Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Debra Ann Fadool"'
Publikováno v:
Membranes, Vol 13, Iss 2, p 151 (2023)
Odor detection and discrimination in mammals is known to be initiated by membrane-bound G-protein-coupled receptors (GPCRs). The role that the lipid membrane may play in odor discrimination, however, is less well understood. Here, we used model membr
Externí odkaz:
https://doaj.org/article/ab3845bf76294f9e864da27994e44f03
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Neuromodulation influences neuronal processing, conferring neuronal circuits the flexibility to integrate sensory inputs with behavioral states and the ability to adapt to a continuously changing environment. In this original research report, we broa
Externí odkaz:
https://doaj.org/article/63c376ec162242fb92faa174b0576af1
Publikováno v:
Physiological Reports, Vol 7, Iss 20, Pp n/a-n/a (2019)
Abstract Voluntary exercise is frequently employed as an intervention for obesity. The voltage‐gated potassium channel Kv1.3 is also receiving attention as a therapeutic target for obesity, in addition to potential therapeutic capabilities for neur
Externí odkaz:
https://doaj.org/article/c95bd5b9afa042b08a548497d274149b
Autor:
Christopher P. Kovach, Dolly eAl Koborssy, Zhenbo eHuang, Brandon Michael Chelette, James Michael Fadool, Debra Ann Fadool
Publikováno v:
Frontiers in Physiology, Vol 7 (2016)
Gene-targeted deletion of the potassium channel Kv1.3 (Kv1.3-/-) results in ‘Super-smeller’ mice with a sensory phenotype that includes an increased olfactory ability linked to changes in olfactory circuitry, increased abundance of olfactory cili
Externí odkaz:
https://doaj.org/article/eebd43b1a6bb40199ebe81c9df137bb6
Autor:
Thomas Gerald Mast, Debra Ann Fadool
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31978 (2012)
Sensory deprivation induces dramatic morphological and neurochemical changes in the olfactory bulb (OB) that are largely restricted to glomerular and granule layer interneurons. Mitral cells, pyramidal-like neurons, are resistant to sensory-deprivati
Externí odkaz:
https://doaj.org/article/afeedd85d2d642eeb068653ddd3dd102
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24921 (2011)
Sixty-five percent of Americans are over-weight. While the neuroendocrine controls of energy homeostasis are well known, how sensory systems respond to and are impacted by obesity is scantily understood. The main accepted function of the olfactory sy
Externí odkaz:
https://doaj.org/article/736c497a2a3d451f84c866deff859c49
Autor:
Liang Du, Shannon Helsper, Neda Arabzadeh Nosratabad, Wentao Wang, Debra Ann Fadool, Catherine Amiens, Samuel Grant, Hedi Mattoussi
Publikováno v:
Bioconjug Chem
Magnetic resonance imaging, MRI, relying on (19)F nuclei has attracted much attention, because the isotopes exhibit a high gyromagnetic ratio (comparable to that of protons) and have 100% natural abundance. Furthermore, due to the very low traces of
Autor:
Daniel R. Landi Conde, Carley M. Huffstetler, Ashley M. Loeven, Destinee N. Gatlin, Debra Ann Fadool, Meizhu Qi, Brandon M. Chelette
Publikováno v:
The Journal of Physiology. 600:1473-1495
Key points Obesity can disrupt the structure and function of organ systems, including the olfactory system that is important for food selection and satiety. We designed dietary treatments in mice such that mice received fat, but the total calories pr
Autor:
Louis John Kolling, Roberta Tatti, Troy Lowry, Ashley M. Loeven, James M. Fadool, Debra Ann Fadool
Publikováno v:
J Neurosci
Metabolic state can alter olfactory sensitivity, but it is unknown whether the activity of the olfactory bulb (OB) may fine tune metabolic homeostasis. Our objective was to use CRISPR gene editing in male and female mice to enhance the excitability o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af332a0c0cae604812a1cc0048f1a6b
https://europepmc.org/articles/PMC9337614/
https://europepmc.org/articles/PMC9337614/
Autor:
Destinee Gatlin, Carley Huffstetler, Claudia Cedeno, Brigitte Cochran, Alexis Cox, Tyla Dolezel, Ezabelle Franck, Camilla May, Nicholas Maycut, Claudia Silver, Debra Ann Fadool
Publikováno v:
The FASEB Journal. 36