Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Debra A. Hullett"'
Autor:
Rodolfo Alejandro, David A. Baidal, Nancy Radke, Jon S. Odorico, Luis A. Fernandez, Juan S. Danobeitia, D. Hirsch, Michael R. Rickels, Dixon B. Kaufman, Debra A. Hullett, Ali Naji, Matthew S. Hanson, Camillo Ricordi
Publikováno v:
American Journal of Transplantation. 12:1275-1289
The objective of this study was to identify predictors of insulin independence and to establish the best clinical tools to follow patients after pancreatic islet transplantation (PIT). Sequential metabolic responses to intravenous (I.V.) glucose (I.V
Autor:
Hans W. Sollinger, William J. Burlingham, Jose R. Torrealba, Partha Dutta, Debra A. Hullett, Donald A. Harn, Drew A. Roenneburg
Publikováno v:
Transplantation. 90:1071-1078
Background. Lacto-N-fucopentaose III (LNFPIII) is a pentasaccharide containing the Lewis x trisaccharide that is found on schistosome eggs and in breast milk. LNFPIII conjugates suppress host immune responses and have therapeutic efficacy in mouse mo
Autor:
Nancy Radke, Rodolfo Alejandro, D. Hirsch, Juan S. Danobeitia, Matthew S. Hanson, Jon S. Odorico, Camillo Ricordi, Luis A. Fernandez, Debra A. Hullett
Publikováno v:
Diabetes, Obesity and Metabolism. 12:994-1003
Aims: Pancreatic islet transplantation (PIT) represents a potential curative treatment for patients with type 1 diabetes, but only 10-15% of patients remain insulin independent 5 years post-transplant. It is not known whether intrinsic insulin resist
Publikováno v:
American Journal of Physiology-Renal Physiology. 295:F707-F716
We hypothesized that heat shock protein 27 (HSP27), a small heat shock protein with actin-remodeling properties, is involved in the pathogenesis of kidney tubulointerstitial fibrosis. We first examined its expression in the rat unilateral ureteral ob
Publikováno v:
Journal of Vascular Research. 45:365-374
Background: The success of peripheral vein grafts is limited by intimal hyperplasia. Transforming growth factor (TGF)-β1 has effects on cell proliferation, apoptosis and extracellular matrix synthesis. We have previously observed positive changes in
Publikováno v:
Journal of Vascular Surgery. 43(5):1028-1036
BackgroundThe main cause of occlusion and vein graft failure after peripheral and coronary arterial reconstruction is intimal hyperplasia. Transforming growth factor β-1 (TGF-β1) is a pleiotropic cytokine known to have powerful effects on cell grow
Autor:
Arjang Djamali, Lynn M. Jacobson, Debra A. Hullett, Jenifer Sprague, Rebecca J. Muehrer, Jon A. Weidanz, Thomas J. Thekkumkara, Bryan N. Becker, Vaughan Wittman, Maurizio Chiriva-Internati
Publikováno v:
Kidney International. 67(6):2134-2142
AT1R blockade reduces IFN-γ production in lymphocytes in vivo and in vitro.BackgroundType 1 angiotensin II (Ang II) receptor (AT1R) signaling induces proinflammatory responses. Recent studies suggest that T lymphocytes express AT1R; yet the effects
Publikováno v:
Transplantation. 79:1645-1657
BACKGROUND Heat shock protein (HSP) 27 plays a cytoprotective role through its antioxidant, antiapoptotic, and actin-stabilizing properties during cell stress. The authors hypothesized that HSP27 is involved in chronic allograft nephropathy (CAN), a
Autor:
Terry D. Oberley, Jon S. Odorico, Jaime M. Ochoada, Katharine M. Lang, Lynn M. Jacobson, Debra A. Hullett, Brenda Kahan
Publikováno v:
Diabetes. 52:2016-2024
Embryonic stem (ES) cells differentiating in vitro reproduce many facets of early embryonic development, including the expression of developmentally regulated transcription factors and the differentiation of multipotent precursor cells. ES cells were
Autor:
Debra A. Hullett, Randal A. Wolff, V. Emily Stark, Thomas F. Warner, Jeffrey J. Tomas, John R. Hoch, Jimmy L. Kim
Publikováno v:
Journal of Vascular Research. 40:266-275
Objective: Myofibroblasts are present transiently in normal healing wounds. However, they have been found to persist in the stroma of neoplasms, fibrotic conditions and other pathological settings. In rat vein grafts, we have observed the prolonged p