Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Deborah S Hunter"'
Autor:
Sarah K Tasian, Deborah S Hunter, I-Ming L Chen, Richard C Harvey, Andrew J. Carroll, Elizabeth Wagner, Shalini C Reshmi, Michael J Borowitz, Brent L. Wood, Jeannie Daniel, Meenakshi Devidas, Elizabeth A. Raetz, Stephen P. Hunger, Albert Assad, Mignon L. Loh
Publikováno v:
Blood. 140:6117-6118
Autor:
Ruben A. Mesa, Jean-Jacques Kiladjian, Srdan Verstovsek, Haifa Kathrin Al-Ali, Jason Gotlib, Heinz Gisslinger, Richard Levy, Andres Siulnik, Vikas Gupta, Mahmudul Khan, John F. DiPersio, Mari McQuitty, John V. Catalano, Deborah S. Hunter, Laurent Knoops, Michael Deininger, Francisco Cervantes, Carole Miller, Alessandro M. Vannucchi, Richard T. Silver, Tiziano Barbui, Moshe Talpaz, Giovanni Barosi, Elliott F. Winton, Estella Mendeson, Jimmie H. Harvey, Murat O. Arcasoy, Elizabeth Hexner, Roger M. Lyons, Ronald Paquette, Azra Raza, William Sun, Victor Sandor, Hagop M. Kantarjian, Claire Harrison
Publikováno v:
Haematologica, Vol 99, Iss 2 (2014)
Prior to Janus kinase inhibitors, available therapies for myelofibrosis were generally supportive and did not improve survival. This analysis compares efficacy outcomes of patients with myelofibrosis in the control arms (placebo [n=154] and best avai
Externí odkaz:
https://doaj.org/article/23c64710c3624182a69371f30b69787f
Autor:
Robert Manges, Zev A. Wainberg, Philip J. Stella, Victor Sandor, J. Marc Pipas, Deborah S. Hunter, Seaborn M. Wade, Lance Leopold, Stephanie Ann Wagner, Herbert Hurwitz, Johanna C. Bendell, John Nemunaitis, Jason Clark, William M. Garrett, Nikhil Uppal, J. Thaddeus Beck, Richard S. Levy
Publikováno v:
Journal of Clinical Oncology. 33:4039-4047
Purpose Patients with advanced pancreatic adenocarcinoma have a poor prognosis and limited second-line treatment options. Evidence suggests a role for the Janus kinase (JAK)/signal transducer and activator of transcription pathway in the pathogenesis
Autor:
Paola Guglielmelli, Carole B. Miller, Mark M. Jones, Francesco Passamonti, Dany Habr, Simon Durrant, Fabrizio Pane, Pierre Zachee, Deborah S. Hunter, Mahmudul Khan, Srdan Verstovsek, William Sun, Jingjin Li, Jean-Jacques Kiladjian, Tamás Masszi, Martin Griesshammer, Claire N. Harrison
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d8c09071019779bb873a600db6ed2f1
http://hdl.handle.net/11588/721797
http://hdl.handle.net/11588/721797
Autor:
Moshe Talpaz, Peter O'Neill, Jason Clark, Srdan Verstovsek, Ronald Paquette, Lynda Foltz, Deborah S. Hunter, Vikas Gupta, Timothy Burn, Paul Bernard Coughlin, John Mascarenhas, Michael R. Savona, A. Robert Turner, Elliott F. Winton, Albert Assad, Ronald Hoffman
Combined Janus kinase 1 (JAK1) and JAK2 inhibition therapy effectively reduces splenomegaly and symptom burden related to myelofibrosis but is associated with dose-dependent anemia and thrombocytopenia. In this open-label phase II study, we evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06226f8a926f3d39bdee40ee8c5931f9
https://europepmc.org/articles/PMC5286940/
https://europepmc.org/articles/PMC5286940/
Autor:
Bruno Martino, Hui-Ling Zhen, Francesco Passamonti, Pierre Zachee, Ruben A. Mesa, Deborah S. Hunter, Steffen Koschmieder, Ciro Roberto Rinaldi, Mark M. Jones, Yasmin Hasan, Abdulraheem Yacoub, Mamta Garg, Srdan Verstovsek, Alessandro M. Vannucchi, Dany Habr, Jennifer Byrne, Roger M. Lyons
Publikováno v:
British journal of haematology 176(1), 76-85 (2017). doi:10.1111/bjh.14382
British Journal of Haematology
British Journal of Haematology
British journal of haematology 176(1), 76-85 (2017). doi:10.1111/bjh.14382
Published by Wiley-Blackwell, Oxford [u.a.]
Published by Wiley-Blackwell, Oxford [u.a.]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e854e8aa13c4eea6236c671d85278079
Publikováno v:
Blood. 132:555-555
Background: Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) is a high-risk subtype occurring in 15-30% of older children and adolescents/young adults (AYAs) with B-ALL. Ph-like ALL is associated with high relapse rates and poo
Autor:
Tiziano Barbui, Xiaolei Zhou, Ruben A. Mesa, Deborah S. Hunter, Jean-Jacques Kiladjian, Richard S. Levy, Giovanni Barosi, Alessandro M. Vannucchi, Margaret Squier, Catherine Copley-Merriman, Francesco Passamonti, Laurent Knoops, Claire N. Harrison, Francisco Cervantes, Haifa Kathrin Al-Ali, Estella Mendelson, Heinz Gisslinger, Andres Sirulnik
Publikováno v:
British Journal of Haematology. 162:229-239
Patients with myelofibrosis (MF) have significant debilitating symptoms, physical disabilities, and poor health-related quality of life (HRQoL). Here, we report post-hoc analyses of the impact of ruxolitinib, a potent and selective JAK1 and JAK2 inhi
Publikováno v:
Annals of the New York Academy of Sciences. 948:100-111
Xenoestrogens with endocrine disrupting activity have been associated with the dysregulation of reproductive function and promotion of malignancies in experimental animals and human populations. The high incidence of uterine leiomyomas, a benign estr
Publikováno v:
Genes, Chromosomes and Cancer. 38:349-356
Eker rats carry a defect in the Tsc-2 tumor suppressor gene and female Eker rats develop uterine leiomyoma with a high frequency. The presentation, response to hormones and molecular alterations in these mesenchymal smooth muscle tumors, closely rese