Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Deborah Stroka"'
Autor:
Ting Zhang, Alisa Ambrodji, Huixing Huang, Kelly J Bouchonville, Amy S Etheridge, Remington E Schmidt, Brianna M Bembenek, Zoey B Temesgen, Zhiquan Wang, Federico Innocenti, Deborah Stroka, Robert B Diasio, Carlo R Largiadèr, Steven M Offer
Publikováno v:
eLife, Vol 13 (2024)
Enhancers are critical for regulating tissue-specific gene expression, and genetic variants within enhancer regions have been suggested to contribute to various cancer-related processes, including therapeutic resistance. However, the precise mechanis
Externí odkaz:
https://doaj.org/article/f486b24826a64551bd611deb78f24793
Autor:
Roberta Esposito, Andrés Lanzós, Tina Uroda, Sunandini Ramnarayanan, Isabel Büchi, Taisia Polidori, Hugo Guillen-Ramirez, Ante Mihaljevic, Bernard Mefi Merlin, Lia Mela, Eugenio Zoni, Lusine Hovhannisyan, Finn McCluggage, Matúš Medo, Giulia Basile, Dominik F. Meise, Sandra Zwyssig, Corina Wenger, Kyriakos Schwarz, Adrienne Vancura, Núria Bosch-Guiteras, Álvaro Andrades, Ai Ming Tham, Michaela Roemmele, Pedro P. Medina, Adrian F. Ochsenbein, Carsten Riether, Marianna Kruithof-de Julio, Yitzhak Zimmer, Michaela Medová, Deborah Stroka, Archa Fox, Rory Johnson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Long noncoding RNAs (lncRNAs) are linked to cancer via pathogenic changes in their expression levels. Yet, it remains unclear whether lncRNAs can also impact tumour cell fitness via function-altering somatic “driver” mutations. To search
Externí odkaz:
https://doaj.org/article/ac68b1f51d77424ab680971f8fdf0575
Autor:
Manuel O. Jakob, Daniel Spari, Daniel Sànchez Taltavull, Lilian Salm, Bahtiyar Yilmaz, Rémi Doucet Ladevèze, Catherine Mooser, David Pereyra, Ye Ouyang, Theresa Schmidt, Irene Mattiola, Patrick Starlinger, Deborah Stroka, Franziska Tschan, Daniel Candinas, Georg Gasteiger, Christoph S.N. Klose, Andreas Diefenbach, Mercedes Gomez de Agüero, Guido Beldi
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112269- (2023)
Summary: It is generally believed that environmental or cutaneous bacteria are the main origin of surgical infections. Therefore, measures to prevent postoperative infections focus on optimizing hygiene and improving asepsis and antisepsis. In a larg
Externí odkaz:
https://doaj.org/article/c73c0b7cf4aa4763ab2085992ed320f3
Autor:
Roberta Esposito, Andrés Lanzós, Tina Uroda, Sunandini Ramnarayanan, Isabel Büchi, Taisia Polidori, Hugo Guillen-Ramirez, Ante Mihaljevic, Bernard Mefi Merlin, Lia Mela, Eugenio Zoni, Lusine Hovhannisyan, Finn McCluggage, Matúš Medo, Giulia Basile, Dominik F. Meise, Sandra Zwyssig, Corina Wenger, Kyriakos Schwarz, Adrienne Vancura, Núria Bosch-Guiteras, Álvaro Andrades, Ai Ming Tham, Michaela Roemmele, Pedro P. Medina, Adrian F. Ochsenbein, Carsten Riether, Marianna Kruithof-de Julio, Yitzhak Zimmer, Michaela Medová, Deborah Stroka, Archa Fox, Rory Johnson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/4e6d43c141ad486fbe88bece10724bab
Autor:
Joel Zindel, Jonas Mittner, Julia Bayer, Simon L. April-Monn, Andreas Kohler, Ysbrand Nusse, Michel Dosch, Isabel Büchi, Daniel Sanchez-Taltavull, Heather Dawson, Mercedes Gomez de Agüero, Kinji Asahina, Paul Kubes, Andrew J. Macpherson, Deborah Stroka, Daniel Candinas
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Abdominal surgery can often lead to complications including the formation of peritoneal adhesions and the molecular mechanisms underlying this process are still unknown. Here, the authors suggest that bacterial contamination drives adhesion formation
Externí odkaz:
https://doaj.org/article/1b8f340ac5fd494498184c00669b8081
Autor:
Zhong-Yi Wang, Adrian Keogh, Annick Waldt, Rachel Cuttat, Marilisa Neri, Shanshan Zhu, Sven Schuierer, Alexandra Ruchti, Christophe Crochemore, Judith Knehr, Julie Bastien, Iwona Ksiazek, Daniel Sánchez-Taltavull, Hui Ge, Jing Wu, Guglielmo Roma, Stephen B. Helliwell, Deborah Stroka, Florian Nigsch
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Fibrosis is characterized by the excessive production of collagen and other extracellular matrix (ECM) components and represents a leading cause of morbidity and mortality worldwide. Previous studies of nonalcoholic steatohepatitis (NASH) wi
Externí odkaz:
https://doaj.org/article/1e0a2f5a8461417ea4b3375f454caf3c
Publikováno v:
Bio-Protocol, Vol 12, Iss 16 (2022)
Abdominal surgeries are frequently associated with the development of post-surgical adhesions. These are irreversible fibrotic scar bands that appear between abdominal organs and the abdominal wall. Patients suffering from adhesions are at risk of se
Externí odkaz:
https://doaj.org/article/9ecbd5e81eff4d71b389d136c87ba569
Autor:
Edgar Ontsouka, Mariana Schroeder, Linda Ok, Cathy Vaillancourt, Deborah Stroka, Christiane Albrecht
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9511 (2023)
Bile acids (BAs) are natural ligands for several receptors modulating cell activities. BAs are synthesized via the classic (neutral) and alternative (acidic) pathways. The classic pathway is initiated by CYP7A1/Cyp7a1, converting cholesterol to 7α-h
Externí odkaz:
https://doaj.org/article/30ffd520c16a46708aa637dbf3c9edd2
Autor:
Nicolas Melin, Tural Yarahmadov, Daniel Sanchez-Taltavull, Fabienne E. Birrer, Tess M. Brodie, Benoît Petit, Andrea Felser, Jean-Marc Nuoffer, Matteo Montani, Marie-Catherine Vozenin, Evelyn Herrmann, Daniel Candinas, Daniel M. Aebersold, Deborah Stroka
Publikováno v:
JHEP Reports, Vol 4, Iss 7, Pp 100508- (2022)
Background & Aims: High-dose irradiation is an essential tool to help control the growth of hepatic tumors, but it can cause radiation-induced liver disease (RILD). This life-threatening complication manifests itself months following radiation therap
Externí odkaz:
https://doaj.org/article/0749ed9dab7d4d07a64da355fcaf6f38
Autor:
Nicolas Melin, Daniel Sánchez-Taltavull, René Fahrner, Adrian Keogh, Michel Dosch, Isabel Büchi, Yitzhak Zimmer, Michaela Medová, Guido Beldi, Daniel M. Aebersold, Daniel Candinas, Deborah Stroka
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-12 (2021)
Abstract The toll-like receptor 5 (TLR5) agonist, CBLB502/Entolimod, is a peptide derived from bacterial flagellin and has been shown to protect against radiation-induced tissue damage in animal models. Here we investigated the protective mechanism o
Externí odkaz:
https://doaj.org/article/9fb567e82f4d416b850bee9442bbda8c