Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Deborah Philp"'
Over-expression of thymosin beta4 promotes abnormal tooth development and stimulation of hair growth
Publikováno v:
The International Journal of Developmental Biology. 54:135-140
Thymosin beta 4 has multi-functional roles in cell physiology. It accelerates wound healing, hair growth and angiogenesis, and increases laminin-5 expression in corneal epithelium. Furthermore, thymosin beta 4 stimulates tumor growth and metastasis b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b021cc875a461956d82b8cf4ba517b
https://doi.org/10.1387/ijdb.082735hc
https://doi.org/10.1387/ijdb.082735hc
Publikováno v:
Wound Repair and Regeneration. 13:A28-A48
Impaired wound healing is a problem for immobilized patients, diabetics, and the elderly. The 43 amino acid angiogenic peptide thymosin β4 has previously been found to promote accelerated dermal wound repair in rats, aged mice and db/db diabetic mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f844bacb2aa1733ce0c5ff3f32396aa
https://doi.org/10.1111/j.1067-1927.2005.130216a.x
https://doi.org/10.1111/j.1067-1927.2005.130216a.x
Autor:
Deborah Philp, Hynda K. Kleinman, Mayumi Mochizuki, Yoshihiko Yamada, Kentaro Hozumi, Nobuharu Suzuki, Motoyoshi Nomizu
Publikováno v:
Archives of Biochemistry and Biophysics. 459:249-255
The AG73 peptide (RKRLQVQLSIRT, mouse laminin alpha 1 chain 2719-2730) promotes cell adhesion and tumor metastasis, and interacts with transmembrane syndecan proteoglycans. Here, we demonstrate AG73 peptide angiogenic activity using in vitro, ex vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba854fdef69174655fd5b8a684d1921
https://doi.org/10.1016/j.abb.2006.12.026
https://doi.org/10.1016/j.abb.2006.12.026
Autor:
Kedesha Sibliss, Hynda K. Kleinman, Mychi Nguyen, Deborah Philp, Min Zhou, Larry M. Wahl, Esther L. Fine, Matthew P. Hoffman, Brooke Scheremeta
Publikováno v:
Journal of Cellular Physiology. 208:195-200
Immobilized patients, diabetics, and the elderly suffer from impaired wound healing. The 43-amino acid angiogenic peptide thymosin β4 (Tβ4) has previously been found to accelerate dermal wound repair in rats, aged mice, and db/db diabetic mice. It
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d49319b27ea5f31b08437d340df53777
https://doi.org/10.1002/jcp.20650
https://doi.org/10.1002/jcp.20650
Autor:
Leonid Margolis, Hynda K. Kleinman, Deborah Philp, Wendy Fitzgerald, Silvia Chen, Jan M. Orenstein
Publikováno v:
STEM CELLS. 23:288-296
Most cells in tissues contact an extracellular matrix on at least one surface. These complex mixtures of interacting proteins provide structural support and biological signals that regulate cell differentiation and may be important for stem cell diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00b9110066747a4aefc34fc07cb1f08
https://doi.org/10.1634/stemcells.2002-0109
https://doi.org/10.1634/stemcells.2002-0109
Autor:
Jung-Im Huh, Rakesh K. Kumar, Deborah Philp, Jeffrey Stafford, Alfonso Calvo, Jeffrey E. Green, Hynda K Kleinman, Mui Cheung
Publikováno v:
Oncogene. 24:790-800
Cancer growth and progression is often critically influenced by the production of vascular endothelial growth factor (VEGF), a key mediator of angiogenesis. VEGF produced by tumor cells stimulates endothelial cell growth through the binding and activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2470af9aed4f6c824c234b67620e5151
https://doi.org/10.1038/sj.onc.1208221
https://doi.org/10.1038/sj.onc.1208221
Autor:
Adam Orgel, Hynda K. Kleinman, Ana M. Villa, Brooke Scheremeta, Sharleen St-Surin, Deborah Philp, Mychi Nguyen, Michael Elkin
Publikováno v:
The FASEB Journal. 18:1-16
Thymosin beta4, a 43-amino acid polypeptide that is an important mediator of cell migration and differentiation, also promotes angiogenesis and wound healing. Here, we report that thymosin beta4 stimulates hair growth in normal rats and mice. A speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eba4ab0cb05be634f45396898572c1bf
https://doi.org/10.1096/fj.03-0244fje
https://doi.org/10.1096/fj.03-0244fje
Autor:
Jun Yang, Adebowale Adeyemi, William Boto, Karen D. King, Jerry C. Guyden, Deborah Philp, Mark Pezzano, Birdette Gardiner, Michael Samms
Publikováno v:
Cellular Immunology. 185:123-133
A thymic epithelial cell line (tsTNC-1) that maintains the ability to selectively bind and internalize immature alpha beta TCRloCD4+CD8+ thymocytes in vitro was used in the development of a monoclonal antibody that is specific to the cell surface of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06769b7a630f0e49b752f65b6bad320b
https://doi.org/10.1006/cimm.1998.1279
https://doi.org/10.1006/cimm.1998.1279
Autor:
Robert W. Maitta, Mark Pezzano, Deborah Philp, Sharon Stephenson, Yang Li, Vincent Reid, Jerry C. Guyden
Publikováno v:
Cellular Immunology. 169:174-184
A temperature-sensitive line of thymic nurse cells (tsTNC-1) that maintains the ability to selectively internalize immature alpha beta TCRloCD4+CD8+ thymocytes in vitro was used in long-term coincubation experiments to determine nurse cell function d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7faaa1ca544adef4a3ec0f6401719aec
https://doi.org/10.1006/cimm.1996.0108
https://doi.org/10.1006/cimm.1996.0108
Autor:
Deborah, Philp, Hynda K, Kleinman
Publikováno v:
Annals of the New York Academy of Sciences. 1194
Studies in various animal models of disease and repair with thymosin beta(4) (Tbeta(4)), the major actin-sequestering molecule in mammalian cells, have provided the scientific foundation for the ongoing dermal, corneal, and cardiac wound repair multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0fbdabc30e1184f0b4279109a567acae
https://pubmed.ncbi.nlm.nih.gov/20536453
https://pubmed.ncbi.nlm.nih.gov/20536453