Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Deborah R. Leon"'
Autor:
Dung N. Nguyen, Bokai Xu, Robyn L. Stanfield, Jennifer K. Bailey, Satoru Horiya, J. Sebastian Temme, Deborah R. Leon, Celia C. LaBranche, David C. Montefiori, Catherine E. Costello, Ian A. Wilson, Isaac J. Krauss
Publikováno v:
ACS Central Science, Vol 5, Iss 2, Pp 237-249 (2019)
Externí odkaz:
https://doaj.org/article/9f4707366b53402dbecdc17a9b42eefa
Autor:
Lars Rohlin, Deborah R. Leon, Unmi Kim, Joseph A. Loo, Rachel R. Ogorzalek Loo, Robert P. Gunsalus
Publikováno v:
Archaea, Vol 2012 (2012)
Many archaeal cell envelopes contain a protein coat or sheath composed of one or more surface exposed proteins. These surface layer (S-layer) proteins contribute structural integrity and protect the lipid membrane from environmental challenges. To ex
Externí odkaz:
https://doaj.org/article/c04b35e8e77444cc908a3b4d222d2d09
Autor:
Nickita Mehta, Kevin B. Chandler, Todd J. Suscovich, Catherine E. Costello, Deborah R. Leon, Galit Alter
Publikováno v:
Molecular & Cellular Proteomics. 18:686-703
Antibodies are critical glycoproteins that bridge the innate and adaptive immune systems to provide protection against infection. The isotype/subclass of the antibody, the co-translational N-glycosylation on the CH2 domain, and the remodeling of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e80065084be1a17e55747f997d9812b
https://doi.org/10.1074/mcp.ra118.001185
https://doi.org/10.1074/mcp.ra118.001185
Autor:
Giulia Bandini, Deborah R. Leon, Catherine E. Costello, John Samuelson, Lara K. Mahal, Carolina Agop-Nersesian, Carolin M Hoppe, Françoise H. Routier, Melanie J. Shears, Yue Zhang
Publikováno v:
Journal of Biological Chemistry. 294:1967-1983
Toxoplasma gondii is an intracellular parasite that causes disseminated infections that can produce neurological damage in fetuses and immunocompromised individuals. Microneme protein 2 (MIC2), a member of the thrombospondin-related anonymous protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f20e41789cb9ae4beb5aabc7744d42f5
https://doi.org/10.1074/jbc.ra118.005179
https://doi.org/10.1074/jbc.ra118.005179
Autor:
Kshitij Khatri, Chun Shao, Nicole K. Polinski, Joseph Zaia, Rekha Raghunathan, Deborah R. Leon, Fredric P. Manfredsson, Mark E. McComb, Joshua A. Klein, John D. Hogan, Caryl E. Sortwell
Publikováno v:
Molecular & Cellular Proteomics. 17:1778-1787
Parkinson's disease (PD) is a neurological disorder characterized by the progressive loss of functional dopaminergic neurons in the nigrostriatal pathway in the brain. Although current treatments provide only symptomatic relief, gene therapy has the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a010b58bc7a572ac17c064deadddce
https://doi.org/10.1074/mcp.ra118.000680
https://doi.org/10.1074/mcp.ra118.000680
Autor:
Hans Bakker, Andreia Albuquerque-Wendt, Catherine E. Costello, Carolin M Hoppe, Luis Izquierdo, Aleksandra Shcherbakova, Giulia Bandini, Françoise H. Routier, Deborah R. Leon, Falk F. R. Buettner
Publikováno v:
Glycobiology. 28:333-343
In many metazoan species, an unusual type of protein glycosylation, called C-mannosylation, occurs on adhesive thrombospondin type 1 repeats (TSRs) and type I cytokine receptors. This modification has been shown to be catalyzed by the Caenorhabditis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec02c590a429d81a921da01c8d14963
https://doi.org/10.1093/glycob/cwy013
https://doi.org/10.1093/glycob/cwy013
Autor:
Deborah R. Leon, Joshua A. Klein, Joseph Zaia, John R. Haserick, Mark E. McComb, Kshitij Khatri, Catherine E. Costello
Publikováno v:
Analytical Chemistry. 89:6645-6655
Glycomics and glycoproteomics analyses by mass spectrometry require efficient front-end separation methods to enable deep characterization of heterogeneous glycoform populations. Chromatography methods are generally limited in their ability to resolv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6631ff78fc17c7def03b22b245c01690
https://doi.org/10.1021/acs.analchem.7b00875
https://doi.org/10.1021/acs.analchem.7b00875
Autor:
Catherine E. Costello, Yu Huang, Jiyang Zhang, Elise E. Drouin, Chunxiang Yao, Allen C. Steere, Deborah R. Leon, Qi Wang
Publikováno v:
Journal of Proteome Research. 16:122-136
HLA-DR-molecules are highly expressed in synovial tissue (ST), the target of the immune response in chronic inflammatory forms of arthritis. Here, we used LC-MS/MS to identify HLA-DR-presented self-peptides in cells taken directly from clinical sampl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eea83aef857c5daf936cb66ce888c209
https://doi.org/10.1021/acs.jproteome.6b00386
https://doi.org/10.1021/acs.jproteome.6b00386
Autor:
Kevin Brown, Chandler, Nickita, Mehta, Deborah R, Leon, Todd J, Suscovich, Galit, Alter, Catherine E, Costello
Publikováno v:
Molecularcellular proteomics : MCP. 18(4)
Antibodies are critical glycoproteins that bridge the innate and adaptive immune systems to provide protection against infection. The isotype/subclass of the antibody, the co-translational N-glycosylation on the CH2 domain, and the remodeling of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::87a022d4adaaa030c3fad3cd34848f89
https://pubmed.ncbi.nlm.nih.gov/30659065
https://pubmed.ncbi.nlm.nih.gov/30659065
Autor:
Alex J, McDonald, Deborah R, Leon, Kathleen A, Markham, Bei, Wu, Christian F, Heckendorf, Kevin, Schilling, Hollis D, Showalter, Philip C, Andrews, Mark E, McComb, M Jake, Pushie, Catherine E, Costello, Glenn L, Millhauser, David A, Harris
Publikováno v:
Structure
The cellular isoform of the prion protein (PrP(C)) serves as precursor to the infectious isoform (PrP(Sc)), and as a cell-surface receptor, which binds misfolded protein oligomers as well as physiological ligands such as Cu(2+) ions. PrP(C) consists
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ec182716fe673fbd7ef9920baf6e3e6a
https://pubmed.ncbi.nlm.nih.gov/30956132
https://pubmed.ncbi.nlm.nih.gov/30956132