Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Deborah Stefanova"'
Autor:
Bo Qiao, Mika Jormakka, T Alex Ruwe, Sharraya Aschemeyer, Kyle R. Vieth, Tomas Ganz, Bryan Mackenzie, Deborah Stefanova, Albert C. Sek, Stefano Rivella, Erika V. Valore, Carla Casu, Elizabeta Nemeth, Grace Jung
Publikováno v:
Blood. 131:899-910
Nonclassical ferroportin disease (FD) is a form of hereditary hemochromatosis caused by mutations in the iron transporter ferroportin (Fpn), resulting in parenchymal iron overload. Fpn is regulated by the hormone hepcidin, which induces Fpn endocytos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe457e05e36c922303764756b0ef709
https://doi.org/10.1182/blood-2017-05-786590
https://doi.org/10.1182/blood-2017-05-786590
Autor:
Tomas Ganz, Shelley Campeau, Piotr Ruchala, Yonca Bulut, Romney M. Humphries, Antoan Raychev, Elizabeta Nemeth, Deborah Stefanova, Jaime G. Deville
Publikováno v:
Infection and immunity, vol 86, iss 7
Iron is an essential micronutrient for most microbes and their hosts. Mammalian hosts respond to infection by inducing the iron-regulatory hormone hepcidin, which causes iron sequestration and a rapid decrease in the plasma and extracellular iron con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b49115ec4cb5e83ab488ba05db751a
https://pubmed.ncbi.nlm.nih.gov/29735522
https://pubmed.ncbi.nlm.nih.gov/29735522
Autor:
Tomas Ganz, João Arezes, Mikael Skurnik, Victoria Gabayan, Piotr Ruchala, Barbara Jane Dillon, Antoan Raychev, Deborah Stefanova, Marcus A. Horwitz, Yonca Bulut, Elizabeta Nemeth
Publikováno v:
Blood. 130(3)
The iron-regulatory hormone hepcidin is induced early in infection, causing iron sequestration in macrophages and decreased plasma iron; this is proposed to limit the replication of extracellular microbes, but could also promote infection with macrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe4b599b8e76e0ddee2234982bfb005
https://pubmed.ncbi.nlm.nih.gov/28729331
https://pubmed.ncbi.nlm.nih.gov/28729331
Autor:
João Arezes, Deborah Stefanova, Marcus A. Horwitz, Tomas Ganz, Borna Mehrad, Elizabeta Nemeth, Yonca Bulut, Barbara Jane Dillon, Kathryn R Michels
Publikováno v:
Blood. 128:260-260
The production of the iron-regulatory hormone hepcidin is strongly induced by infection and inflammation, causing hypoferremia. This is proposed to be a host defense response to limit microbial replication. Patients with hereditary hemochromatosis or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d334a5fdc1d989147e769610b72555cf
https://doi.org/10.1182/blood.v128.22.260.260
https://doi.org/10.1182/blood.v128.22.260.260