Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Debra A MacKenzie"'
Autor:
Dominique N Price, Amber A McBride, Martina Anton, Donna F Kusewitt, Jeffrey P Norenberg, Debra A MacKenzie, Todd A Thompson, Pavan Muttil
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0169107 (2016)
Lung cancer has the highest mortality rate of any tissue-specific cancer in both men and women. Research continues to investigate novel drugs and therapies to mitigate poor treatment efficacy, but the lack of a good descriptive lung cancer animal mod
Externí odkaz:
https://doaj.org/article/d6246baf7cc9492692dea8a85eb76f80
Autor:
Alexandra M Fajardo, Debra A MacKenzie, Sarah L Olguin, John K Scariano, Ian Rabinowitz, Todd A Thompson
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151525 (2016)
Tocopherylquinone (TQ), the oxidation product of alpha-tocopherol (AT), is a bioactive molecule with distinct properties from AT. In this study, AT and TQ are investigated for their comparative effects on growth and androgenic activity in prostate ca
Externí odkaz:
https://doaj.org/article/1fc0516e6b5d423ea55125d54d003d20
Autor:
Jodi R. Schilz, Erica J. Dashner-Titus, Li Luo, Karen A. Simmons, Debra A. MacKenzie, Laurie G. Hudson
Publikováno v:
Toxicology Reports, Vol 8, Iss , Pp 1917-1929 (2021)
Communities in the western region of the United States experience environmental exposure to metal mixtures from living in proximity to numerous unremediated abandoned uranium mines. Metals including arsenic and uranium co-occur in and around these si
Externí odkaz:
https://doaj.org/article/44c8671c56b640f9b37012ae77a6ee2a
Autor:
Jodi R. Schilz, Erica J. Dashner-Titus, Karen A. Simmons, Esther Erdei, Alicia M. Bolt, Debra A. MacKenzie, Laurie G. Hudson
Publikováno v:
Toxicol Appl Pharmacol
Uranium is a naturally occurring element found in the environment as a mixture of isotopes with differing radioactive properties. Enrichment of mined material results in depleted uranium waste with substantially reduced radioactivity but retains the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe2cbc326ca74034e49d4abd65478b55
https://pubmed.ncbi.nlm.nih.gov/36152676
https://pubmed.ncbi.nlm.nih.gov/36152676
Publikováno v:
Acta Haematologica. 122:230-237
Background/Aims: Despite a sophisticated understanding of the hematopoietic developmental program at the transcriptional level, our understanding of the role of E3 ubiquitin ligases remains underdeveloped. The E3 ubiquitin ligase, GRAIL (RNF128), is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba0cf2d06920484364563d89bd2b3c7
https://doi.org/10.1159/000253591
https://doi.org/10.1159/000253591
Publikováno v:
Human Immunology. 61:1320-1331
We have previously shown that hyperbaric oxygen culture (HOC [95% O 2 , 5% CO 2 , 25 psi]) is an effective pretransplant tissue-modification technique that results in long-term allograft survival and the induction of systemic immune tolerance in a mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b22d79591057b7a35984b3b817e05a7d
https://doi.org/10.1016/s0198-8859(00)00214-7
https://doi.org/10.1016/s0198-8859(00)00214-7
Autor:
C. Garrison Fathman, Christine M. Seroogy, Amanda Timmel, Martha L. Jennens-Clough, Debra A. MacKenzie, Jill Schartner, Jack T. Lin
Publikováno v:
The Journal of biological chemistry. 282(13)
GRAIL (gene related to anergy in lymphocytes) is an ubiquitin-protein isopeptide ligase (E3) ubiquitin ligase necessary for the induction of CD4(+) T cell anergy in vivo. We have extended our previous studies to characterize the expression pattern of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed6c8507f93e89376bb699b35ddb9b20
https://pubmed.ncbi.nlm.nih.gov/17259178
https://pubmed.ncbi.nlm.nih.gov/17259178
Publikováno v:
Transplantation proceedings. 35(4)
Human fetal pancreas (HFP) is a potential source of islets for the treatment of diabetes mellitus with the potential for growth and differentiation after transplantation. However, because of the small mass of a given HFP, multiple donors would be req
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::986bb73af9ba0e45f3481c3c0c5cc5dd
https://pubmed.ncbi.nlm.nih.gov/12826206
https://pubmed.ncbi.nlm.nih.gov/12826206
Publikováno v:
Transplantation proceedings. 35(4)
Human fetal pancreas (HFP) is a potential source of transplantable islets for the treatment of type 1 insulin-dependent diabetes mellitus (IDDM). Pretransplant culture techniques such as long-term culture, high-oxygen culture, UVB irradiation, and lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::934d4ee74eda7167058455497c6473fc
https://pubmed.ncbi.nlm.nih.gov/12826204
https://pubmed.ncbi.nlm.nih.gov/12826204
Publikováno v:
Fetal Islet Transplantation ISBN: 9781461358169
It is estimated that approximately 1.4 million people in the United States suffer from insulin dependent diabetes mellitus (IDDM). Daily insulin therapy and whole organ pancreas transplantation are the only treatments currently available. Results of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6aaab462d6b13c31e1c74080a018a736
https://doi.org/10.1007/978-1-4615-1981-2_3
https://doi.org/10.1007/978-1-4615-1981-2_3
