectively inhibited by a PP1 analog, called 3-methyl benzyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6a181cc6dc47ba57f84482d667b02df
https://doi.org/10.4049/jimmunol.186.supp.64.15
https://doi.org/10.4049/jimmunol.186.supp.64.15