Zobrazeno 1 - 10 of 25 pro vyhledávání: '"Deborah Rotoli"'
1
Akademický článek
STAT3 silencing by an aptamer-based strategy hampers the crosstalk between NSCLC cells and cancer-associated fibroblasts
Autor: Maria L. Ibba, Giuseppe Ciccone, Deborah Rotoli, Gabriele Coppola, Alfonso Fiorelli, Silvia Catuogno, Carla L. Esposito
Publikováno v: Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 111-126 (2023)
The identification of new effective therapeutic options for non-small-cell lung cancer (NSCLC) represents a crucial challenge in oncology. Recent studies indicate that cancer-associated fibroblasts (CAFs) participate in tumor progression by establish
Externí odkaz: https://doaj.org/article/355f7b2b64c748fa9e32d04320a16a88
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2
Akademický článek
Identification of a novel RNA aptamer that selectively targets breast cancer exosomes
Autor: Carla Lucia Esposito, Cristina Quintavalle, Francesco Ingenito, Deborah Rotoli, Giuseppina Roscigno, Silvia Nuzzo, Renato Thomas, Silvia Catuogno, Vittorio de Franciscis, Gerolama Condorelli
Publikováno v: Molecular Therapy: Nucleic Acids, Vol 23, Iss , Pp 982-994 (2021)
Breast cancer is a leading cause of cancer mortality in women. Despite advances in its management, the identification of new options for early-stage diagnosis and therapy of this tumor still represents a crucial challenge. Increasing evidence indicat
Externí odkaz: https://doaj.org/article/c40392047de44fa0975ab4413f89e90d
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3
Akademický článek
Molecular-Morphological Relationships of the Scaffold Protein FKBP51 and Inflammatory Processes in Knee Osteoarthritis
Autor: Fabián Poletti, Rebeca González-Fernández, María-del-Pino García, Deborah Rotoli, Julio Ávila, Ali Mobasheri, Pablo Martín-Vasallo
Publikováno v: Cells, Vol 10, Iss 9, p 2196 (2021)
Knee osteoarthritis (OA) is one of the most prevalent chronic conditions affecting the adult population. OA is no longer thought to come from a purely biomechanical origin but rather one that has been increasingly recognized to include a persistent l
Externí odkaz: https://doaj.org/article/055b61c2e943406db44a299d9ea5e78a
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4
AmotL2, IQGAP1, and FKBP51 Scaffold Proteins in Glioblastoma Stem Cell Niches
Autor: Pablo Martín-Vasallo, Ricardo Gutiérrez, Deborah Rotoli, Julio Ávila, Manuel Morales, Lucio Díaz-Flores
Publikováno v: J Histochem Cytochem
Glioma stem cells (GSCs) live in a continuous process of stemness reprogramming to achieve specific cell commitment within the so-called GSC niches, specifically located in periarteriolar regions. In this review, we analyze the expression levels, cel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8564bbe13d4d8c78d3a7fb11915b5091
https://pubmed.ncbi.nlm.nih.gov/34165350
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5
Selection of a Nuclease-Resistant RNA Aptamer Targeting CD19
Autor: Carla Lucia Esposito, Vittorio de Franciscis, George A. Calin, Annamaria Sandomenico, William G. Wierda, Deborah Rotoli, Silvia Catuogno, Gianluca Santamaria, Alessandra Ferrajoli, Katrien Van Roosbroeck, Menotti Ruvo
Publikováno v: Cancers
Volume 13
Issue 20
Cancers, Vol 13, Iss 5220, p 5220 (2021)
Simple Summary Haematological malignancies show a constantly growing incidence, accounting for 6.5% of new cancer cases worldwide. Among them, B-cell neoplasms often show resistance to conventional chemotherapy that is also associated with numerous a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbe48694ed4afcaee58942250b82f67
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6
IQGAP1, AmotL2, and FKBP51 Scaffoldins in the Glioblastoma Microenvironment
Autor: María-Del-C Maeso, Cornelis J.F. Van Noorden, Manuel Morales, Deborah Rotoli, Natalia Dolores Pérez-Rodríguez, Ali Mobasheri, Julio Ávila, Pablo Martín-Vasallo
Publikováno v: J Histochem Cytochem
journal of histochemistry and cytochemistry, 67(7), 481-494. Histochemical Society Inc.
