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pro vyhledávání: '"Deborah Trem"'
Autor:
Georges C. Frech, Deborah Trem, Ted D. Adams, David A. Frank, Victor Abkevich, Kirsten Timms, Gongping He, Robyn Riley, Srikanth Jammulapati, Steven C. Hunt, Donna Shattuck, Deanna L. Russell, Jerry S. Lanchbury, Richard E. Gress, Mark H. Skolnick, Chris Neff, Thanh Tran, Diana Iliev, Alexander Gutin, Steven Stone
Publikováno v:
Human Molecular Genetics. 15:2709-2720
The molecular etiology of obesity predisposition is largely unknown. Here, we present evidence that genetic variation in TBC1D1 confers risk for severe obesity in females. We identified a coding variant (R125W) in TBC1D1 that segregated with the dise