Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Debra A Tokarz"'
Autor:
Drake W. Phelps, Ashley A. Fletcher, Ivan Rodriguez-Nunez, Michele R. Balik-Meisner, Debra A. Tokarz, David M. Reif, Dori R. Germolec, Jeffrey A. Yoder
Publikováno v:
Journal of Immunotoxicology, Vol 17, Iss 1, Pp 94-104 (2020)
Currently, assessment of the potential immunotoxicity of a given agent involves a tiered approach for hazard identification and mechanistic studies, including observational studies, evaluation of immune function, and measurement of susceptibility to
Externí odkaz:
https://doaj.org/article/5718c6c16ab0489ea04c142e9bedcb9e
Autor:
Christopher L. Mariani, Carolyn J. Nye, Debra A. Tokarz, Lauren Green, Jeanie Lau, Natalia Zidan, Peter J. Early, Julien Guevar, Karen R. Muñana, Natasha J. Olby, Sarita Miles
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 33, Iss 6, Pp 2701-2708 (2019)
Abstract Background Cerebrospinal fluid (CSF) lactate is frequently used as a biomarker in humans with inflammatory central nervous system (CNS) disorders including bacterial meningitis and autoimmune disorders such as multiple sclerosis. Hypothesis
Externí odkaz:
https://doaj.org/article/3629ff08b2224544ba52b6e5864f8597
Autor:
Hunter N. Bomba, Kevin T. Sheets, Alain Valdivia, Simon Khagi, Laura Ruterbories, Christopher L. Mariani, Luke B. Borst, Debra A. Tokarz, Shawn D. Hingtgen
Publikováno v:
Bioengineering & Translational Medicine, Vol 6, Iss 1, Pp n/a-n/a (2021)
Abstract In this study, we take an important step toward clinical translation by generating the first canine‐induced neural stem cells (iNSCs). We explore key aspects of scale‐up, persistence, and safety of personalized iNSC therapy in autologous
Externí odkaz:
https://doaj.org/article/a38f818c20b3442cb3bef3ef71b9e4d1
Autor:
Arjun Mohan, Nicole Neequaye, Anagha Malur, Eman Soliman, Matthew McPeek, Nancy Leffler, David Ogburn, Debra A. Tokarz, Warren Knudson, Sina A. Gharib, Lynn M. Schnapp, Barbara P. Barna, Mary Jane Thomassen
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
BackgroundSarcoidosis is a chronic inflammatory disease of unknown cause characterized by granuloma formation. Mechanisms for chronic persistence of granulomas are unknown. Matrix Metalloproteinase-12 (MMP12) degrades extracellular matrix elastin and
Externí odkaz:
https://doaj.org/article/bcb3df98e0c3456bbe6ce0ea1f1596d9
Autor:
Erin M. Quist, Shambhunath Choudhary, Richard Lang, Debra A. Tokarz, Mark Hoenerhoff, Jonathan Nagel, Jeffrey I. Everitt
Publikováno v:
Toxicol Pathol
The 2022 annual National Toxicology Program Satellite Symposium, entitled “Pathology Potpourri,” was held in Austin, Texas at the Society of Toxicologic Pathology’s 40th annual meeting during a half-day session on Sunday, June 19. The goal of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dfa317378990d74fcdaf1884629bfd1
https://doi.org/10.1177/01926233221124825
https://doi.org/10.1177/01926233221124825
Autor:
Gregory A. Krane, Keith R. Shockley, David E. Malarkey, Andrew D. Miller, C. Ryan Miller, Debra A. Tokarz, Heather L. Jensen, Kyathanahalli S. Janardhan, Matthew Breen, Christopher L. Mariani
Publikováno v:
Veterinary and Comparative Oncology. 20:881-889
Histopathological evaluation of tumours is a subjective process, but studies of inter-pathologist agreement are uncommon in veterinary medicine. The Comparative Brain Tumour Consortium (CBTC) recently published diagnostic criteria for canine gliomas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c98f0edcf882fd97781f6bf3a7ad1d
https://doi.org/10.1111/vco.12853
https://doi.org/10.1111/vco.12853
Autor:
Kazuhito Sai, Aoi Nakanishi, Kimberly M. Scofield, Debra A. Tokarz, Keith E. Linder, Todd J. Cohen, Jun Ninomiya-Tsuji
Publikováno v:
Journal of Cell Science. 136
Neuroinflammation is causally associated with Alzheimer's disease (AD) pathology. Reactive glia cells secrete various neurotoxic factors that impair neuronal homeostasis eventually leading to neuronal loss. Although the glial activation mechanism in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4949dbd3ae57b487be003c0947a9155b
https://doi.org/10.1242/jcs.260102
https://doi.org/10.1242/jcs.260102
Autor:
Jerrold M. Ward, Susan A. Elmore, Michelle C. Cora, Erin M. Quist, Shambhunath Choudhary, Quinci Plumlee, Gregory A. Krane, Andrew W. Suttie, Debra A Tokarz
Publikováno v:
Toxicol Pathol
The 2021 annual National Toxicology Program (NTP) Satellite Symposium, entitled “Pathology Potpourri,” was the 20th anniversary of the symposia and held virtually on June 25th, in advance of the Society of Toxicologic Pathology’s 40th annual me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a63cb92dc074b6d399145ef4d335cb9
https://doi.org/10.1177/01926233211043497
https://doi.org/10.1177/01926233211043497
Autor:
Brita Kilburg-Basnyat, Debra A. Tokarz, Sanjay Varikuti, Jennifer H. Madenspacher, Robert M. Tighe, Myles X Hodge, Michael B. Fessler, Sky W Reece, Kymberly M. Gowdy, Seddon Y. Thomas, Katelyn Dunigan-Russell, Donald N. Cook, Bin Luo
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Asthma is a common respiratory disease currently affecting more than 300 million worldwide and is characterized by airway inflammation, hyperreactivity, and remodeling. It is a heterogeneous disease consisting of corticosteroid-sensitive T-helper cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e7f28b0bbf7b93cec00d20a5d5c2e9
https://doi.org/10.1165/rcmb.2020-0007oc
https://doi.org/10.1165/rcmb.2020-0007oc
Autor:
Mark F. Cesta, Vivian S. Chen, Gargi Srivastava, Rajesh Ugalmugle, Kristen Hobbie, Heath C. Thomas, Thomas J Steinbach, Caroll A. Co, Emily Singletary, Keith R. Shockley, Debra A Tokarz, Avinash Lokhande, Torrie A. Crabbs
Publikováno v:
Toxicol Pathol
Rodent progressive cardiomyopathy (PCM) encompasses a constellation of microscopic findings commonly seen as a spontaneous background change in rat and mouse hearts. Primary histologic features of PCM include varying degrees of cardiomyocyte degenera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::833d2007c619bd75ef678d9f5a898ebb
https://doi.org/10.1177/0192623320972614
https://doi.org/10.1177/0192623320972614