Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Debra Akin"'
Autor:
Chunjuan Song, Sayak K Mitter, Xiaoping Qi, Eleni Beli, Haripriya V Rao, Jindong Ding, Colin S Ip, Hongmei Gu, Debra Akin, William A Dunn, Catherine Bowes Rickman, Alfred S Lewin, Maria B Grant, Michael E Boulton
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171940 (2017)
p62 is a scaffolding adaptor implicated in the clearance of protein aggregates by autophagy. Reactive oxygen species (ROS) can either stimulate or inhibit NFκB-mediated gene expression influencing cellular fate. We studied the effect of hydrogen per
Externí odkaz:
https://doaj.org/article/4bf9aaa6427c4582993782460d6aff9c
Autor:
Carl M. Feldherr, Debra Akin
Publikováno v:
BioTechniques, Vol 32, Iss 6, Pp 1288-1296 (2002)
Here we demonstrate that fluorescein-labeled BSA conjugated with a mixture of nuclear import and export signals can be used to evaluate export activity. The method is based on the assumption that the intracellular distribution of the labeled conjugat
Externí odkaz:
https://doaj.org/article/d5b94212c58946969f0ea792d67a96d1
Autor:
Leticia Reyes, Eileen Eiler-McManis, Paulo H Rodrigues, Amandeep S Chadda, Shannon M Wallet, Myriam Bélanger, Amanda G Barrett, Sophie Alvarez, Debra Akin, William A Dunn, Ann Progulske-Fox
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74230 (2013)
P. gingivalis (Pg), a causative agent of chronic generalized periodontitis, has been implicated in promoting cardiovascular disease. Expression of lipoprotein gene PG0717 of Pg strain W83 was found to be transiently upregulated during invasion of hum
Externí odkaz:
https://doaj.org/article/a2a6acf696b042eebc75e99aac2ca292
Autor:
Paulo H Rodrigues, Leticia Reyes, Amandeep S Chadda, Myriam Bélanger, Shannon M Wallet, Debra Akin, William Dunn, Ann Progulske-Fox
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52606 (2012)
Both epidemiologic and experimental findings suggest that infection with Porphyromonas gingivalis exacerbates progression of atherosclerosis. As P. gingivalis exhibits significant strain variation, it is reasonable that different strains possess diff
Externí odkaz:
https://doaj.org/article/84d544ce840849fcb780f674c8edefae
Autor:
Jindong Ding, Xiaoping Qi, Haripriya Vittal Rao, Haoyu Mao, Chunjuan Song, Catherine Bowes Rickman, Sayak K. Mitter, Maria B. Grant, Alfred S. Lewin, Michael E. Boulton, Debra Akin, William A. Dunn
Publikováno v:
Autophagy. 10:1989-2005
Autophagic dysregulation has been suggested in a broad range of neurodegenerative diseases including age-related macular degeneration (AMD). To test whether the autophagy pathway plays a critical role to protect retinal pigmented epithelial (RPE) cel
Autor:
Brian K. Law, Jae-Sung Kim, Pouran Habibzadegah-Tari, Xiao Ming Yin, Min Li, S. Keisin Wang, Nicole A. Horenstein, David A. Ostrov, William A. Dunn, Debra Akin
Publikováno v:
Autophagy
Autophagy has been implicated in the progression and chemoresistance of various cancers. In this study, we have shown that osteosarcoma Saos-2 cells lacking ATG4B, a cysteine proteinase that activates LC3B, are defective in autophagy and fail to form
Publikováno v:
Molecular Vision
Purpose The specialized corneal epithelium requires differentiated properties, specific for its role at the anterior surface of the eye. Thus, tight maintenance of the differentiated qualities of the corneal epithelial is essential. Pinin (PNN) is an
Autor:
Ann Progulske-Fox, Robert A. Burne, Patricia J. Simpson-Haidaris, Lin Zeng, Myriam Bélanger, Debra Akin, Paulo Henrique Mazza Rodrigues, Jacqueline Abranches, William A. Dunn
Publikováno v:
Oral Microbiology and Immunology. 24:141-145
Introduction Dissemination of oral bacteria into the bloodstream has been associated with eating, oral hygiene, and dental procedures; including tooth extraction, endodontic treatment, and periodontal surgery. Recently, studies identified Streptococc
Publikováno v:
Journal of Cell Science. 115:2997-3005
In this report we investigated the activity of vertebrate nuclear transport factors in a primitive organism, Amoeba proteus, to better understand evolutionary changes in the transport mechanisms of organisms expected to have different requirements fo
Autor:
Jindong Ding, Debra Akin, Catherine Bowes Rickman, Chunjuan Song, Eleni Beli, Sayak K. Mitter, Michael E. Boulton, William A. Dunn, Colin S. Ip, Maria B. Grant, Alfred S. Lewin, Hongmei Gu, Haripriya Vittal Rao, Xiaoping Qi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 2, p e0171940 (2017)
PLoS ONE, Vol 12, Iss 2, p e0171940 (2017)
p62 is a scaffolding adaptor implicated in the clearance of protein aggregates by autophagy. Reactive oxygen species (ROS) can either stimulate or inhibit NFκB-mediated gene expression influencing cellular fate. We studied the effect of hydrogen per