Journal of histochemistry and cytochemistry (Online) 67 (2019): 481–494. doi:10.1369/0022155419833334
info:cnr-pdr/source/autori:Rotoli D.; Morales M.; Maeso M.-D.-C.; Avila J.; Perez-Rodriguez N.D.; Mobasheri A.; van Noorden C.J.F.; Martin-Vasallo P./titolo:IQGAP1, AmotL2, and FKBP51 Scaffoldins in the Glioblastoma Microenvironment/doi:10.1369%2F0022155419833334/rivista:Journal of histochemistry and cytochemistry (Online)/anno:2019/pagina_da:481/pagina_a:494/intervallo_pagine:481–494/volume:67
Glioblastoma (GB) is the most frequently occurring and aggressive primary brain tumor. Glioma stem cells (GSCs) and astrocytoma cells are the predominant malignant cells occurring in GB besides a highly heterogeneous population of migrating, neovascu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb05ffff439160db4b158690f94af849
https://doi.org/10.1369/0022155419833334
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7
Celastrol Prevents Oxidative Stress Effects on FSHR, PAPP, and CYP19A1 Gene Expression in Cultured Human Granulosa-Lutein Cells
Autor: Angela Palumbo, Rebeca González-Fernández, Rita Martín-Ramírez, J. Hernandez, Pablo Martín-Vasallo, Deborah Rotoli, Julio Ávila
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 3596, p 3596 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 7
Regulation of oxidative stress (OS) is important to prevent damage to female reproductive physiology. While normal OS levels may have a regulatory role, high OS levels may negatively affect vital processes such as folliculogenesis or embryogenesis. T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ad50f65be27b67e19544fbdfe155e96
https://www.mdpi.com/1422-0067/22/7/3596
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8
Targeting breast cancer exosomes with nucleic aptamers: innovative tools for early diagnosis and therapy
Autor: Carla Lucia Esposito, Silvia Nuzzo, Zoran Minic, Consiglio Nazionale delle Ricerche, Francesco Ingenito, Vittorio de Franciscis, Renato Thomas, Silvia Catuogno, Cristina Quintavalle, Irccs Sdn, Mediterranea Cardiocentro, Deborah Rotoli, Gerolama Condorelli, Giuseppina Roscigno, Maxim V. Berezovski
Publikováno v: Siberian Medical Review.
Exosomes are emerging as promising target for early diagnosis and therapy in diff erent oncological conditions including breast cancer (BC). However, the development of tools able to easily and specifi cally target cancer cell-derived exosomes still
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f6c09f58233eb7732bc635da8656a5a2
https://doi.org/10.20333/25000136-2021-2-104
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9
Identification of a novel RNA aptamer that selectively targets breast cancer exosomes
Autor: Renato Thomas, Cristina Quintavalle, Carla Lucia Esposito, Vittorio de Franciscis, Francesco Ingenito, Silvia Nuzzo, Gerolama Condorelli, Deborah Rotoli, Giuseppina Roscigno, Silvia Catuogno
Publikováno v: Molecular Therapy. Nucleic Acids
Molecular Therapy-Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 23, Iss, Pp 982-994 (2021)
Breast cancer is a leading cause of cancer mortality in women. Despite advances in its management, the identification of new options for early-stage diagnosis and therapy of this tumor still represents a crucial challenge. Increasing evidence indicat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df620de22e10684e629d64aab482abb
http://hdl.handle.net/11588/845719
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10
Advances in Oligonucleotide Aptamers for NSCLC Targeting
Autor: Carla Lucia Esposito, Maria L Ibba, Deborah Rotoli, Silvia Catuogno, Laura Santana-Viera
Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 6075, p 6075 (2020)
International Journal of Molecular Sciences
International journal of molecular sciences (Online) 21 (2020): 1–27. doi:10.3390/ijms21176075
info:cnr-pdr/source/autori:Rotoli D.; Santana-Viera L.; Ibba M.L.; Esposito C.L.; Catuogno S./titolo:Advances in oligonucleotide aptamers for NSCLC targeting/doi:10.3390%2Fijms21176075/rivista:International journal of molecular sciences (Online)/anno:2020/pagina_da:1/pagina_a:27/intervallo_pagine:1–27/volume:21
Non-small-cell lung cancer (NSCLC) is the most common type of lung cancer worldwide, with the highest incidence in developed countries. NSCLC patients often face resistance to currently available therapies, accounting for frequent relapses and poor p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d04a371d8a492d8933601bca2f1609a
https://www.mdpi.com/1422-0067/21/17/6075
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