Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Deborah W. McCarthy"'
Autor:
Heather M. Bigott, Buck E. Rogers, Deborah W. McCarthy, Joonyoung Kim, Terry L. Sharp, Debbie Della Manna, Michael J. Welch
Publikováno v:
Bioconjugate Chemistry. 14:756-763
The gastrin-releasing peptide receptor (GRPR) is overexpressed on a variety of carcinomas and has been the target for detection and treatment of these neoplasms in animals. In particular, analogues of the tetradecapeptide bombesin (BN) have been radi
Autor:
Yasuhisa Fujibayashi, Deborah W. McCarthy, Hideo Saji, Atsushi Obata, Yoshiharu Yonekura, Michael J. Welch, Shingo Kasamatsu
Publikováno v:
Nuclear Medicine and Biology. 30:535-539
(64)Cu is a useful radiotracer for positron emission tomography (PET) and a promising radiotherapy agent for the treatment of cancer. Recently, (64)Cu-labeled radiopharmaceuticals were reported to be useful for internal radiation therapy as well as P
Autor:
Nona, Adonai, Nora, Adonai, Khoi N, Nguyen, Joseph, Walsh, M, Iyer, Tatsushi, Toyokuni, Michael E, Phelps, Timothy, McCarthy, Deborah W, McCarthy, Sanjiv Sam, Gambhir
Publikováno v:
Proceedings of the National Academy of Sciences. 99:3030-3035
We have used copper-64-pyruvaldehyde-bis( N 4 -methylthiosemicarbazone) ( 64 Cu–PTSM) to radiolabel cells ex vivo for in vivo positron-emission tomography (PET) imaging studies of cell trafficking in mice and for eventual application in patients. 2
Autor:
Yasuhisa Fujibayashi, Lynne Jones, Michael J. Welch, Yoshiharu Yonekura, Deborah W. McCarthy, Terry L. Sharp, Carolyn J. Anderson, Cathy S. Cutler
Publikováno v:
Nuclear Medicine and Biology. 26:117-121
Copper labeled diacetyl-bis(N4-methylthiosemicarbazone) (Cu-ATSM) is a promising agent for the imaging of hypoxic tissues. In the present study 64Cu(t1/2 = 12.8 h) labeled Cu-ATSM was used in combination with 11C (t1/2 = 20.3 min) labeled acetate as
Autor:
Zoltan Kovacs, A. Dean Sherry, Ramunas J. Motekaitis, Carolyn J. Anderson, Michael J. Welch, Teresa M. Jones-Wilson, Arthur E. Martell, Kim A. Deal, Deborah W. McCarthy
Publikováno v:
Nuclear Medicine and Biology. 25:523-530
The use of copper radioisotopes in imaging and therapy applications has created a greater need for bifunctional chelates (BFCs) for complexing copper radioisotopes to biomolecules. It has been demonstrated that the charge and lipophilicity of the Cu-
Autor:
Laura A. Bass, R.E. Shefer, Carolyn J. Anderson, Deborah W. McCarthy, Robert E. Klinkowstein, Michael J. Welch, Cathy S. Cutler, William H. Margeneau
Publikováno v:
Nuclear Medicine and Biology. 24:35-43
Copper-64 (T 1/2 = 12.7 h) is an intermediate-lived positron-emitting radionuclide that is a useful radiotracer for positron emission tomography (PET) as well as a promising radiotherapy agent for the treatment for cancer. Currently, copper-64 suitab
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 44:S817-S819
Since September 1999, Washington University has been funded as a Research Resource in Radionuclide Research by the National Cancer Institute. The goals of the Resource include providing novel radionuclides for collaborative research and other applica
Autor:
Terry L. Sharp, Buck E. Rogers, Michael J. Welch, D. Della Manna, Richard Kirkman, Joonyoung Kim, Deborah W. McCarthy
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 44:S81-S83
Autor:
Heather M. Bigott, Michael J. Welch, Frank Wüst, Julie L. Dahlheimer, Deborah W. McCarthy, David Piwnica-Worms
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 44:S119-S121
Technetium-99m is a widely used radioisotope in nuclear medicine. The characteristics of this generator-produced radionuclide (T1/2 = 6 h, Eγ = 140.5 keV, Iγ = 87.2 %) make it an ideal isotope for single photon emission computed tomography (SPECT).
Publikováno v:
Positron Emission Tomography ISBN: 9781852337988
There are many possible metal-based positron-emitting radionuclides that can be utilized in positron tomography. At the present time, the most promising nuclides are copper, gallium, and yttrium. It is highly likely that radiopharmaceuticals labeled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc690c1c9cfa41e62b1a1924a4cb0628
https://doi.org/10.1007/1-84628-007-9_11
https://doi.org/10.1007/1-84628-007-9_11